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The map label for this gene is cheA [H]

Identifier: 29141438

GI number: 29141438

Start: 1042321

End: 1044336

Strand: Direct

Name: cheA [H]

Synonym: t0956

Alternate gene names: 29141438

Gene position: 1042321-1044336 (Clockwise)

Preceding gene: 29141437

Following gene: 29141439

Centisome position: 21.75

GC content: 54.96

Gene sequence:

>2016_bases
GTGAGCATGGATATTAGCGATTTTTATCAGACATTTTTTGATGAAGCTGACGAGCTGTTGGCTGATATGGAGCAGCATCT
GCTGGATTTGGTGCCGGAATCCCCGGACGCTGAACAACTGAACGCCATTTTTCGCGCGGCGCACTCCATTAAAGGCGGCG
CGGGCACATTCGGCTTCACTATTCTGCAGGAAACCACACATTTAATGGAAAACCTGCTGGATGAAGCCCGACGCGGTGAA
ATGCAGCTCAATACCGACATTATCAACCTGTTTTTGGAAACGAAAGATATTATGCAGGAACAGCTCGACGCCTATAAAAA
CTCCGAAGAGCCGGATGCCGCAAGCTTCGAATATATCTGCAATGCGCTACGCCAGTTGGCGCTGGAGGCGAAAGGCGAAA
CCACGCCGGCGGTCGTAGAAACCGCGGCACTAAGTGCGGCGATCCAGGAAGAGAGCGTAGCCGAAACCGAATCGCCTCGT
GACGAGAGTAAACTGCGCATTGTACTTTCACGGTTGAAAGCCAATGAGGTCGATCTGCTTGAAGAAGAGTTGGGCAATCT
GGCTACTCTGACGGATGTCGTTAAGGGGGCGGATTCACTGTCGGCAACTCTGGATGGCAGCGTCGCGGAAGATGACATTG
TCGCGGTGCTCTGTTTTGTCATCGAGGCCGATCAGATCGCTTTTGAAAAAGTGGTCACCGCGCCGGTTGAAAAAGCGCAA
GAGAAAACCGAGGTAGCACCGGTAGCGTCTCCGGCAGTCGTTGCGCCAGCCGCCAAAAGCGCGGCCCATGAACATCATGC
GGGGCGTGAAAAACCTGCGCGTGAACGCGAGTCCACCAGCATTCGCGTGGCGGTAGAGAAAGTGGATCAGCTCATAAACC
TGGTCGGCGAGTTAGTGATTACCCAGTCAATGTTGGCCCAGCGTTCTAACGAGCTGGACCCGGTAAACCACGGCGATCTC
ATTACCAGTATGGGGCAGTTACAACGTAACGCCCGCGACTTACAAGAGTCGGTGATGTCGATTCGTATGATGCCTATGGA
GTACGTCTTCAGCCGTTTCCCGCGTCTGGTACGCGATTTAGCGGGCAAACTGGGCAAGCAGGTAGAGCTGACGCTGGTGG
GGAGCTCCACTGAACTTGATAAAAGCCTGATCGAACGCATTATCGACCCGCTGACGCACCTGGTGCGCAACAGTCTCGAC
CACGGGATTGAAATGCCGGAAAAACGCCTTGAGGCGGGGAAAAATGTTGTCGGCAATCTGATCCTTTCTGCAGAACATCA
GGGCGGGAATATTTGTATTGAAGTGACCGATGACGGCGCGGGGCTTAACCGTGAGCGTATCCTGGCGAAGGCCATGTCGC
AGGGGATGGCGGTGAATGAAAACATGACCGACGATGAAGTAGGCATGTTGATCTTCGCGCCGGGATTCTCAACTGCGGAA
CAGGTCACGGATGTCTCCGGTCGCGGCGTTGGCATGGATGTGGTGAAACGTAACATTCAGGAGATGGGCGGTCACGTTGA
GATCCAGTCAAAACAAGGCTCCGGCACCACGATTCGTATTCTGCTGCCGCTGACGCTGGCCATCCTCGATGGGATGTCGG
TTCGCGTGGCGGGGGAAGTTTTTATCCTGCCGTTAAATGCGGTGATGGAGTCGCTGCAACCGCGTGAAGAGGATCTTCAT
CCGCTGGCGGGCGGCGAACGGGTTCTGGAAGTTCGCGGCGAGTATTTGCCGCTGGTCGAATTGTGGAAAGTGTTTGACGT
GGACGGGGCGAAAACCGAATCCACGCAGGGCATTGTTGTGATCCTGCAAAGCGCGGGACGCCGTTACGCGCTGCTGGTCG
ATCAGCTCATCGGTCAGCACCAGGTGGTGGTCAAAAATCTGGAAAGCAATTATCGCAAGGTACCGGGGATTTCCGCCGCG
ACGATCCTGGGCGACGGCAGCGTCGCGCTGATTGTTGATGTTTCCGCATTGCAGGGTTTAAACCGCGAACAACGTATGGC
GATCACAGCCGCCTGA

Upstream 100 bases:

>100_bases
GCTGAAAGCCAGAATGAGCCGGTAAGTGTATTACAACAGCCTGCGGCAGCCCCGCCGGCAAGCGTACCCACATCGCCAAA
AGCGGAACCGAGGTGATAGC

Downstream 100 bases:

>100_bases
TTGAGTGAGAAGGGAATAATATGACCGGTATGAGTAATGTAAGCAAACTGGCCGGCGAGCCGTCAGGTCAGGAATTCCTG
GTGTTTACACTGGGAAATGA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSMDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGE
MQLNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPR
DESKLRIVLSRLKANEVDLLEEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVTAPVEKAQ
EKTEVAPVASPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVNHGDL
ITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLD
HGIEMPEKRLEAGKNVVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAE
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFILPLNAVMESLQPREEDLH
PLAGGERVLEVRGEYLPLVELWKVFDVDGAKTESTQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAA
TILGDGSVALIVDVSALQGLNREQRMAITAA

Sequences:

>Translated_671_residues
MSMDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGE
MQLNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPR
DESKLRIVLSRLKANEVDLLEEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVTAPVEKAQ
EKTEVAPVASPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVNHGDL
ITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLD
HGIEMPEKRLEAGKNVVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAE
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFILPLNAVMESLQPREEDLH
PLAGGERVLEVRGEYLPLVELWKVFDVDGAKTESTQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAA
TILGDGSVALIVDVSALQGLNREQRMAITAA
>Mature_670_residues
SMDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGEM
QLNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPRD
ESKLRIVLSRLKANEVDLLEEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVTAPVEKAQE
KTEVAPVASPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVNHGDLI
TSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDH
GIEMPEKRLEAGKNVVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAEQ
VTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFILPLNAVMESLQPREEDLHP
LAGGERVLEVRGEYLPLVELWKVFDVDGAKTESTQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
ILGDGSVALIVDVSALQGLNREQRMAITAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=672, Percent_Identity=84.6726190476191, Blast_Score=1131, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73050; Mature: 72919

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
ILQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYIC
HHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
NALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPRDESKLRIVLSRLKANEVDLL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHH
EEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVTAPVEKAQ
HHHHCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKTEVAPVASPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVI
HHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
TQSMLAQRSNELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIEMPEKRLEAGKNVVGNL
HHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHH
ILSAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAE
HEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHH
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEV
HHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEECEE
FILPLNAVMESLQPREEDLHPLAGGERVLEVRGEYLPLVELWKVFDVDGAKTESTQGIVV
EEEEHHHHHHHCCCCHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEE
ILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQGL
EEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHCC
NREQRMAITAA
CHHHCEEEECC
>Mature Secondary Structure 
SMDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
ILQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYIC
HHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
NALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPRDESKLRIVLSRLKANEVDLL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHH
EEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLCFVIEADQIAFEKVVTAPVEKAQ
HHHHCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKTEVAPVASPAVVAPAAKSAAHEHHAGREKPARERESTSIRVAVEKVDQLINLVGELVI
HHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
TQSMLAQRSNELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIEMPEKRLEAGKNVVGNL
HHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHH
ILSAEHQGGNICIEVTDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAE
HEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHH
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGSGTTIRILLPLTLAILDGMSVRVAGEV
HHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEECEE
FILPLNAVMESLQPREEDLHPLAGGERVLEVRGEYLPLVELWKVFDVDGAKTESTQGIVV
EEEEHHHHHHHCCCCHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEE
ILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQGL
EEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHCC
NREQRMAITAA
CHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]