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The map label for this gene is aroA [H]

Identifier: 29142379

GI number: 29142379

Start: 2006649

End: 2007932

Strand: Reverse

Name: aroA [H]

Synonym: t1956

Alternate gene names: 29142379

Gene position: 2007932-2006649 (Counterclockwise)

Preceding gene: 29142380

Following gene: 29142378

Centisome position: 41.9

GC content: 53.82

Gene sequence:

>1284_bases
ATGGAATCCCTGACGTTACAACCCATCGCGCGGGTCGATGGCGCCATTAATTTACCTGGCTCCAAAAGTGTTTCAAACCG
TGCTTTGCTCCTGGCGGCTTTAGCTTGTGGTAAAACCGTTCTGACGAATCTGCTGGATAGCGATGACGTCCGCCATATGC
TCAATGCCCTGAGCGCGTTGGGGATCAATTACACCCTTTCTGCCGATCGCACCCGCTGTGATATCACGGGTAATGGCGGC
CCATTACGCGCGTCAGGCACTCTGGAACTGTTTCTCGGTAATGCCGGAACCGCGATGCGTCCGTTAGCGGCAGCGCTATG
TCTGGGGCAAAATGAGATAGTGTTAACCGGCGAACCGCGTATGAAAGAGCGTCCGATAGGCCATCTGGTCGATTCGCTGC
GTCAGGGTGGGGCGAATATTGATTACCTGGAGCAGGAAAACTATCCGCCCCTGCGTCTGCGCGGCGGTTTTATCGGCGGC
GACATTGAGGTTGATGGTAGCGTTTCCAGCCAGTTCCTGACCGCTCTGCTGATGACGGCGCCGCTGGCGCCTGAAGACAC
AATTATTCGCGTTAAAGGCGAACTGGTATCAAAACCTTACATCGATATCACGCTAAATTTAATGAAAACCTTTGGCGTGG
AGATAGCGAACCATCACTACCAACAATTTGTCGTGAAGGGCGGTCAACAGTATCACTCTCCAGGTCGCTATCTGGTCGAG
GGCGATGCCTCGTCAGCGTCCTATTTTCTCGCCGCTGGGGCGATAAAAGGCGGCACGGTAAAAGTGACCGGGATTGGCCG
CAAAAGTATGCAGGGCGATATTCGTTTTGCCGATGTGCTGGAGAAAATGGGCGCGACCATTACCTGGGGCGATGATTTTA
TTGCCTGCACGCGCGGCGAATTGCACGCCATAGATATGGATATGAACCATATTCCGGATGCGGCGATGACGATTGCCACC
ACGGCGTTGTTTGCGAAAGGAACCACGACGTTGCGCAATATTTATAACTGGCGAGTGAAAGAAACCGATCGCCTGTTCGC
GATGGCGACCGAGCTACGTAAAGTGGGCGCTGAAGTCGAAGAAGGGCACGACTATATTCGTATCACGCCGCCGGCGAAGC
TCCAACACGCGGATATTGGCACGTACAACGACCACCGTATGGCGATGTGTTTCTCACTGGTCGCACTGTCCGATACGCCA
GTCACGATCCTGGACCCTAAATGTACCGCAAAAACGTTCCCTGATTATTTCGAACAACTGGCGCGGATGAGTACGCCTGC
CTAA

Upstream 100 bases:

>100_bases
ATGATCGATTTTGAGCGCCGCCACGGCTAATACGTTTCTTTTTTCATCCCCACGGCCAGTCTGTGGGGTTTTTATTTCTG
TTTTTTGAGAGTTGAGTTTC

Downstream 100 bases:

>100_bases
TTCTTCTGTTGCGCCAGTCGACGGGCTGGCGCGTCGAGTCCGTATTCGCACTATTTTTATAATTATGACTAATGCTAATT
TGTTGGTGATTTAACACATT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGG
PLRASGTLELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGG
DIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIAT
TALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARMSTPA

Sequences:

>Translated_427_residues
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGG
PLRASGTLELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGG
DIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIAT
TALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARMSTPA
>Mature_427_residues
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGG
PLRASGTLELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGG
DIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIAT
TALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARMSTPA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=427, Percent_Identity=89.6955503512881, Blast_Score=781, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320332, Length=446, Percent_Identity=39.6860986547085, Blast_Score=262, Evalue=9e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46220; Mature: 46220

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSAL
CCCCCCCHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GINYTLSADRTRCDITGNGGPLRASGTLELFLGNAGTAMRPLAAALCLGQNEIVLTGEPR
CCEEEEECCCEEEEEECCCCEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCC
MKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGGDIEVDGSVSSQFLTALLMTA
CCCCCHHHHHHHHHHCCCCCCEECCCCCCCEEEECCEECCCEEECCCHHHHHHHHHHHHC
PLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
CCCCCCCEEEEECCCCCCCEEEEEHEEHHHHCHHHHHHHHHHHHHCCCHHHCCCCCEEEE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGE
CCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCEEEECCCC
LHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCEECCCHHHHHHHHHHHHHCCHHH
EGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
CCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHH
ARMSTPA
HHHCCCC
>Mature Secondary Structure
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSAL
CCCCCCCHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GINYTLSADRTRCDITGNGGPLRASGTLELFLGNAGTAMRPLAAALCLGQNEIVLTGEPR
CCEEEEECCCEEEEEECCCCEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCC
MKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGGDIEVDGSVSSQFLTALLMTA
CCCCCHHHHHHHHHHCCCCCCEECCCCCCCEEEECCEECCCEEECCCHHHHHHHHHHHHC
PLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
CCCCCCCEEEEECCCCCCCEEEEEHEEHHHHCHHHHHHHHHHHHHCCCHHHCCCCCEEEE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGE
CCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCEEEECCCC
LHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCEECCCHHHHHHHHHHHHHCCHHH
EGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
CCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHH
ARMSTPA
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA