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The map label for this gene is fimH [H]

Identifier: 29142708

GI number: 29142708

Start: 2379461

End: 2380468

Strand: Reverse

Name: fimH [H]

Synonym: t2316

Alternate gene names: 29142708

Gene position: 2380468-2379461 (Counterclockwise)

Preceding gene: 29142709

Following gene: 29142707

Centisome position: 49.68

GC content: 51.69

Gene sequence:

>1008_bases
ATGAAAATATACTCAGCGCTATTGCTGGCGGGGACCGCACTCTTTTTCACCCATCCCGCGCTGGCGACGGTTTGCCGTAA
TTCAAACGGGACGGCGACCGATATCTTTTATGACCTGTCAGATGTTTTCACCAGCGGCAATAATCAGCCGGGACAGGTGG
TGACGCTGCTGAAAAAATCAGATTGGTGCGGCGTAAACGCGACGTGCCCGGCGGGGACAACGGTGAATTATACCTACCGA
AGCTATGTATCAGAATTACCGGTACAAAGCACCGAAGGAAATTTTAAATACCTCAAGTTGAATGACTACCTTCTGGGCGC
GATGAGCATAACCGATAGTGTCGCTGGCGTATTTTATCCGCCCCGTAACTATATTCGCATGGGCGTCGACTCTAACGTGT
CGCAGCAAAAGCCGTTTGGCGTGCAGGACTCAAAGCTGGTTTTTAAATTAAAAGTGATACGGCCTTTTATTAATATAGTG
ACGATCCCCCGCCAGACAATGTTTACCGTCTATGTGACGACCTCTACCGGCGACGCGTTGAGCACGCCGGTGTATACCAT
TAGCTACAGCGGCAAAGTGGAAGTACCGCAAAACTGTGAAGTGAATGCCGGACAGGTCGTGGAGTTTGATTTCGGCGATA
TCGGCGCGCCGTTATTTAGTCAGGCGGGAGCGGGTAATCGTCCGCAAGGCGTCACGCCGCAAGCGAAAACTATCGCTATC
AAATGTACCAACGTCGCGGCGCAAGCCTATTTATCGATGCGGCTTGAAGCCGAAAAGGCCTCAGGGCAGGCGATGGTGTC
CGATAACCCGGATTTAGGCTTTGTGGTTGCTAATAGCAACGGTACGCCGCTCACACCCAATAATTTGTCGAGTAAAATTC
CGTTTCATCTTGATGATAACGCCGCCGCTCGCGTAGGTATTCGCGCCTGGCCGATCAGCGTGACGGGGAATAAACCGGCG
GAAGGGCCGTTTACTGCGCGCGGCTATCTACGAGTCGATTATGATTAA

Upstream 100 bases:

>100_bases
GTATCGCCCCTTACGCCCTGGCGGAGGATAGCCTGAAGCAGGCGATTACGATAGCCAGCGCGACCTGTATCCGTCCGTCG
TCATAAAAGGAAAAATAGAG

Downstream 100 bases:

>100_bases
GGAGGCATAATGATTCTTCGGCGCGTTTTCATCGCTATCGGTTGTGTTTTGTTAAGCCCGCTGAGTCAGGCCAACTCATC
TCTGGGCGAAGTGAATATTG

Product: FimH protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLLKKSDWCGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYPPRNYIRMGVDSNVSQQKPFGVQDSKLVFKLKVIRPFINIV
TIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGAPLFSQAGAGNRPQGVTPQAKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGNKPA
EGPFTARGYLRVDYD

Sequences:

>Translated_335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLLKKSDWCGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYPPRNYIRMGVDSNVSQQKPFGVQDSKLVFKLKVIRPFINIV
TIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGAPLFSQAGAGNRPQGVTPQAKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGNKPA
EGPFTARGYLRVDYD
>Mature_335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLLKKSDWCGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYPPRNYIRMGVDSNVSQQKPFGVQDSKLVFKLKVIRPFINIV
TIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGAPLFSQAGAGNRPQGVTPQAKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGNKPA
EGPFTARGYLRVDYD

Specific function: Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Seems to be a mannose-binding adhesin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI145693100, Length=326, Percent_Identity=68.0981595092024, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI1787173, Length=254, Percent_Identity=25.9842519685039, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789534, Length=317, Percent_Identity=27.7602523659306, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36109; Mature: 36109

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLLKKS
CCHHHHHHHHHHHHHHHCHHHHHHEECCCCCEEEEEEEHHHHHHCCCCCCCEEEEEEECC
DWCGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYP
CCCCCCCCCCCCCEEEEEHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECCCCCCEEEEC
PRNYIRMGVDSNVSQQKPFGVQDSKLVFKLKVIRPFINIVTIPRQTMFTVYVTTSTGDAL
CHHHEEECCCCCCCCCCCCCCCCCEEEEEEEEHHHCEEEEECCCCEEEEEEEEECCCCCC
STPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGAPLFSQAGAGNRPQGVTPQAKTIAI
CCCEEEEEECCEEECCCCCCCCCCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCCEEEEE
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDN
EEECHHHEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCC
AAARVGIRAWPISVTGNKPAEGPFTARGYLRVDYD
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLLKKS
CCHHHHHHHHHHHHHHHCHHHHHHEECCCCCEEEEEEEHHHHHHCCCCCCCEEEEEEECC
DWCGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVAGVFYP
CCCCCCCCCCCCCEEEEEHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECCCCCCEEEEC
PRNYIRMGVDSNVSQQKPFGVQDSKLVFKLKVIRPFINIVTIPRQTMFTVYVTTSTGDAL
CHHHEEECCCCCCCCCCCCCCCCCEEEEEEEEHHHCEEEEECCCCEEEEEEEEECCCCCC
STPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGAPLFSQAGAGNRPQGVTPQAKTIAI
CCCEEEEEECCEEECCCCCCCCCCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCCEEEEE
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDN
EEECHHHEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCC
AAARVGIRAWPISVTGNKPAEGPFTARGYLRVDYD
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]