Click here to switch to the map view.

The map label for this gene is sufD [H]

Identifier: 29141704

GI number: 29141704

Start: 1309599

End: 1310870

Strand: Direct

Name: sufD [H]

Synonym: t1240

Alternate gene names: 29141704

Gene position: 1309599-1310870 (Clockwise)

Preceding gene: 29141703

Following gene: 29141705

Centisome position: 27.33

GC content: 53.54

Gene sequence:

>1272_bases
ATGGCTGGCTTACCGAACAGCAGTAAAGCGCTACAGCAATGGCAGCATCTCTTTGAAGAAAAAGGAGAAATTCGAACTGA
GCAGGCAAGACAACATTTCCAACAGATGTTACGTCTGGGATTGCCGACGCGTAAACATGAAGACTGGAAATACACGCCGC
TGGAGGGCTTAACCCATAGCCAGTTTATCCAGCAGTGTGCGACTATCAGCGCCGCCCAGCGTGATGCGCTGGCGCTGCAA
ATCGATGCCGTGCGGCTGGTGTTTGTCGACGGACGGTTTATGCCAGAGCTCAGTGATAGCACGCAAAACAGCGGATTTGA
CGTTAGCGTCAGAGATGAGCGCCAGACGCTTGCCGCGCCGGTACATCCCGAGGTTTTTCTGCATCTGACGGAAAGCCTGG
CGCAATGTGTCACGTATATACAGGTACGGCGAAATCAGCGTCCGACCAGGCCGCTACTGTTAATGCATATCACGCAGGGC
GTGGATAGCGACGAGCTGAATACCGCGCATTATCGCCACCATCTGACGCTGGCAGAAGGCGCGGAAGCGACGGTTATTGA
GCATTATGTCAGCCTTACAGCGGCAAAACATTTTACCGGCGCGCGTCTGACGATGAACGTTGCAGACAATGCGCAACTGC
GTCATATCAAACTGGCGTTTGAAAATGCGTCCAGCTATCACTTTGCGCATAACGATCTTCTGCTGGCGACAGACGCCTCG
GCGTTTAGCCACAGTTTTCTGCTGGGCGCCGCAGTACTACGTCACCACAGCAGCTCACAACTGAATGGCGAAAACGCGAC
GCTTCGACTGAATAGTCTGGCGATGCCAGTGAAAAATGAAGTCTGCGATACGCGGACATGGCTGGAACATAACAAAGGCT
ACTGTAACAGCCGCCAGTTGCACAAGACCATCGTCAGCGACAAAGGACGCGCGGTCTTTAATGGCCTGATTAACGTGGCG
CAACACTCCATTAAAACCGACGGCCAGATGACCAATAATAACCTATTGTTGGGGAAACTGGCTGAAGTCGATACCAAACC
GCAATTAGAGATCTATGCCGATGACGTGAAGTGCAGCCACGGCGCGACGATCGGGCGTATTGACGATGAGCAGATGTTTT
ATCTGCAATCACGCGGCATCAGGCAGCAGGAGGCGCGGCACATGATTCTTTACGCGTTTGCCGCAGAGTTAACGGAAGCT
ATCCATGATAGCGCCCTTAAACAGCAGGTGCTGGCGCGAATCGGCCAGCGACTGCCCGGAGGCCTGGTATGA

Upstream 100 bases:

>100_bases
CTGGACTACATCAAGCCTGATTACGTCCATGTCCTCTATCAGGGGCGAATTGTCCGTTCCGGCGATTTTACTCTGGTCAA
ACAACTGGAGGAGCAGGGTT

Downstream 100 bases:

>100_bases
CATTTCCTGTAGAAAAAGTACGGGCGGATTTTCCCATACTGCAGCGTGAAGTTAACGGCCTGCCGCTGGCTTACCTGGAC
AGCGCAGCCAGCGCTCAAAA

Product: cysteine desulfurase activator complex subunit SufD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MAGLPNSSKALQQWQHLFEEKGEIRTEQARQHFQQMLRLGLPTRKHEDWKYTPLEGLTHSQFIQQCATISAAQRDALALQ
IDAVRLVFVDGRFMPELSDSTQNSGFDVSVRDERQTLAAPVHPEVFLHLTESLAQCVTYIQVRRNQRPTRPLLLMHITQG
VDSDELNTAHYRHHLTLAEGAEATVIEHYVSLTAAKHFTGARLTMNVADNAQLRHIKLAFENASSYHFAHNDLLLATDAS
AFSHSFLLGAAVLRHHSSSQLNGENATLRLNSLAMPVKNEVCDTRTWLEHNKGYCNSRQLHKTIVSDKGRAVFNGLINVA
QHSIKTDGQMTNNNLLLGKLAEVDTKPQLEIYADDVKCSHGATIGRIDDEQMFYLQSRGIRQQEARHMILYAFAAELTEA
IHDSALKQQVLARIGQRLPGGLV

Sequences:

>Translated_423_residues
MAGLPNSSKALQQWQHLFEEKGEIRTEQARQHFQQMLRLGLPTRKHEDWKYTPLEGLTHSQFIQQCATISAAQRDALALQ
IDAVRLVFVDGRFMPELSDSTQNSGFDVSVRDERQTLAAPVHPEVFLHLTESLAQCVTYIQVRRNQRPTRPLLLMHITQG
VDSDELNTAHYRHHLTLAEGAEATVIEHYVSLTAAKHFTGARLTMNVADNAQLRHIKLAFENASSYHFAHNDLLLATDAS
AFSHSFLLGAAVLRHHSSSQLNGENATLRLNSLAMPVKNEVCDTRTWLEHNKGYCNSRQLHKTIVSDKGRAVFNGLINVA
QHSIKTDGQMTNNNLLLGKLAEVDTKPQLEIYADDVKCSHGATIGRIDDEQMFYLQSRGIRQQEARHMILYAFAAELTEA
IHDSALKQQVLARIGQRLPGGLV
>Mature_422_residues
AGLPNSSKALQQWQHLFEEKGEIRTEQARQHFQQMLRLGLPTRKHEDWKYTPLEGLTHSQFIQQCATISAAQRDALALQI
DAVRLVFVDGRFMPELSDSTQNSGFDVSVRDERQTLAAPVHPEVFLHLTESLAQCVTYIQVRRNQRPTRPLLLMHITQGV
DSDELNTAHYRHHLTLAEGAEATVIEHYVSLTAAKHFTGARLTMNVADNAQLRHIKLAFENASSYHFAHNDLLLATDASA
FSHSFLLGAAVLRHHSSSQLNGENATLRLNSLAMPVKNEVCDTRTWLEHNKGYCNSRQLHKTIVSDKGRAVFNGLINVAQ
HSIKTDGQMTNNNLLLGKLAEVDTKPQLEIYADDVKCSHGATIGRIDDEQMFYLQSRGIRQQEARHMILYAFAAELTEAI
HDSALKQQVLARIGQRLPGGLV

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI1787971, Length=421, Percent_Identity=78.3847980997625, Blast_Score=683, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000825
- InterPro:   IPR011542 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 47498; Mature: 47367

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLPNSSKALQQWQHLFEEKGEIRTEQARQHFQQMLRLGLPTRKHEDWKYTPLEGLTHS
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
QFIQQCATISAAQRDALALQIDAVRLVFVDGRFMPELSDSTQNSGFDVSVRDERQTLAAP
HHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHCCC
VHPEVFLHLTESLAQCVTYIQVRRNQRPTRPLLLMHITQGVDSDELNTAHYRHHLTLAEG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHEEEEECCC
AEATVIEHYVSLTAAKHFTGARLTMNVADNAQLRHIKLAFENASSYHFAHNDLLLATDAS
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEECCCCEEEECCCEEEEECCH
AFSHSFLLGAAVLRHHSSSQLNGENATLRLNSLAMPVKNEVCDTRTWLEHNKGYCNSRQL
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHH
HKTIVSDKGRAVFNGLINVAQHSIKTDGQMTNNNLLLGKLAEVDTKPQLEIYADDVKCSH
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHCCCCCCCEEEEECCEECCC
GATIGRIDDEQMFYLQSRGIRQQEARHMILYAFAAELTEAIHDSALKQQVLARIGQRLPG
CCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLV
CCC
>Mature Secondary Structure 
AGLPNSSKALQQWQHLFEEKGEIRTEQARQHFQQMLRLGLPTRKHEDWKYTPLEGLTHS
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
QFIQQCATISAAQRDALALQIDAVRLVFVDGRFMPELSDSTQNSGFDVSVRDERQTLAAP
HHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHCCC
VHPEVFLHLTESLAQCVTYIQVRRNQRPTRPLLLMHITQGVDSDELNTAHYRHHLTLAEG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHEEEEECCC
AEATVIEHYVSLTAAKHFTGARLTMNVADNAQLRHIKLAFENASSYHFAHNDLLLATDAS
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEECCCCEEEECCCEEEEECCH
AFSHSFLLGAAVLRHHSSSQLNGENATLRLNSLAMPVKNEVCDTRTWLEHNKGYCNSRQL
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHH
HKTIVSDKGRAVFNGLINVAQHSIKTDGQMTNNNLLLGKLAEVDTKPQLEIYADDVKCSH
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHCCCCCCCEEEEECCEECCC
GATIGRIDDEQMFYLQSRGIRQQEARHMILYAFAAELTEAIHDSALKQQVLARIGQRLPG
CCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]