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The map label for this gene is gsk [H]

Identifier: 29142758

GI number: 29142758

Start: 2437774

End: 2439078

Strand: Reverse

Name: gsk [H]

Synonym: t2369

Alternate gene names: 29142758

Gene position: 2439078-2437774 (Counterclockwise)

Preceding gene: 29142760

Following gene: 29142751

Centisome position: 50.9

GC content: 53.41

Gene sequence:

>1305_bases
ATGAAATTTCCCGGTAAACGTAAATCCAAACACTATTTTCCCGTCAATGCGCGTGACCCGTTGTTGCAACAAATTCAGCC
AGAACAGGAAACCAACGCCTCCTGGGTCGTCGGTATCGACCAGACGTTGGTGGATATTGAGGCGAAAGTGGATGACGATT
TTATTACACGCTATGGATTAAGCGCCGGGCATTCTCTGGTGATAGAAGACGAGTTGGCGGAGAAGCTGTATCAGGAACTG
ACGCGGGAAAATCTGATCACCCATCAGTTTGCTGGCGGCACCATAGGCAATACGATGCATAATTACTCGGTACTGGCGGA
TGACCGTTCGGTGTTACTGGGCGTGATGTGCAGCAACATTGAGATTGGCAGCTACGCTTATCGCTACCTGTGTAATACTT
CCAGCCGTACCGACCTGAATTATCTGCAAGCGGTAGATGGTCCGATTGGCCGCTGTTTCACGCTGATTGGCGAATCCGGC
GAGCGTACCTTCGCTATCAGCCCCGGCCATATGAATCAGCTACGGGCGGAAAGTATTCCGGAAGCGGTGATCGCTGGCGC
TTCCGCGCTGGTGTTGACCTCATATCTGGTGCGCTGTAAGCCTGGCGAACCGATGCCTGACGCGACGATGAAAGCGATCG
AATACGCGAAAAAGCATAACGTGCCGGTTGTCATGACGCTGGGCACCAAATTTGTGATCGCCGATAATCCGCAGTGGTGG
CAGGCGTTTCTCAAAGAGAATGTCTCGATTCTGGCAATGAATGAAGAAGAAGCGGAAGCGCTGACCGGCGAAAACGACCC
GCTGCTGGCGGCGGATAAGGCGCTGGACTGGGTCGACCTGGTGTTATGCACCGCCGGGCCGATAGGGTTATATATGGCAG
GCTTCACCGAAGAGGAAGCAAAACGTAAAACCCAGCATCCTCTGCTGCCGGGGGCTATTGCTGAATTTAACCAGTATGAA
TTTAGCCGGGCAATGCGCCATAAAGATTGTACTAATCCGCTGCGCGTTTATTCGCATATTGCGCCGTATATGGGCGGGCC
GGAAAAAATCATGAACACCAACGGCGCGGGCGATGGCGCGCTGGCGGCGCTGCTGCACGATATTACGGCGAACAGTTACC
ATCGTAGCAACGTACCGAACTCCAGTAAGCACAAATTCACCTGGCTGACCTATTCGTCGCTGGCGCAGGTGTGTAAATAT
GCTAACCGTGTCAGTTATCAGGTACTGAACCAGCATTCTCCGCGTCTGACACGCGGGCTGCCGGAACGTGAGGACAGCCT
GGAAGAGTCGTACTGGGATCGCTAA

Upstream 100 bases:

>100_bases
GCGATCTCGTCGTCCGATATTGAAACGCCATCGTCCGTCGCGCGCAGCAGGGGGAATGTGCTACCATGCAGCGCTCCGTT
ATTCATCCGTAAGCACAATC

Downstream 100 bases:

>100_bases
TCTGGCTTGCCCGATGGCGCTGCGCGCATCGGGCCGTCCGGCAAACCCTTAACTGGCGACGACTTCACCCGCGGGCGGCG
TTTCAAGCAGTTCCAGCATC

Product: inosine-guanosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFPGKRKSKHYFPVNARDPLLQQIQPEQETNASWVVGIDQTLVDIEAKVDDDFITRYGLSAGHSLVIEDELAEKLYQEL
TRENLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQAVDGPIGRCFTLIGESG
ERTFAISPGHMNQLRAESIPEAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHNVPVVMTLGTKFVIADNPQWW
QAFLKENVSILAMNEEEAEALTGENDPLLAADKALDWVDLVLCTAGPIGLYMAGFTEEEAKRKTQHPLLPGAIAEFNQYE
FSRAMRHKDCTNPLRVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR

Sequences:

>Translated_434_residues
MKFPGKRKSKHYFPVNARDPLLQQIQPEQETNASWVVGIDQTLVDIEAKVDDDFITRYGLSAGHSLVIEDELAEKLYQEL
TRENLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQAVDGPIGRCFTLIGESG
ERTFAISPGHMNQLRAESIPEAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHNVPVVMTLGTKFVIADNPQWW
QAFLKENVSILAMNEEEAEALTGENDPLLAADKALDWVDLVLCTAGPIGLYMAGFTEEEAKRKTQHPLLPGAIAEFNQYE
FSRAMRHKDCTNPLRVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR
>Mature_434_residues
MKFPGKRKSKHYFPVNARDPLLQQIQPEQETNASWVVGIDQTLVDIEAKVDDDFITRYGLSAGHSLVIEDELAEKLYQEL
TRENLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQAVDGPIGRCFTLIGESG
ERTFAISPGHMNQLRAESIPEAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHNVPVVMTLGTKFVIADNPQWW
QAFLKENVSILAMNEEEAEALTGENDPLLAADKALDWVDLVLCTAGPIGLYMAGFTEEEAKRKTQHPLLPGAIAEFNQYE
FSRAMRHKDCTNPLRVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=434, Percent_Identity=94.0092165898618, Blast_Score=865, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 48397; Mature: 48397

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGKRKSKHYFPVNARDPLLQQIQPEQETNASWVVGIDQTLVDIEAKVDDDFITRYGL
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEECCCEEEEEEHHCCHHHHHHHCC
SAGHSLVIEDELAEKLYQELTRENLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNI
CCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCEEEECCHHHHHHHHHCCE
EIGSYAYRYLCNTSSRTDLNYLQAVDGPIGRCFTLIGESGERTFAISPGHMNQLRAESIP
EECCHHHHHEECCCCCCCHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCC
EAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHNVPVVMTLGTKFVIADNPQWW
HHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECEEEEEECCHHHH
QAFLKENVSILAMNEEEAEALTGENDPLLAADKALDWVDLVLCTAGPIGLYMAGFTEEEA
HHHHHCCCEEEEECCHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCHHHEEECCCHHHH
KRKTQHPLLPGAIAEFNQYEFSRAMRHKDCTNPLRVYSHIAPYMGGPEKIMNTNGAGDGA
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCCCCCHHH
LAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKYANRVSYQVLNQHSPRLTRGL
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PEREDSLEESYWDR
CCHHHHHHHHHCCC
>Mature Secondary Structure
MKFPGKRKSKHYFPVNARDPLLQQIQPEQETNASWVVGIDQTLVDIEAKVDDDFITRYGL
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEECCCEEEEEEHHCCHHHHHHHCC
SAGHSLVIEDELAEKLYQELTRENLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNI
CCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCEEEECCHHHHHHHHHCCE
EIGSYAYRYLCNTSSRTDLNYLQAVDGPIGRCFTLIGESGERTFAISPGHMNQLRAESIP
EECCHHHHHEECCCCCCCHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCC
EAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHNVPVVMTLGTKFVIADNPQWW
HHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECEEEEEECCHHHH
QAFLKENVSILAMNEEEAEALTGENDPLLAADKALDWVDLVLCTAGPIGLYMAGFTEEEA
HHHHHCCCEEEEECCHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCHHHEEECCCHHHH
KRKTQHPLLPGAIAEFNQYEFSRAMRHKDCTNPLRVYSHIAPYMGGPEKIMNTNGAGDGA
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCCCCCHHH
LAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKYANRVSYQVLNQHSPRLTRGL
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PEREDSLEESYWDR
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]