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The map label for this gene is dacC [H]

Identifier: 29142454

GI number: 29142454

Start: 2089966

End: 2091168

Strand: Reverse

Name: dacC [H]

Synonym: t2033

Alternate gene names: 29142454

Gene position: 2091168-2089966 (Counterclockwise)

Preceding gene: 29142456

Following gene: 29142451

Centisome position: 43.64

GC content: 53.62

Gene sequence:

>1203_bases
ATGACGCAATACGCTTCTTCCCTTCGTAGCCTCGCGGCAGGTTCGGTTCTCTTATTCCTTTTCGCTTCGCCTGTAAAGGC
AGAGGAACAAACGATCGCGCCGCCGGGCGTTGATGCGCGAGCCTGGATCTTAATGGATTACGCCAGCGGTAAAGTACTGG
CGGAAGGCAACGCCGATGAGAAACTCGACCCTGCCAGTTTGACAAAAATTATGACCAGCTACGTGGTGGGCCAGGCGCTG
AAGGCAGGCAAAATCAAGCTGACCGATATGGTGACGGTGGGCAAAGATGCCTGGGCGACGGGGAACCCGGCGCTACGTGG
GTCGTCGGTGATGTTTCTGAAGCCCGGCGATCAGGTGTCGGTTGCGGATCTTAATAAAGGCATCATCATTCAGTCAGGTA
ATGATGCCTGTATCGCGCTTGCCGACTACGTCGCCGGAAGCCAGGAGTCCTTTATCGGCCTGATGAATGCCTATGCGAAA
CGATTGGGGTTAACCAATACAACCTTCCAGACGGTACACGGCCTTGATGCGCCAGGGCAGTTCAGTACCGCTCGCGATAT
GGCGCTGCTCGGCAAGGCCTTGATTCACGATGTGCCTGACGAATACGCCATTCATAAAGAGAAAGAATTTACTTTTAATA
ATATTCGTCAGCCAAACCGCAACCGCCTGTTGTGGAGTACCAATCTGCATGTCGACGGCATGAAAACGGGGACAACGGCA
GGCGCTGGATATAACCTTGTCGCCTCCGCCACCCAGGGCGATATGCGCCTGATCTCTGTCGTGCTGGGGGCGAAAACGGA
CCGTATTCGTTTTAATGAGTCAGAAAAACTGCTGACCTGGGGTTTCCGCTTCTTTGAAACGGTCACGCCGATTAAACCTG
ACGCGACATTCGTGACGCAACGGGTCTGGTTTGGCGATAAGCGTGAGGTCAATTTGGGAGCGGGCGATGCGGGGTCTGTG
ACGATTCCGCGTGGGCAGCTTAAAAACCTGAAGGCCAGCTTTACGTTGAACGAACCACAGCTCACGGCGCCATTGAAGAA
AGGGCAGGTTGTCGGCACCATCGATTTCCAGCTTAACGGAAAATCCATTGAGCAACGCCCGTTAATGGTGATGGAAAACG
TCGAGGAGGGGGGATTTTTCAGCCGTATGTGGGATTTTGTGCTGATGAAACTCCATCAGTGGTTTGGCAGTTGGTTCTCG
TAA

Upstream 100 bases:

>100_bases
AAGTTACGGTTTCTTTAACGTCGTGAGTGCGTTATTACTCACCGCACTTATTACACGGTGGTGTGACGTGTGTTTTTGGA
ATGGATACTCGGGTGGTACT

Downstream 100 bases:

>100_bases
AATAACCCCGTTGCCGGGTGCGCGTCGCATCCGGCAAACCTGCGGTTAATACATCAGAGTAATTTGTTGCGCTTTAGCGT
AGGCCACAAAGGCCTCATCG

Product: D-alanyl-D-alanine carboxypeptidase fraction C

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQAL
KAGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGIIIQSGNDACIALADYVAGSQESFIGLMNAYAK
RLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNNIRQPNRNRLLWSTNLHVDGMKTGTTA
GAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKREVNLGAGDAGSV
TIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENVEEGGFFSRMWDFVLMKLHQWFGSWFS

Sequences:

>Translated_400_residues
MTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQAL
KAGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGIIIQSGNDACIALADYVAGSQESFIGLMNAYAK
RLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNNIRQPNRNRLLWSTNLHVDGMKTGTTA
GAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKREVNLGAGDAGSV
TIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENVEEGGFFSRMWDFVLMKLHQWFGSWFS
>Mature_399_residues
TQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALK
AGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGIIIQSGNDACIALADYVAGSQESFIGLMNAYAKR
LGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNNIRQPNRNRLLWSTNLHVDGMKTGTTAG
AGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKREVNLGAGDAGSVT
IPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENVEEGGFFSRMWDFVLMKLHQWFGSWFS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=400, Percent_Identity=92.25, Blast_Score=764, Evalue=0.0,
Organism=Escherichia coli, GI1786851, Length=397, Percent_Identity=60.7052896725441, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI87082022, Length=384, Percent_Identity=46.875, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI87082054, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43684; Mature: 43552

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWILMDYASGKVLAEGNADE
CCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEECCCCCC
KLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEE
VADLNKGIIIQSGNDACIALADYVAGSQESFIGLMNAYAKRLGLTNTTFQTVHGLDAPGQ
EEECCCCEEEECCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
FSTARDMALLGKALIHDVPDEYAIHKEKEFTFNNIRQPNRNRLLWSTNLHVDGMKTGTTA
CCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHCCCCCCCEEEEEECEEECCCCCCCCC
GAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQ
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHHCCCCCCCHHHEEE
RVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNG
EEECCCCEEEEECCCCCCCEEECCHHHCCCEEEEEECCCCEECCCCCCCEEEEEEEEECC
KSIEQRPLMVMENVEEGGFFSRMWDFVLMKLHQWFGSWFS
CCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWILMDYASGKVLAEGNADE
CHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEECCCCCC
KLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEE
VADLNKGIIIQSGNDACIALADYVAGSQESFIGLMNAYAKRLGLTNTTFQTVHGLDAPGQ
EEECCCCEEEECCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
FSTARDMALLGKALIHDVPDEYAIHKEKEFTFNNIRQPNRNRLLWSTNLHVDGMKTGTTA
CCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHCCCCCCCEEEEEECEEECCCCCCCCC
GAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQ
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHHCCCCCCCHHHEEE
RVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNG
EEECCCCEEEEECCCCCCCEEECCHHHCCCEEEEEECCCCEECCCCCCCEEEEEEEEECC
KSIEQRPLMVMENVEEGGFFSRMWDFVLMKLHQWFGSWFS
CCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]