Click here to switch to the map view.

The map label for this gene is rtn [H]

Identifier: 29142902

GI number: 29142902

Start: 2592554

End: 2594128

Strand: Reverse

Name: rtn [H]

Synonym: t2518

Alternate gene names: 29142902

Gene position: 2594128-2592554 (Counterclockwise)

Preceding gene: 29142903

Following gene: 29142901

Centisome position: 54.13

GC content: 48.25

Gene sequence:

>1575_bases
TTGAAAGTAAGAAAGCTATTTCTGATGTTGTTTATTGCCGTTCCACTGATCGTAATGATATTGGTGGGGTTACTCGCGGG
TATCTTCCAGCTAAAACGAGATATCGCCGTCAGCGCCAATACGCTGCTGCGGTTTAGCGCGGATATATCCGCCGCCTCCT
GGCAAGTCGCCGGAAAAGCCGCCAGACTGGCTGAGAGTTCCTGTACTGACACGCTGAAAGAACTGTCCAGAACGCGGGCC
TTCACTCCTTATGTCCGTGACATTGGGTTTCTGGAAAATGGTGATATCACTTGCTCCTTTGTCACAGGAACCGAACGCTA
TCATTTTTCCCGGCTGGCAGGGCTTTCTTTACCTGCTTCTTATCCGGAACGGTGGTTGCGATCTATCGGTAGTATGGCCG
AAGGACCCGATCGCCTTGTTGTGGTGTATGTGAAAAAAGTAGCAGCGGATAAAGCGGCTTTCGTCATTGTGGATTCGCAG
TATGTCCAGGAGCTCATGGAGATATTGGCTGCAGAAAGAGCATCAGCCTTTAGCCTGATATTCGGCGCAGGAGAGGCGAT
TACCAGCGCTGCGACGTTGCGCGGTAAGGCGTTTTTAACGCAGCGGTTCACCTCAACCGATCACACTATCCAGCTGATGG
TGCGAACCCCTTTCTCAACGTTATCGGCATACTGGTTACAAAACCTTTTTATTTTTATTCCGCTGTCATTATGTCTTTCT
GTAGGGATGATATTGTTCTACAGGCGCTGGTATTTAAAACGCTTATCTCTGGCCCGGGAGATTTCCAGGGGAATAACGCA
CAATGAATTTACGGTACATTATCAACCTGTTTTTAATGTTAAACACGGTAGTTGCGGCGGCGTGGAGGCGCTAATGCGCT
GGCCGCAACCGGATGGCCGTTTTATAACTCCCGATATTTTTATTACCGCCGCAGAAAATGAAGGCATGATTATTCCACTC
TCTCGTCATCTGTTCGAACTGATTGCTCATGACGTGATAAACTGGACTGTACCGGATGATTTCTATATCAGCGTAAATAT
ATCGCCTGCGCATCTTATGGATGACGGTTTTATACAAGATATAGAGGCGCTCAGGACTCGTTTGGGAACGATAACGCTTA
TGTTGGAGCTCACCGAACGTAGCCTGATTGTAGAACCTTCACAGGTCGCAGAAAAACTTTCAACGCTCCGTGAAAAAGGC
GTGTTAATAGCGATTGATGATTTTGGGACCGGCTATTGCTCCCTCTCCTATCTCCAGCAATTACCTGTAGACTCTCTTAA
AATAGACAGAACGTTTATCGATACCATTGATACCAGCAGCGATGATGTTCCTGTCCTGGATACTATCATTACGCTGAGTC
AGCGACTGGGACTCAATGTGGTTGCCGAAGGGGTCAGTACCCAGCACCAATTGCGTTACATCTTAAGCCACGGGGTAGGA
TTCGTTCAGGGATTTCTTTATGCCAGGCCGATGGGGACTAATGACTTTATGAGTTGGCTTGGCAAGTCAGCCCAGCGGCA
AAATGGTTTGCTCAAGGGGGAAAGCGGATCCGCGAGCGATCTGGTGGCTGAATAA

Upstream 100 bases:

>100_bases
ATAACCTATCTCTCAATATTTCTTTTCTCTATTAATGTTACTTTAGTTATCCTATAAAAGCGTACAGTGGCAAAAGGAAG
GCCGGTAAGAGGGCAATGAT

Downstream 100 bases:

>100_bases
TGCAGGAACTCGCTACGGAAAAAAATTCAATAGCACGATATATCCTAGTAATATGTTTATGCCGTGAAGAAACGTGATAG
CACTGGGGCGGATATTTTTA

Product: rtn protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKAARLAESSCTDTLKELSRTRA
FTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPASYPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQ
YVQELMEILAAERASAFSLIFGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
VGMILFYRRWYLKRLSLAREISRGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPL
SRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKG
VLIAIDDFGTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE

Sequences:

>Translated_524_residues
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKAARLAESSCTDTLKELSRTRA
FTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPASYPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQ
YVQELMEILAAERASAFSLIFGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
VGMILFYRRWYLKRLSLAREISRGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPL
SRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKG
VLIAIDDFGTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE
>Mature_524_residues
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKAARLAESSCTDTLKELSRTRA
FTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPASYPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQ
YVQELMEILAAERASAFSLIFGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
VGMILFYRRWYLKRLSLAREISRGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPL
SRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKG
VLIAIDDFGTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=518, Percent_Identity=30.3088803088803, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI87081845, Length=478, Percent_Identity=28.6610878661088, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87081980, Length=466, Percent_Identity=30.2575107296137, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI87081743, Length=539, Percent_Identity=28.2003710575139, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786507, Length=250, Percent_Identity=37.2, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1790496, Length=328, Percent_Identity=30.1829268292683, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI226510982, Length=250, Percent_Identity=34.8, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787541, Length=255, Percent_Identity=30.1960784313725, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081921, Length=252, Percent_Identity=29.7619047619048, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1787055, Length=249, Percent_Identity=29.718875502008, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788849, Length=254, Percent_Identity=27.9527559055118, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082096, Length=250, Percent_Identity=29.2, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787410, Length=155, Percent_Identity=28.3870967741935, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58262; Mature: 58262

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00136 SUBTILASE_ASP ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEECCCCCCHHHHHHHH
ARLAESSCTDTLKELSRTRAFTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPAS
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEECCCEEEEEEECCCHHHHHHHHCCCCCCC
YPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQYVQELMEILAAERASAFSLI
HHHHHHHHHCCCCCCCCCEEEEEEEHHCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEE
FGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
EECCHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
VGMILFYRRWYLKRLSLAREISRGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCHHHHHHCCCCCCC
FITPDIFITAAENEGMIIPLSRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQD
EECCEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCHHHHH
IEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDFGTGYCSLSYLQQ
HHHHHHHHHHEEEEEEECCCCEEECHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
LPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
CCCCCEEECHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCHH
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE
HHHHHHHCCCCCCHHHHHHHCCHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEECCCCCCHHHHHHHH
ARLAESSCTDTLKELSRTRAFTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPAS
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEECCCEEEEEEECCCHHHHHHHHCCCCCCC
YPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQYVQELMEILAAERASAFSLI
HHHHHHHHHCCCCCCCCCEEEEEEEHHCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEE
FGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
EECCHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
VGMILFYRRWYLKRLSLAREISRGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCHHHHHHCCCCCCC
FITPDIFITAAENEGMIIPLSRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQD
EECCEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCHHHHH
IEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDFGTGYCSLSYLQQ
HHHHHHHHHHEEEEEEECCCCEEECHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
LPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
CCCCCEEECHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCHH
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE
HHHHHHHCCCCCCHHHHHHHCCHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]