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The map label for this gene is hcr [H]

Identifier: 29142418

GI number: 29142418

Start: 2056423

End: 2057394

Strand: Direct

Name: hcr [H]

Synonym: t1997

Alternate gene names: 29142418

Gene position: 2056423-2057394 (Clockwise)

Preceding gene: 29142417

Following gene: 29142419

Centisome position: 42.91

GC content: 55.86

Gene sequence:

>972_bases
ATGATGACGATGCCAACCTCACAATGTCCCTGGCGAATGCAGGTGCATCACATCCGTCAGGAGACGCCGGATGTATGGAC
AATTGCGCTATTATGCCATGACTACTACCCTTACCGCGCCGGGCAGTATGCGCTGGTGAGCGTGCGCAATTCAGCGGAAA
CGCTGCGCGCCTACACCCTTTCGTCTACGCCGGGCGTCAGTGAATATATCACGCTGACCGTTCGTCGGATTGAAGATGGC
ACGGGTTCACAGTGGTTGACCCATGACATCAAGCGCGGCGATTACATCTGGCTGTCTGATGCAATGGGCGATTTTACCTG
TGACGATAAAACAGAAGATAAGTTTCTGCTGCTCGCCGCCGGTTGTGGCGTAACGCCAATCATGTCGATGCGTCGCTGGC
TGGCGAAATACCGCCCGCAGGCCGACGTGCAGGTCATCTTTAACGTCCGTTCGCCGGATGATGTGATTTTTGCCGACGAG
TGGCGACAGTATCCGGTCACGCTAGTGGCGGAAAATCATGCCACGGAAGGTTTTATCGCGGGCCGTCTGACCACGGAATT
GTTACAGCGCGTACCGGATTTGGCATCGCGCACTATCATGACCTGCGGCCCGGCGCCCTATATGGATTTCGTTGAACAGG
GAGTGAAAGCGCTTGGCGTAACGCACTTCTTTAAAGAGAAGTTCTTCACGCCGGTGGCGGAAACGGCAACCAGCGGCCTG
AAATTCACCAAACTACAGCCAGCGCAGGAATTTTATGCCCCAATCGGTACGACGCTGCTGGAGGCGCTGGAGAGTAATAA
AGTACCGGTTGCCGCTGCCTGTCGGGCAGGTGTTTGCGGCTGCTGTAAAACCAAAGTCGTTTCCGGCGACTATACGGTGA
GCAGCACCATGACGCTGAGCGAGGCGGAGATTGCCGAAGGTTACGTACTGGCCTGCTCCTGCCATCCGCAGGGCGATCTT
GTTCTCGCATAA

Upstream 100 bases:

>100_bases
CGCCGGATTTGCTGGCTATCCTCAACGAGAAGTTCGGTCTGCGCTCCGTGACCACTGTTGAAGAAGACATGAAGCAATTG
CTGAGCGCGTAAGGAGGCCA

Downstream 100 bases:

>100_bases
TCGGTAAACGTTCCATCGTAGGCCCGGTAAGCGTCAGCGCCACCGGGCGATTTACCACTCGCTTCATCCTTTCGCCCCTC
TCTCCGCCAAAGAAAAACGT

Product: NADH-dependent HCP oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTLSSTPGVSEYITLTVRRIEDG
TGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAAGCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADE
WRQYPVTLVAENHATEGFIAGRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTHFFKEKFFTPVAETATSGL
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLSEAEIAEGYVLACSCHPQGDL
VLA

Sequences:

>Translated_323_residues
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTLSSTPGVSEYITLTVRRIEDG
TGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAAGCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADE
WRQYPVTLVAENHATEGFIAGRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTHFFKEKFFTPVAETATSGL
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLSEAEIAEGYVLACSCHPQGDL
VLA
>Mature_323_residues
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTLSSTPGVSEYITLTVRRIEDG
TGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAAGCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADE
WRQYPVTLVAENHATEGFIAGRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTHFFKEKFFTPVAETATSGL
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLSEAEIAEGYVLACSCHPQGDL
VLA

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=322, Percent_Identity=89.1304347826087, Blast_Score=611, Evalue=1e-176,
Organism=Escherichia coli, GI1787658, Length=342, Percent_Identity=26.9005847953216, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788104, Length=325, Percent_Identity=26.7692307692308, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35870; Mature: 35870

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTL
CCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCEEEEEECCCHHHEEEEEE
SSTPGVSEYITLTVRRIEDGTGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAA
CCCCCCCCEEEEEEEEECCCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEE
GCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADEWRQYPVTLVAENHATEGFIA
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCEEEEECCCCCCCEEH
GRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTHFFKEKFFTPVAETATSGL
HHHHHHHHHHCHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCE
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLS
EEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCCEEEECEEEEC
EAEIAEGYVLACSCHPQGDLVLA
HHHHCCCEEEEEEECCCCCEEEC
>Mature Secondary Structure
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTL
CCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCEEEEEECCCHHHEEEEEE
SSTPGVSEYITLTVRRIEDGTGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAA
CCCCCCCCEEEEEEEEECCCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEE
GCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADEWRQYPVTLVAENHATEGFIA
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCEEEEECCCCCCCEEH
GRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTHFFKEKFFTPVAETATSGL
HHHHHHHHHHCHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCE
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLS
EEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCCEEEECEEEEC
EAEIAEGYVLACSCHPQGDLVLA
HHHHCCCEEEEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]