Click here to switch to the map view.

The map label for this gene is cbiA [H]

Identifier: 29141336

GI number: 29141336

Start: 933507

End: 934931

Strand: Direct

Name: cbiA [H]

Synonym: t0840

Alternate gene names: 29141336

Gene position: 933507-934931 (Clockwise)

Preceding gene: 29141335

Following gene: 29141337

Centisome position: 19.48

GC content: 55.79

Gene sequence:

>1425_bases
ATGCGCGTACCTGTATACCCCTACCACCCTGAACAGGATCAGGGTAATGGCGGCAAGGCATCACGCTTTATTCTTGCAGG
CACAGGAAGCGGTTGCGGCAAAACCACGGTGACGCTTGGTTTGTTGAGGCTGCTGCAAAAACGCGCGCTGCGCGTACAGC
CGTTTAAAGTTGGGCCAGATTACCTTGATACCGGCTGGCATACCGCTATCTGTGGCGTGGCGTCCCGTAATCTTGACAGT
TTCATGCTTCCTCCTCCTGTTCTCAACGCCTTATTTTGCGAACAAATGCGGCAGGCGGATATCGCTGTCATTGAAGGCGT
CATGGGGCTGTATGACGGCTATGGCGTCGACCCCAATTACTGCAGCACAGCCGCGATGGCCAAACAGCTTGGTTGCCCGG
TCATCCTACTGGTGGACGGCAAGGCTGTTTCAACGTCGCTTGCGGCTATCGTTATGGGATTTCAGCACTTCGACCCGACC
CTCAACCTCGCGGGCGTGATTGTGAATCGCGTCACTAGCGACGCCCACTATCAGCTCCTCAAAAATGCCATTGAACATTA
TTGCTCACTGCCGGTACTGGGGTATGTCCCTCCTTGCGACGGCGTCGCATTACCTGAACGCCACCTGGGGTTGATTACCG
CCAGAGAATCCCTCGTCAATCAGCAATCATGGCATGATTTTGCCGCCACGCTGGAACAAACAGTGGATGTGGATGCGCTA
CTCTCGCTGAGCCTGTTATCAGCGCTTCCGGCGGGAATGTGGCCTGAACGCCCCGATAACACAGCGGGGGCAGGGCTGAC
GCTTGCTCTGGCGGATGATGAGGCCTTTAACTTTTATTACCCCGATAACATCGATTTGCTGGAGCGTGCCGGCGTTAACA
TTGTGCGTTTTAGCCCACTGCATGACCGCGCATTGCCTGATTGTCAGATGATCTGGCTGGGCGGTGGATATCCTGAATTA
TACGCCGCGGATCTGGCGGCAAATACGGCGATGTTAAAACATTTGCGGGCGGCGCATCAGCGCGGCGTGGCGATTTACGC
GGAGTGTGGCGGTCTGATGTATCTGGGGAGCACTCTGGAGGATAGCGGCGGGGAAATTCATCAGATGGCGAATATTATCC
CCGGTCACAGCAAAATGGGTAAGCGACTTACCCGCTTTGGTTACTGTGAGGCGCAGGCTATGCAGCCAACGCTATTGGCG
GTGCCTGGCGAGATAGTGCGCGGCCATGAATTTCACTACTCAGATTTTATCCCCGAAACACCCGCCGTTATGGCCTGTCG
TAAGGTTCGCGATGGCCGCGTGTTACAAGAATGGACTGGCGGCTGGCAGACAGGCAACACGTTTGCCAGCTATCTGCACG
TCCATTTCGCCCAGCGTCCGGAAATGTTGCAGCACTGGCTGGCGGCGGCGAGGCGAGTATTATGA

Upstream 100 bases:

>100_bases
GGCGAGGAGGACGCTAAGCCAGAAGACCTGCCTGTCGGTGATAACCAACAACTTCGGTGGGAAGTGGGTTGCGAAGACGC
GTACAGTCGAAAGACTGAAC

Downstream 100 bases:

>100_bases
CGATCCTTGCCTGGTGTATCGCCTGGGTGCTGGATTTTATCATCGGCGACCCTCAACACTGGCCCCATCCGGTACGCTGG
ATAGGCCGATTAATTACGTT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MRVPVYPYHPEQDQGNGGKASRFILAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPDYLDTGWHTAICGVASRNLDS
FMLPPPVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNYCSTAAMAKQLGCPVILLVDGKAVSTSLAAIVMGFQHFDPT
LNLAGVIVNRVTSDAHYQLLKNAIEHYCSLPVLGYVPPCDGVALPERHLGLITARESLVNQQSWHDFAATLEQTVDVDAL
LSLSLLSALPAGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDLLERAGVNIVRFSPLHDRALPDCQMIWLGGGYPEL
YAADLAANTAMLKHLRAAHQRGVAIYAECGGLMYLGSTLEDSGGEIHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLA
VPGEIVRGHEFHYSDFIPETPAVMACRKVRDGRVLQEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRVL

Sequences:

>Translated_474_residues
MRVPVYPYHPEQDQGNGGKASRFILAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPDYLDTGWHTAICGVASRNLDS
FMLPPPVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNYCSTAAMAKQLGCPVILLVDGKAVSTSLAAIVMGFQHFDPT
LNLAGVIVNRVTSDAHYQLLKNAIEHYCSLPVLGYVPPCDGVALPERHLGLITARESLVNQQSWHDFAATLEQTVDVDAL
LSLSLLSALPAGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDLLERAGVNIVRFSPLHDRALPDCQMIWLGGGYPEL
YAADLAANTAMLKHLRAAHQRGVAIYAECGGLMYLGSTLEDSGGEIHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLA
VPGEIVRGHEFHYSDFIPETPAVMACRKVRDGRVLQEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRVL
>Mature_474_residues
MRVPVYPYHPEQDQGNGGKASRFILAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPDYLDTGWHTAICGVASRNLDS
FMLPPPVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNYCSTAAMAKQLGCPVILLVDGKAVSTSLAAIVMGFQHFDPT
LNLAGVIVNRVTSDAHYQLLKNAIEHYCSLPVLGYVPPCDGVALPERHLGLITARESLVNQQSWHDFAATLEQTVDVDAL
LSLSLLSALPAGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDLLERAGVNIVRFSPLHDRALPDCQMIWLGGGYPEL
YAADLAANTAMLKHLRAAHQRGVAIYAECGGLMYLGSTLEDSGGEIHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLA
VPGEIVRGHEFHYSDFIPETPAVMACRKVRDGRVLQEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRVL

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 51757; Mature: 51757

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVPVYPYHPEQDQGNGGKASRFILAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPD
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCEECCEECCCC
YLDTGWHTAICGVASRNLDSFMLPPPVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNY
HHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
CSTAAMAKQLGCPVILLVDGKAVSTSLAAIVMGFQHFDPTLNLAGVIVNRVTSDAHYQLL
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHH
KNAIEHYCSLPVLGYVPPCDGVALPERHLGLITARESLVNQQSWHDFAATLEQTVDVDAL
HHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LSLSLLSALPAGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDLLERAGVNIVRFSPL
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCHHHHHCCCCEEEECCC
HDRALPDCQMIWLGGGYPELYAADLAANTAMLKHLRAAHQRGVAIYAECGGLMYLGSTLE
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCC
DSGGEIHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLAVPGEIVRGHEFHYSDFIPET
CCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCEEEECCHHHHCCCCCCHHCCCCCC
PAVMACRKVRDGRVLQEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRVL
HHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVPVYPYHPEQDQGNGGKASRFILAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPD
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCEECCEECCCC
YLDTGWHTAICGVASRNLDSFMLPPPVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNY
HHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
CSTAAMAKQLGCPVILLVDGKAVSTSLAAIVMGFQHFDPTLNLAGVIVNRVTSDAHYQLL
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHH
KNAIEHYCSLPVLGYVPPCDGVALPERHLGLITARESLVNQQSWHDFAATLEQTVDVDAL
HHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LSLSLLSALPAGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDLLERAGVNIVRFSPL
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCHHHHHCCCCEEEECCC
HDRALPDCQMIWLGGGYPELYAADLAANTAMLKHLRAAHQRGVAIYAECGGLMYLGSTLE
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCC
DSGGEIHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLAVPGEIVRGHEFHYSDFIPET
CCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCEEEECCHHHHCCCCCCHHCCCCCC
PAVMACRKVRDGRVLQEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRVL
HHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 1374146 [H]