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The map label for this gene is mntR

Identifier: 29142473

GI number: 29142473

Start: 2113821

End: 2114294

Strand: Reverse

Name: mntR

Synonym: t2052

Alternate gene names: 29142473

Gene position: 2114294-2113821 (Counterclockwise)

Preceding gene: 29142475

Following gene: 29142472

Centisome position: 44.12

GC content: 52.32

Gene sequence:

>474_bases
ATGGGTCGTCGCGCAGGTACGCCAACAACAAAAAAAGTGACGCAATTGGTGAACGTAGAAGAACACGTTGAAGGATTTCG
TCAGGTCAGAGAGGCGCATCGGCGTGAGTTGATAGACGACTACGTTGAGCTGATTTCCGATTTAATTATTGAGGTAGGGG
AAGCGCGTCAGGTGGATATGGCGGCGCGGCTCGGCGTCTCCCAGCCGACTGTGGCCAAAATGCTTAAGCGCCTGGCATCG
TTAGGATTTATTCAAATGATCCCCTGGCGCGGCGTTTTTCTGACGCCGGAAGGGGAGAAGCTGGCGCAGGAAAGCCGCGA
GCGGCATCAAATTGTCGAAAATTTTTTACTGGTATTAGGCGTAAGCCCGGAAATCGCGCGTCGTGATGCGGAAGGGATGG
AACACCATGTCAGCCAAGAGACATTAGATGCCTTTTTGGCCTTCACGCAACAGCATGGAACATCTGCAGAATGA

Upstream 100 bases:

>100_bases
TATTGCTAAAACGTTAATTTTTTGTGCCCGGACAACTCTGGTTTACAATGAGCGCTCTGTCAGCTGACGCGTTAACGCGT
CACAGAAACGAGGAAGCAAA

Downstream 100 bases:

>100_bases
ATCTGGCCTTTTTACGGGCGCTGCGGCGTGACCGTTTTTTTCAGTTGTTGATCATTGTGGGGATGGCGTTAAGCCTGTTT
GTTCCTTTTGCGCCCCGCGC

Product: manganese transport regulator MntR

Products: NA

Alternate protein names: Manganese transport regulator

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MGRRAGTPTTKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVELISDLIIEVGEARQVDMAARLGVSQPTVAKMLKRLAS
LGFIQMIPWRGVFLTPEGEKLAQESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSQETLDAFLAFTQQHGTSAE

Sequences:

>Translated_157_residues
MGRRAGTPTTKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVELISDLIIEVGEARQVDMAARLGVSQPTVAKMLKRLAS
LGFIQMIPWRGVFLTPEGEKLAQESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSQETLDAFLAFTQQHGTSAE
>Mature_156_residues
GRRAGTPTTKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVELISDLIIEVGEARQVDMAARLGVSQPTVAKMLKRLASL
GFIQMIPWRGVFLTPEGEKLAQESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSQETLDAFLAFTQQHGTSAE

Specific function: In the presence of manganese, it represses the manganese transporter mntH

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787038, Length=155, Percent_Identity=90.9677419354839, Blast_Score=288, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNTR_SALTI (P67711)

Other databases:

- EMBL:   AL627268
- EMBL:   AE014613
- RefSeq:   NP_455371.1
- RefSeq:   NP_805815.1
- ProteinModelPortal:   P67711
- SMR:   P67711
- PRIDE:   P67711
- GeneID:   1069136
- GeneID:   1247315
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2052
- KEGG:   sty:STY0876
- HOGENOM:   HBG731603
- OMA:   EARIMEE
- ProtClustDB:   PRK11050
- BioCyc:   SENT209261:T2052-MONOMER
- BioCyc:   SENT220341:STY0876-MONOMER
- GO:   GO:0005737
- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.60.10
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00529

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress; SSF47979 HTH_DtxR

EC number: NA

Molecular weight: Translated: 17728; Mature: 17596

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRAGTPTTKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVELISDLIIEVGEARQVDM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AARLGVSQPTVAKMLKRLASLGFIQMIPWRGVFLTPEGEKLAQESRERHQIVENFLLVLG
HHHCCCCCCHHHHHHHHHHHCCHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHC
VSPEIARRDAEGMEHHVSQETLDAFLAFTQQHGTSAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GRRAGTPTTKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVELISDLIIEVGEARQVDM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AARLGVSQPTVAKMLKRLASLGFIQMIPWRGVFLTPEGEKLAQESRERHQIVENFLLVLG
HHHCCCCCCHHHHHHHHHHHCCHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHC
VSPEIARRDAEGMEHHVSQETLDAFLAFTQQHGTSAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504