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The map label for this gene is rcsA

Identifier: 29141382

GI number: 29141382

Start: 994820

End: 995443

Strand: Reverse

Name: rcsA

Synonym: t0895

Alternate gene names: 29141382

Gene position: 995443-994820 (Counterclockwise)

Preceding gene: 29141383

Following gene: 29141380

Centisome position: 20.77

GC content: 38.62

Gene sequence:

>624_bases
ATGTCAACGATTATTATGGATTTATGCAGTTACACCCGGCTAGGGTTAAGCGGGTATCTGGTCAGCAGAGGGGTGAAAAA
AAGGGAAATCAACGACATCGAAACCGTTGACGAACTCGCTATCGCTTGTGGCGCACATCAGCCTTCGGTGGTGTTTATTA
ATGAGGACTGTTTCATTCATACGCCTTCAGACAGTCAACAAATAAAGCAAATCATTAATCAGCATCCTGACACGTTATTT
ATTGTTTTTATGGCAATTGCTAATGTGCATTTTGATGAATATTTATTAGTAAGAAAAAACTTATTGATTAGCTCTAAATC
GATTAAACCTGACTCGCTGGATACCCTTCTTGGCGATATTCTGAAAAAAGAGTCGGGTATTTCAGGAACCATAAATTTAC
CAACATTATCGTTAAGTCGAACTGAATCCAGCATGTTACGAATGTGGATGGAAGGTCAGGGAACCATTCAGATTTCTGAC
AGAATGAATATTAAAGCAAAAACAGTATCCTCCCATAAGGGGAATATAAAAAGAAAGATAAAAACGCATAATAAACAAGT
GATCTATCACGTAGTGCGGCTGACAGATAACGTCACTAACGGCATTTTTGCTAACATGCGCTGA

Upstream 100 bases:

>100_bases
CGCGTAAGCGTTGTCTAAGGTGACTATTCGTGTTCCGTCTGATTATGGTGAGTTATTCAGGTAAGGGGAATTATCGTTAC
GCATTGAGTGAGGGTATGCC

Downstream 100 bases:

>100_bases
GACATCCGGACTGGCAATGTACCTCCAGTCCGGCTCAATTAGTCCTGCTCCGCCTTCTCGACAAAAATACCATCCTGGTG
ACCTGACTCATTGAAGAACC

Product: colanic acid capsullar biosynthesis activation protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSTIIMDLCSYTRLGLSGYLVSRGVKKREINDIETVDELAIACGAHQPSVVFINEDCFIHTPSDSQQIKQIINQHPDTLF
IVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTLLGDILKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISD
RMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFANMR

Sequences:

>Translated_207_residues
MSTIIMDLCSYTRLGLSGYLVSRGVKKREINDIETVDELAIACGAHQPSVVFINEDCFIHTPSDSQQIKQIINQHPDTLF
IVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTLLGDILKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISD
RMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFANMR
>Mature_206_residues
STIIMDLCSYTRLGLSGYLVSRGVKKREINDIETVDELAIACGAHQPSVVFINEDCFIHTPSDSQQIKQIINQHPDTLFI
VFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTLLGDILKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISDR
MNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFANMR

Specific function: Positive regulator of capsular polysaccharide synthesis. RcsA and rcsB form a complex to promote transcription of the genes for capsule synthesis

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788262, Length=207, Percent_Identity=87.43961352657, Blast_Score=377, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RCSA_SALTI (Q56083)

Other databases:

- EMBL:   X87687
- EMBL:   AL627272
- EMBL:   AE014613
- RefSeq:   NP_456543.1
- RefSeq:   NP_804724.1
- ProteinModelPortal:   Q56083
- GeneID:   1070177
- GeneID:   1248530
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t0895
- KEGG:   sty:STY2190
- HOGENOM:   HBG417356
- OMA:   EDCFIHE
- ProtClustDB:   PRK15411
- BioCyc:   SENT209261:T0895-MONOMER
- BioCyc:   SENT220341:STY2190-MONOMER
- GO:   GO:0005622
- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421

Pfam domain/function: PF00196 GerE; SSF46894 Bipartite_resp_reg_C-effector

EC number: NA

Molecular weight: Translated: 23274; Mature: 23143

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIIMDLCSYTRLGLSGYLVSRGVKKREINDIETVDELAIACGAHQPSVVFINEDCFIH
CCHHHHHHHHHHHHCHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEE
TPSDSQQIKQIINQHPDTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTLLGDI
CCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
LKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISDRMNIKAKTVSSHKGNIKRKI
HHHCCCCCEEEECCEEEECHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFANMR
HHCCHHHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure 
STIIMDLCSYTRLGLSGYLVSRGVKKREINDIETVDELAIACGAHQPSVVFINEDCFIH
CHHHHHHHHHHHHCHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEE
TPSDSQQIKQIINQHPDTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPDSLDTLLGDI
CCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
LKKESGISGTINLPTLSLSRTESSMLRMWMEGQGTIQISDRMNIKAKTVSSHKGNIKRKI
HHHCCCCCEEEECCEEEECHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFANMR
HHCCHHHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626298; 11677608; 12644504