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The map label for this gene is cheW [H]

Identifier: 29141439

GI number: 29141439

Start: 1044357

End: 1044860

Strand: Direct

Name: cheW [H]

Synonym: t0957

Alternate gene names: 29141439

Gene position: 1044357-1044860 (Clockwise)

Preceding gene: 29141438

Following gene: 29141440

Centisome position: 21.79

GC content: 52.98

Gene sequence:

>504_bases
ATGACCGGTATGAGTAATGTAAGCAAACTGGCCGGCGAGCCGTCAGGTCAGGAATTCCTGGTGTTTACACTGGGAAATGA
AGAGTACGGCATCGATATCCTGAAAGTGCAGGAGATCCGTGGCTATGACCAGGTGACGCGCATCGCCAATACACCGGCCT
TTATAAAAGGGGTGACTAACCTGCGCGGCGTGATTGTCCCCATTGTCGATCTGCGCGTGAAATTCTGCGAAGGCGACGTT
GAGTATGATGACAATACGGTAGTGATCGTACTGAATCTGGGGCAACGTGTCGTCGGGATAGTGGTAGGCGGCGTGTCTGA
CGTACTGTCGTTAACGGCGGAACAGATCCGTCCGGCGCCAGAATTTGCCGTGACCTTGTCAACAGAATATTTGACGGGAT
TGGGCGCGCTCGGCGAGCGTATGCTGATTCTGGTGAATATCGAAAAACTGCTTAACAGCGAAGAGATGGCGCTGCTGGAT
ATCGCAGCATCACACGTCGCGTAA

Upstream 100 bases:

>100_bases
GCAGCGTCGCGCTGATTGTTGATGTTTCCGCATTGCAGGGTTTAAACCGCGAACAACGTATGGCGATCACAGCCGCCTGA
TTGAGTGAGAAGGGAATAAT

Downstream 100 bases:

>100_bases
TAACGTTGCCGGATGGCGTCGCGCCATCCGGCAATATTCACCGTTATGCTTCCGCCAGCGGTGAGAGTGCCTCTTCATCG
CCCGCGCCCAGCCCCTGCAT

Product: purine-binding chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MTGMSNVSKLAGEPSGQEFLVFTLGNEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRVKFCEGDV
EYDDNTVVIVLNLGQRVVGIVVGGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGERMLILVNIEKLLNSEEMALLD
IAASHVA

Sequences:

>Translated_167_residues
MTGMSNVSKLAGEPSGQEFLVFTLGNEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRVKFCEGDV
EYDDNTVVIVLNLGQRVVGIVVGGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGERMLILVNIEKLLNSEEMALLD
IAASHVA
>Mature_166_residues
TGMSNVSKLAGEPSGQEFLVFTLGNEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRVKFCEGDVE
YDDNTVVIVLNLGQRVVGIVVGGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGERMLILVNIEKLLNSEEMALLDI
AASHVA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=167, Percent_Identity=91.6167664670659, Blast_Score=305, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17991; Mature: 17860

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMSNVSKLAGEPSGQEFLVFTLGNEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTN
CCCCHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHCC
LRGVIVPIVDLRVKFCEGDVEYDDNTVVIVLNLGQRVVGIVVGGVSDVLSLTAEQIRPAP
CCEEEEEHEEEEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHCCCCC
EFAVTLSTEYLTGLGALGERMLILVNIEKLLNSEEMALLDIAASHVA
CEEEEEEHHHHHHHHCCCCEEEEEEEHHHHCCCCCCHHEEHHHHHCC
>Mature Secondary Structure 
TGMSNVSKLAGEPSGQEFLVFTLGNEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTN
CCCHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHCC
LRGVIVPIVDLRVKFCEGDVEYDDNTVVIVLNLGQRVVGIVVGGVSDVLSLTAEQIRPAP
CCEEEEEHEEEEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHCCCCC
EFAVTLSTEYLTGLGALGERMLILVNIEKLLNSEEMALLDIAASHVA
CEEEEEEHHHHHHHHCCCCEEEEEEEHHHHCCCCCCHHEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]