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The map label for this gene is sinR [H]

Identifier: 29142934

GI number: 29142934

Start: 2631487

End: 2632431

Strand: Reverse

Name: sinR [H]

Synonym: t2554

Alternate gene names: 29142934

Gene position: 2632431-2631487 (Counterclockwise)

Preceding gene: 29142935

Following gene: 29142933

Centisome position: 54.93

GC content: 39.47

Gene sequence:

>945_bases
ATGGAACTGATCAATAATCGTGGTATGCGAGATTGGATGATATTTATTAAAGTGGCGGAAGTAGGGAATCTTTCCCGGGC
TGCGCGGGAATTAGATATTAGCATTTCTGCTGTCAGTAAATCGCTTAGTCGCCTTGAGAATTCTATTGAGGTTACTTTAC
TTCGGCGCGATTCACATCACTTAGAGCTGACTGGAGCTGGTCAGACAGCCTATGCAAGCATGAAAAGGATAACATCTTCC
TTTCAGTCCTTGCTGGATGAATTGCGAAATCCGGATAAAATTATCAGAGGGAGTATAAAATTTTCGGCTCCGGCTATTGT
CTGTGAGTTTCTTGCCAATAAGTGGATATGGGAATTTACAGCTAGCTATCCGGATACAAAAATCTACCTGGATTCACGAG
AGCGTAGCGATTTTTTTAGTAAATCCCTGGAGTTTGATGAGCTGGTTTTTAAAAGTGGCATAATCGAAAGTGAGGATCTC
GTGTATCGAAAGATAAGCCCTTTAAAGTTGGTTCTTTGTGCAAGTCCGAAATATATCAGAAAATATGGCAGGATCTCACA
TCCTGGCGATTTGGAAAATCACATTATTGTGGGTCTTCACAACCATGGTCTTTCCGGACCTCTTACTCTTTTCCGTCAAG
AGGAATCATACACTATTAGTGGCGCTGTTAATGTTCATTTATCTTCCAATAATCTTTTGAGTGTTCTTAATTTGGTTTTA
GAAGGGAAGGGTATCAACCTCATGACTCCGGCCTGGCTTGCCACTAAATACTTAAAAAATAATGAACTTGAAATTATACT
TCCTGAATGGAGAGTTCCAGATCTCCCCATTTATCTTGTATGGCGTCATCGTCAGTATTATTCTCCTTTATTTCAACGCT
TTCTGTCTTTTATTGAAGATAAATGGAATAATCGCCCACAAATTGATTTTCTGAATGATGATTAA

Upstream 100 bases:

>100_bases
TTATGATGATATCAAGGACATTGAGGCACACAATGACGCATCAGTAAGTCGTTGATAGCTCCTTTAATATAAGAATTTCT
TTTATCAACGGAAGATAATG

Downstream 100 bases:

>100_bases
CTCGTTTGGAATGGTTTTGACACGTTCCTGACTTAAACCCACATGATGATGACTGAATTGAGGCATCGAGATATGCGACT
GGCCGGCCAGTCGTCTTTTG

Product: LysR family transcriptional regulator SinR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITSS
FQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESEDL
VYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQEESYTISGAVNVHLSSNNLLSVLNLVL
EGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD

Sequences:

>Translated_314_residues
MELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITSS
FQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESEDL
VYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQEESYTISGAVNVHLSSNNLLSVLNLVL
EGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD
>Mature_314_residues
MELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITSS
FQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESEDL
VYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQEESYTISGAVNVHLSSNNLLSVLNLVL
EGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD

Specific function: Probable regulatory protein. Its target is not known [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=308, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789639, Length=274, Percent_Identity=23.3576642335766, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789440, Length=302, Percent_Identity=26.8211920529801, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=24.496644295302, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI87081978, Length=268, Percent_Identity=25.3731343283582, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36207; Mature: 36207

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHH
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCE
LELTGAGQTAYASMKRITSSFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFT
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHCCEEEEEE
ASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESEDLVYRKISPLKLVLCASPKYIR
CCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCHHEEECCCEEEEEECCCHHHH
KYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQEESYTISGAVNVHLSSNNLLSVLNLVL
HHCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEEEEEEECCCCHHHHHHHHH
EGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIED
CCCCCCEECHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
KWNNRPQIDFLNDD
HCCCCCCEEECCCC
>Mature Secondary Structure
MELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHH
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCE
LELTGAGQTAYASMKRITSSFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFT
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHCCEEEEEE
ASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESEDLVYRKISPLKLVLCASPKYIR
CCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCHHEEECCCEEEEEECCCHHHH
KYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQEESYTISGAVNVHLSSNNLLSVLNLVL
HHCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEEEEEEECCCCHHHHHHHHH
EGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIED
CCCCCCEECHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
KWNNRPQIDFLNDD
HCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8430070; 11677609 [H]