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The map label for this gene is dnaQ [H]

Identifier: 29142975

GI number: 29142975

Start: 2678123

End: 2678854

Strand: Reverse

Name: dnaQ [H]

Synonym: t2601

Alternate gene names: 29142975

Gene position: 2678854-2678123 (Counterclockwise)

Preceding gene: 29142977

Following gene: 29142966

Centisome position: 55.9

GC content: 51.64

Gene sequence:

>732_bases
ATGAGCACTGCAATTACACGACAGATTGTCCTCGATACCGAAACCACCGGTATGAACCAGATAGGCGCGCACTATGAAGG
TCACAAGATTATTGAGATCGGTGCGGTTGAGGTGATAAACCGTCGTCTGACCGGCAACAATTTTCATGTTTACCTGAAGC
CGGATCGGCTGGTGGATCCGGAAGCGTTTGGCGTACACGGTATTGCCGATGAGTTTCTGCTGGATAAGCCGGTTTTTGCT
GATGTGGTCGATGAGTTTCTCGATTATATCCGCGGCGCGGAGCTGGTCATCCATAACGCATCGTTCGATATCGGCTTTAT
GGATTATGAGTTTGGTCTGCTTAAACGCGATATTCCTAAAACCAATACTTTCTGCAAAGTTACCGATAGCCTGGCGTTGG
CGCGGAAAATGTTCCCCGGCAAGCGTAACAGCCTTGATGCGCTGTGTTCGCGTTATGAGATAGATAATAGCAAACGTACT
TTGCACGGCGCATTGCTCGATGCCCAGATCCTTGCCGAAGTGTATCTGGCGATGACGGGCGGACAAACGTCCATGACGTT
TGCGATGGAAGGAGAGACGCAACGGCAGCAAGGTGAAGCGACCATTCAGCGAATCGTTCGCCAGGCCAGCCGGTTACGGG
TCGTTTTTGCCTCTGAGGAAGAGCTGGCTGCGCATGAATCGCGGCTTGATCTGGTGCAGAAAAAGGGCGGAAGTTGCCTT
TGGCGGGCATAA

Upstream 100 bases:

>100_bases
AAGAGCCATCGGTGAAAATTTCTACCTGTTTAAGCATCTCTGGTAGACTTCCTGTAATTGAAATCGATAACAAAACGCAA
GTCTGACATAAATGACCGAT

Downstream 100 bases:

>100_bases
TTTATTCCTTTTTAGGCTATAAAAATCATCCTTCGGGCGATTTTTGCAGCAACTGATTCAAAAGGTGAGAAAAAGCGTTG
ACGGGCGACACCGCAAACCG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVINRRLTGNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPVFA
DVVDEFLDYIRGAELVIHNASFDIGFMDYEFGLLKRDIPKTNTFCKVTDSLALARKMFPGKRNSLDALCSRYEIDNSKRT
LHGALLDAQILAEVYLAMTGGQTSMTFAMEGETQRQQGEATIQRIVRQASRLRVVFASEEELAAHESRLDLVQKKGGSCL
WRA

Sequences:

>Translated_243_residues
MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVINRRLTGNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPVFA
DVVDEFLDYIRGAELVIHNASFDIGFMDYEFGLLKRDIPKTNTFCKVTDSLALARKMFPGKRNSLDALCSRYEIDNSKRT
LHGALLDAQILAEVYLAMTGGQTSMTFAMEGETQRQQGEATIQRIVRQASRLRVVFASEEELAAHESRLDLVQKKGGSCL
WRA
>Mature_242_residues
STAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVINRRLTGNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPVFAD
VVDEFLDYIRGAELVIHNASFDIGFMDYEFGLLKRDIPKTNTFCKVTDSLALARKMFPGKRNSLDALCSRYEIDNSKRTL
HGALLDAQILAEVYLAMTGGQTSMTFAMEGETQRQQGEATIQRIVRQASRLRVVFASEEELAAHESRLDLVQKKGGSCLW
RA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=243, Percent_Identity=93.4156378600823, Blast_Score=483, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 27225; Mature: 27094

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVINRRLTGNNFHVYLKPDRLVDP
CCCCCEEEEEEECCCCCCHHHCCCCCCCEEEEEHHHHHHHHHCCCCCEEEEECCCCCCCC
EAFGVHGIADEFLLDKPVFADVVDEFLDYIRGAELVIHNASFDIGFMDYEFGLLKRDIPK
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHHHHHHHCCCCC
TNTFCKVTDSLALARKMFPGKRNSLDALCSRYEIDNSKRTLHGALLDAQILAEVYLAMTG
CCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GQTSMTFAMEGETQRQQGEATIQRIVRQASRLRVVFASEEELAAHESRLDLVQKKGGSCL
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCCCEE
WRA
CCC
>Mature Secondary Structure 
STAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVINRRLTGNNFHVYLKPDRLVDP
CCCCEEEEEEECCCCCCHHHCCCCCCCEEEEEHHHHHHHHHCCCCCEEEEECCCCCCCC
EAFGVHGIADEFLLDKPVFADVVDEFLDYIRGAELVIHNASFDIGFMDYEFGLLKRDIPK
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHHHHHHHCCCCC
TNTFCKVTDSLALARKMFPGKRNSLDALCSRYEIDNSKRTLHGALLDAQILAEVYLAMTG
CCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GQTSMTFAMEGETQRQQGEATIQRIVRQASRLRVVFASEEELAAHESRLDLVQKKGGSCL
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCCCEE
WRA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]