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The map label for this gene is sseC [H]

Identifier: 29141729

GI number: 29141729

Start: 1339403

End: 1340857

Strand: Direct

Name: sseC [H]

Synonym: t1268

Alternate gene names: 29141729

Gene position: 1339403-1340857 (Clockwise)

Preceding gene: 29141728

Following gene: 29141730

Centisome position: 27.95

GC content: 45.5

Gene sequence:

>1455_bases
ATGAATCGAATTCACAGTAATAGCGATAGCGCCGCAGGAGTAACCGCCTTAACACATCATCACTTAAGCAATGTCAGTTG
CGTTTCCTCGGGTTCGCTGGGAAAGCGCCAGCATCGTGTGAATTCTACTTTTGGCGATGGCAACGCCGCGTGTCTGCTAT
CCGGGAAAATTAGTCTTCAGGAGGCAAGCAATGCGTTGAAGCAACTGCTTGATGCCGTACCCGGAAATCATAAGCGTCCA
TCATTGCCTGACTTTTTGCAGACCAATCCCGCGGTTTTATCAATGATGATGACGTCATTAATACTCAACGTCTTTGGTAA
TAACGCTCAATCGTTATGCCAACAGCTTGAGCGGGCAACTGAGGTGCAAAATGCATTACGTAATAAGCAGGTAAAGGAGT
ATCAGGAGCAGATCCAGAAAGCGATAGAGCAGGAGGATAAAGCGCGTAAAGCGGGTATTTTTGGCGCTATTTTTGACTGG
ATTACCGGCATATTTGAAACCGTGATTGGCGCCTTAAAAGTTGTGGAAGGTTTTCTGTCCGGTAATCCCGCAGAAATGGC
TAGCGGCGTAGCTTATATGGCCGCAGGTTGTGCAGGAATGGTTAAAGCCGGAGCCGAAACGGCAATGATGTGCGGTGCTG
ACCACGATACCTGTCAGGCGATTATTGACGTGACAAGTAAGATTCAATTTGGTTGTGAAGCCGTCGCGCTGGCACTGGAT
GTTTTCCAGATTGGCCGTGCTTTTATGGCGACGAGAGGTTTATCTGGCGCAGCTGCAAAAGTGCTTGACTCCGGTTTTGG
CGAGGAAATGGTTGAGCGTATGGTTGGTGCAGGGGAAGCAGAAATAGAGGCGTTGGCTGAAAAGTTTGGCGAAGAAGTGA
GCGAAAGTTTTTCCAAACAATTTGAGCCGCTTGAACGTGAAATGGTTTCGCCGGGCGAGATGGAAGAGGAGTCTGCCGAA
TTTTCTCGTAACGTAGAAAAAAATATGACAAAAAATGCGGGAAAAAGTTTTACGAAAGAGGGGGTGAAAGCCATGGCAAA
AGAAGCGGTAAAAGAAGCCCTGGAAAAATATGCGCAAGAAGGGGAAAAGTTTCTGTTAAAAAATTTTCGTAATAAAGTTC
TCTTCAATATGTTCAAAAAAATCCTGTATGCCTTACTGAGGGATTGTTCATTTAAAGGCTTACAGGCTATCAGATGTGCA
ACCGAGGGTGCCAATCAGATGAATACTGGCATGGTTAACACAGAAAAAGCGAAGCTTGAAAAGAAAATAGAGCAATTAAT
AACTCAGCAACGGTTTCTGGATTTCATAATGCAACAAACGGATGACCAAAAAAAGATAGAACAAAAACGCTTAGAGGGGC
TTTATAAAGGTAGCGGTGCCGCGCTTAGAGGTGTATTAGATACCATTGATCACTATAGTAGCGTTCAGGCGAGAATAGCT
GGCTGGCGCGCTTAA

Upstream 100 bases:

>100_bases
TAAAAGCCGTGGTGCGTATTTGCGGCGAGGTCAGTGAACATCAAATCCTCCGACTACGTGCAGAAAAGATGTTACAGCAG
CTTTCTGACAGGAGCTAAAA

Downstream 100 bases:

>100_bases
TCTGAGGATAAAAATATGGAAGCGAGTAACGTAGCACTGGTATTACCAGCGCCTTCCTTGTTAACGCCTTCTTCCACTCC
ATCTCCCTCCGGGGAGGGAA

Product: pathogenicity island effector protein

Products: NA

Alternate protein names: Secretion system effector C [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTFGDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRP
SLPDFLQTNPAVLSMMMTSLILNVFGNNAQSLCQQLERATEVQNALRNKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDW
ITGIFETVIGALKVVEGFLSGNPAEMASGVAYMAAGCAGMVKAGAETAMMCGADHDTCQAIIDVTSKIQFGCEAVALALD
VFQIGRAFMATRGLSGAAAKVLDSGFGEEMVERMVGAGEAEIEALAEKFGEEVSESFSKQFEPLEREMVSPGEMEEESAE
FSRNVEKNMTKNAGKSFTKEGVKAMAKEAVKEALEKYAQEGEKFLLKNFRNKVLFNMFKKILYALLRDCSFKGLQAIRCA
TEGANQMNTGMVNTEKAKLEKKIEQLITQQRFLDFIMQQTDDQKKIEQKRLEGLYKGSGAALRGVLDTIDHYSSVQARIA
GWRA

Sequences:

>Translated_484_residues
MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTFGDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRP
SLPDFLQTNPAVLSMMMTSLILNVFGNNAQSLCQQLERATEVQNALRNKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDW
ITGIFETVIGALKVVEGFLSGNPAEMASGVAYMAAGCAGMVKAGAETAMMCGADHDTCQAIIDVTSKIQFGCEAVALALD
VFQIGRAFMATRGLSGAAAKVLDSGFGEEMVERMVGAGEAEIEALAEKFGEEVSESFSKQFEPLEREMVSPGEMEEESAE
FSRNVEKNMTKNAGKSFTKEGVKAMAKEAVKEALEKYAQEGEKFLLKNFRNKVLFNMFKKILYALLRDCSFKGLQAIRCA
TEGANQMNTGMVNTEKAKLEKKIEQLITQQRFLDFIMQQTDDQKKIEQKRLEGLYKGSGAALRGVLDTIDHYSSVQARIA
GWRA
>Mature_484_residues
MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTFGDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRP
SLPDFLQTNPAVLSMMMTSLILNVFGNNAQSLCQQLERATEVQNALRNKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDW
ITGIFETVIGALKVVEGFLSGNPAEMASGVAYMAAGCAGMVKAGAETAMMCGADHDTCQAIIDVTSKIQFGCEAVALALD
VFQIGRAFMATRGLSGAAAKVLDSGFGEEMVERMVGAGEAEIEALAEKFGEEVSESFSKQFEPLEREMVSPGEMEEESAE
FSRNVEKNMTKNAGKSFTKEGVKAMAKEAVKEALEKYAQEGEKFLLKNFRNKVLFNMFKKILYALLRDCSFKGLQAIRCA
TEGANQMNTGMVNTEKAKLEKKIEQLITQQRFLDFIMQQTDDQKKIEQKRLEGLYKGSGAALRGVLDTIDHYSSVQARIA
GWRA

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells [H]

COG id: COG5613

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted via type III secretion system 2 (SPI-2 TTSS). After secretion, localizes mainly on the surface of the bacterial cell [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006972 [H]

Pfam domain/function: PF04888 SseC [H]

EC number: NA

Molecular weight: Translated: 52817; Mature: 52817

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9786193; 9786194; 11677609 [H]