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The map label for this gene is entD

Identifier: 29142683

GI number: 29142683

Start: 2355471

End: 2356175

Strand: Direct

Name: entD

Synonym: t2284

Alternate gene names: 29142683

Gene position: 2355471-2356175 (Clockwise)

Preceding gene: 29142682

Following gene: 29142684

Centisome position: 49.15

GC content: 56.17

Gene sequence:

>705_bases
ATGCTGACATCTCATTTTCCCCTTCCCTTTGCCGGACACAGGCTGCATATCGTCGACTTTGATGCGAGCAGCTTTCACGA
ACACGACCTGCTATGGCTGCCTCATCACGATCGGCTCCGGTCTGCCGGACGCAAGCGTAAAGCTGAACATCTGGCAGGCC
GCATCGCTGCCGTTCATGCGCTACGCGAGGTGGGCGTCAGGGCGGTGCCCGGTATTGGCGACAAGCGACAGCCGCTATGG
CCGGACGGCCTATTTGGCAGCATCAGCCACTGTGCGTCAACGGCGCTGGCCGTCATATCCCGACAGCGTGTCGGCGTTGA
TATAGAAAAAATCATGAGTCAGCACACGGCGACAGAGCTGGCGCCGTCCATTATTGATAGCGATGAGCGCCAAATTCTCC
AGGCGAGCTCGCTCCCTTTTCCGCTTGCCCTGACGCTGGCTTTCTCCGCCAAAGAGAGCGTTTATAAAGCCTTTTCAGAC
CGCGTCACGCTCCCGGGATTCGATAGCGCAAAAATTACCTCGCTTAACGCCACGCACATCTCGTTACATCTGCTGCCAGC
CTTTGCCGCCATGATGGCTGAACGTACCGTCCGTACAGAATGGTTTCAACGTGGCAATAGCGTTATTACTCTAGTTTCTG
CAATAACGCGCTTTCCCCACGACAGGAGCGCTCCCGCTTCTATACTTAGCGCAATACCCCGATAA

Upstream 100 bases:

>100_bases
ACCTATAACGAACCGGGACGTACGTGGTATATGAGCATTAATACCCATTTCTGATGGCAACCTTCCCTCCCTCATTCGGG
GAGGGAATTAGCAAAAGACG

Downstream 100 bases:

>100_bases
ATGAGATCGCTATGGCGCTGAATGATTTTCACGTTTCTGAACCTTATACGCTCGGTATTGAGCTGGAGATGCAGGTGATC
AATCCACCTAGCTACGATTT

Product: enterobactin synthase multienzyme complex phosphopantetheinyltransferase

Products: NA

Alternate protein names: Enterobactin synthase component D; Enterochelin synthase D

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRAVPGIGDKRQPLW
PDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATELAPSIIDSDERQILQASSLPFPLALTLAFSAKESVYKAFSD
RVTLPGFDSAKITSLNATHISLHLLPAFAAMMAERTVRTEWFQRGNSVITLVSAITRFPHDRSAPASILSAIPR

Sequences:

>Translated_234_residues
MLTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRAVPGIGDKRQPLW
PDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATELAPSIIDSDERQILQASSLPFPLALTLAFSAKESVYKAFSD
RVTLPGFDSAKITSLNATHISLHLLPAFAAMMAERTVRTEWFQRGNSVITLVSAITRFPHDRSAPASILSAIPR
>Mature_234_residues
MLTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRAVPGIGDKRQPLW
PDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATELAPSIIDSDERQILQASSLPFPLALTLAFSAKESVYKAFSD
RVTLPGFDSAKITSLNATHISLHLLPAFAAMMAERTVRTEWFQRGNSVITLVSAITRFPHDRSAPASILSAIPR

Specific function: Catalyzes the transfer of the 4'-phosphopantetheine moiety from coenzyme A to apo-domains of both entB (an ArCP domain) and entF (a PCP domain). Plays an essential role in the assembly of the enterobactin

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. EntD family

Homologues:

Organism=Escherichia coli, GI1786797, Length=183, Percent_Identity=57.9234972677596, Blast_Score=210, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ENTD_SALTI (Q8Z8L9)

Other databases:

- EMBL:   AL627267
- EMBL:   AE014613
- RefSeq:   NP_455161.1
- RefSeq:   NP_806025.1
- ProteinModelPortal:   Q8Z8L9
- GeneID:   1069366
- GeneID:   1247092
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2284
- KEGG:   sty:STY0627
- HOGENOM:   HBG739719
- OMA:   MKTTHTA
- ProtClustDB:   PRK10251
- BioCyc:   SENT209261:T2284-MONOMER
- BioCyc:   SENT220341:STY0627-MONOMER
- InterPro:   IPR008278
- InterPro:   IPR003542
- PRINTS:   PR01399

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: 2.7.8.-

Molecular weight: Translated: 25739; Mature: 25739

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREVGVRAVPGIGDKRQPLWPDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATEL
HHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
APSIIDSDERQILQASSLPFPLALTLAFSAKESVYKAFSDRVTLPGFDSAKITSLNATHI
HHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHH
SLHLLPAFAAMMAERTVRTEWFQRGNSVITLVSAITRFPHDRSAPASILSAIPR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MLTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREVGVRAVPGIGDKRQPLWPDGLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATEL
HHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
APSIIDSDERQILQASSLPFPLALTLAFSAKESVYKAFSDRVTLPGFDSAKITSLNATHI
HHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHH
SLHLLPAFAAMMAERTVRTEWFQRGNSVITLVSAITRFPHDRSAPASILSAIPR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504