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The map label for this gene is kdpE [H]

Identifier: 29142582

GI number: 29142582

Start: 2238199

End: 2238876

Strand: Direct

Name: kdpE [H]

Synonym: t2172

Alternate gene names: 29142582

Gene position: 2238199-2238876 (Clockwise)

Preceding gene: 29142581

Following gene: 29142583

Centisome position: 46.71

GC content: 56.49

Gene sequence:

>678_bases
GTGACAAACGTTCTGATTGTTGAAGATGAACAGGCCATCCGCCGCTTTCTGCGCGCCGCGCTGGAAGGCGACGGCCTGCG
CGTGTATGAAGCTGAAACATTACAACGTGGTTTACTGGAAGCCGCCACGCGAAAGCCCGATCTGATTATTCTCGATCTCG
GCCTGCCGGACGGCGACGGAATCGATTTTATTCGCGACCTGCGTCAGTGGAGCGCAATACCGGTGATTGTCCTTTCCGCC
CGCAGCGAAGAAAGCGATAAGATTGCCGCGCTTGACGCCGGAGCTGATGATTACCTGAGCAAGCCATTCGGCATTGGCGA
GTTGCAGGCGCGTTTGCGTGTCGCGCTGCGACGGCACGCCGCCAGCCCTTGCGCCGATCCGATCGTCCGCTTTTCCGGCG
TGACGGTCGATCTCGCCGCACGGTTGATCCACCGTGGCGACGAAGAAATCCATCTGACGCCGATTGAGTTCCGCCTGCTG
GCGGTATTACTCAATAATGCCGGCAAGGTATTAACCCAACGGCAGTTATTAAACCAGGTCTGGGGCCCTAACGCCGTGGA
GCATAGCCACTATTTGCGCATCTATATGGGACATTTACGCCAGAAACTGGAACAAGATCCCACCCGCCCACGCCATTTTA
TTATCGAAACCGGAATTGGCTATCGCTTTATGCCGTGA

Upstream 100 bases:

>100_bases
GCACGCTTACCGCCTATAATCGACCGCAGGGCGGCGCCTGTTTCCGTGTGACGCTGCCGCAAGGAAAGCCACCTGAACTT
GACGATTTTCATGAGGATAT

Downstream 100 bases:

>100_bases
ATAGCTATTCATTATTTTTAAATAACTTTTAATTTTTATGTCATTTATTTTCGGCGTCGCGAATAATTATTTTCGCGGCG
ATATTATATTTTATGGAGGA

Product: DNA-binding transcriptional activator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIDFIRDLRQWSAIPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHAASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFIIETGIGYRFMP

Sequences:

>Translated_225_residues
MTNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIDFIRDLRQWSAIPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHAASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFIIETGIGYRFMP
>Mature_224_residues
TNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIDFIRDLRQWSAIPVIVLSAR
SEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHAASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLLA
VLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFIIETGIGYRFMP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=91.9642857142857, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=37.0535714285714, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=36.036036036036, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=33.6206896551724, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=205, Percent_Identity=38.0487804878049, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=201, Percent_Identity=36.318407960199, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=35.9090909090909, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=32.4324324324324, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=33.4821428571429, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=30.7017543859649, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=34.0909090909091, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=31.2775330396476, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=30.1435406698565, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=26.4705882352941, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=33.0508474576271, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=32.3529411764706, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=31.2977099236641, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25313; Mature: 25181

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCCEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
IDFIRDLRQWSAIPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHA
HHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHC
ASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFIIETGIGYRFMP
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
TNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
IDFIRDLRQWSAIPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHA
HHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHC
ASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFIIETGIGYRFMP
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]