Click here to switch to the map view.

The map label for this gene is ybdR [H]

Identifier: 29142652

GI number: 29142652

Start: 2317011

End: 2318249

Strand: Reverse

Name: ybdR [H]

Synonym: t2252

Alternate gene names: 29142652

Gene position: 2318249-2317011 (Counterclockwise)

Preceding gene: 29142654

Following gene: 29142642

Centisome position: 48.38

GC content: 54.24

Gene sequence:

>1239_bases
ATGAAAGCATTGACGTATCACGGTCCACATCACGTAAAGGTTGAAAACGTACCCGATCCCGGCATTGAGCAGCCTGACGA
TATCATTTTGCGTGTTACCGCCACCGCGATTTGCGGATCTGATTTGCATCTCTATCGCGGCAAGATCCCACAGGTAAAAC
ATGGTGATATTTTCGGCCATGAATTTATGGGCGAGGTGGTGGAAACCGGACATGATGTGAAGAATATTCGGAAAGGGGAT
CGGGTTGTTATCCCGTTCGTCATTGCTTGTGGCGACTGCTTTTTCTGTCGACTACAGCAATATTCAGCGTGTGAAAACAC
TAACGACGGACACGGCGCGGCGATGAATAAAAAACAGATCCCGCCGCCGGCGGCGCTGTTTGGTTATAGCCATCTGTATG
GCGGCGTTCCCGGCGGACAGGCCGAATATGTTCGCGTGCCAAAAGGTAATGTCGGTCCATTTAAGGTGCCGCCGCTGTTA
TCTGACGATAAAGCGCTGTTTCTTTCTGATATTTTGCCTACCGCCTGGCAGGCGGCAAAAAATGCCCAGATTCAGCAACG
TTCCAGCGTGGCGGTTTTTGGCGCAGGGCCGGTAGGATTACTGACTATCGCCTGTGCGCGACTGCTGGGCGCGGAGCAGA
TCTTCGTCGTTGATCACCACGCCTGGCGCCTGCGTTTCGCCGAAGAACGTTACGGCGCGATACCGATCAACTTCGATGAT
GAGAACGATCCGGCGGAAAAAATCATCGAGCAGACGGCAGGACACCGCGGCGTGGACGCGGTAATTGATGCCGTAGGCTT
TGAAGCGAAAGGCAGCATGACGGAGACGGTGCTGACGAACCTTAAACTGGAAGGCAGCAGCGGCAAAGCGCTGCGACAAT
GTATCGCGGCGGTAGGACGCGGCGGCGTGGTCAGCGTGCCCGGCGTGTATGCCGGTTTTATTCACGGCTTTTTATTCGGC
GACGCCTTTGATAAGGGGCTAACTTTTAAAATGGGTCAAACCCATGTTCACGCGTGGCTGGGGGAATTATTACCGCTTAT
TGAAAAAGGGTTGCTGAAGCCGGAGGAGATTGTCACGCACTATATGCCGTTTGAAGAGGCGGCGCGCGGCTACGAAATTT
TCGAAAAACGCGAAGAAGAGTGCCGGAAGGTTATCCTGGTGCCGGGAGCGATGTCGGCACAAGCGGCGCAGAAACAGGCG
ACGGGAGTAATCAACCCGATGCCAGGCGGCGTTGTCTGA

Upstream 100 bases:

>100_bases
CCAGGAAAAATCCTAAAGCCGCCTGTTTTTCCGGTAGTCTCTCCGGGATAGCTACCCTTTTATAGTCGAACGCAACATTC
ACCGTTACCCCGGAGGCTGC

Downstream 100 bases:

>100_bases
AGCAGGCAGAAATGAAAGAGCTAACGGAAAGAGGATGCGCAGGCATCCTCTGTGTAAACGCATTAACGCTTATGCAGATG
GTTTAACGCAGGAAGTCGCC

Product: zinc-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKALTYHGPHHVKVENVPDPGIEQPDDIILRVTATAICGSDLHLYRGKIPQVKHGDIFGHEFMGEVVETGHDVKNIRKGD
RVVIPFVIACGDCFFCRLQQYSACENTNDGHGAAMNKKQIPPPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
SDDKALFLSDILPTAWQAAKNAQIQQRSSVAVFGAGPVGLLTIACARLLGAEQIFVVDHHAWRLRFAEERYGAIPINFDD
ENDPAEKIIEQTAGHRGVDAVIDAVGFEAKGSMTETVLTNLKLEGSSGKALRQCIAAVGRGGVVSVPGVYAGFIHGFLFG
DAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAMSAQAAQKQA
TGVINPMPGGVV

Sequences:

>Translated_412_residues
MKALTYHGPHHVKVENVPDPGIEQPDDIILRVTATAICGSDLHLYRGKIPQVKHGDIFGHEFMGEVVETGHDVKNIRKGD
RVVIPFVIACGDCFFCRLQQYSACENTNDGHGAAMNKKQIPPPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
SDDKALFLSDILPTAWQAAKNAQIQQRSSVAVFGAGPVGLLTIACARLLGAEQIFVVDHHAWRLRFAEERYGAIPINFDD
ENDPAEKIIEQTAGHRGVDAVIDAVGFEAKGSMTETVLTNLKLEGSSGKALRQCIAAVGRGGVVSVPGVYAGFIHGFLFG
DAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAMSAQAAQKQA
TGVINPMPGGVV
>Mature_412_residues
MKALTYHGPHHVKVENVPDPGIEQPDDIILRVTATAICGSDLHLYRGKIPQVKHGDIFGHEFMGEVVETGHDVKNIRKGD
RVVIPFVIACGDCFFCRLQQYSACENTNDGHGAAMNKKQIPPPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
SDDKALFLSDILPTAWQAAKNAQIQQRSSVAVFGAGPVGLLTIACARLLGAEQIFVVDHHAWRLRFAEERYGAIPINFDD
ENDPAEKIIEQTAGHRGVDAVIDAVGFEAKGSMTETVLTNLKLEGSSGKALRQCIAAVGRGGVVSVPGVYAGFIHGFLFG
DAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAMSAQAAQKQA
TGVINPMPGGVV

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=384, Percent_Identity=25.2604166666667, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI71565154, Length=353, Percent_Identity=26.3456090651558, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI156523966, Length=373, Percent_Identity=23.5924932975871, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4501939, Length=245, Percent_Identity=25.7142857142857, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI71565152, Length=362, Percent_Identity=24.585635359116, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4501933, Length=242, Percent_Identity=26.4462809917355, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786825, Length=412, Percent_Identity=90.7766990291262, Blast_Score=780, Evalue=0.0,
Organism=Escherichia coli, GI1790045, Length=400, Percent_Identity=27.75, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787863, Length=395, Percent_Identity=24.8101265822785, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082125, Length=261, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI226510992, Length=385, Percent_Identity=24.4155844155844, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788407, Length=325, Percent_Identity=25.2307692307692, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790718, Length=371, Percent_Identity=24.5283018867925, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788075, Length=278, Percent_Identity=26.978417266187, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786552, Length=246, Percent_Identity=28.0487804878049, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081918, Length=255, Percent_Identity=27.0588235294118, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=287, Percent_Identity=27.5261324041812, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=411, Percent_Identity=25.5474452554745, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319258, Length=301, Percent_Identity=29.5681063122924, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319257, Length=298, Percent_Identity=27.8523489932886, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=281, Percent_Identity=28.8256227758007, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323729, Length=384, Percent_Identity=25.78125, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737895, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 44579; Mature: 44579

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALTYHGPHHVKVENVPDPGIEQPDDIILRVTATAICGSDLHLYRGKIPQVKHGDIFGH
CCCEECCCCCEEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCHHHCCCCCCCCCCCCCCH
EFMGEVVETGHDVKNIRKGDRVVIPFVIACGDCFFCRLQQYSACENTNDGHGAAMNKKQI
HHHHHHHHCCCHHHHHCCCCEEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PPPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLLSDDKALFLSDILPTAWQAAK
CCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHH
NAQIQQRSSVAVFGAGPVGLLTIACARLLGAEQIFVVDHHAWRLRFAEERYGAIPINFDD
CCCHHCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEHHHCCCEEEECCCC
ENDPAEKIIEQTAGHRGVDAVIDAVGFEAKGSMTETVLTNLKLEGSSGKALRQCIAAVGR
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHCC
GGVVSVPGVYAGFIHGFLFGDAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTH
CCEEECCHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YMPFEEAARGYEIFEKREEECRKVILVPGAMSAQAAQKQATGVINPMPGGVV
CCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKALTYHGPHHVKVENVPDPGIEQPDDIILRVTATAICGSDLHLYRGKIPQVKHGDIFGH
CCCEECCCCCEEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCHHHCCCCCCCCCCCCCCH
EFMGEVVETGHDVKNIRKGDRVVIPFVIACGDCFFCRLQQYSACENTNDGHGAAMNKKQI
HHHHHHHHCCCHHHHHCCCCEEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PPPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLLSDDKALFLSDILPTAWQAAK
CCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHH
NAQIQQRSSVAVFGAGPVGLLTIACARLLGAEQIFVVDHHAWRLRFAEERYGAIPINFDD
CCCHHCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEHHHCCCEEEECCCC
ENDPAEKIIEQTAGHRGVDAVIDAVGFEAKGSMTETVLTNLKLEGSSGKALRQCIAAVGR
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHCC
GGVVSVPGVYAGFIHGFLFGDAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTH
CCEEECCHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YMPFEEAARGYEIFEKREEECRKVILVPGAMSAQAAQKQATGVINPMPGGVV
CCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]