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The map label for this gene is pocR [H]

Identifier: 29141335

GI number: 29141335

Start: 932041

End: 932955

Strand: Direct

Name: pocR [H]

Synonym: t0838

Alternate gene names: 29141335

Gene position: 932041-932955 (Clockwise)

Preceding gene: 29141334

Following gene: 29141336

Centisome position: 19.45

GC content: 46.01

Gene sequence:

>915_bases
ATGATTTCTGCGAGCGCTCTGAACTCAGAACTCATTAATAAAATCGCACAGGATTTTGCACAAGCCACCACCGGTCTGGC
GGTTGTGGTTGTCAATATTCATGGTGATGAAATATCTGAGCTATTCAATTTCACGCCGTTTTGTCAGTTGATGCGGCAGC
ATCCCCAGCATAGTACACGTTGTCGTATGAGCGATCGCTGCGGGGGACTGGAGGCATCGAAGTCCGATCAACCCTGTATT
TATCGTTGTCATGCCGGTCTAACGGATTTTTCTATTCCGCTGGTAATCGCAGGGCATTTAGTTGGCTTTGTTTTATGCGG
GCAGGTTCGTTTAAGTAATGACGTGGAGCTGGTAAACATTCTTAATGTCGACGATCGCTGGCAGGCTGACCCTGAGCTCT
TGAATGAATTTCGGAATGTGCCAGAGATGGACTATTCACGCGTTATCGCTTCCGCCGATCTTCTTAAACTGATAGTTGAG
AATTGCCTGAAAAAACAGCTCAATTTCGTGGTTATCAAAGACAATCCGCAGCAATCGGAGGCAAATAAAACCACTCGTGG
CCCCACTCCGCATGACAGTAAAATGAAAAAAGCGCTTCGCTATATTGATGCGCATTTGTCCGACGATCTTCGTCTTGAGG
ATGTCGCCTCACATGTCTATCTCAGCCCCTATTACTTCAGTAAGCTATTCAAGAAATATCAGGGAATCGGATTTAATGCG
TGGGTGAACCGCCAGAGAATGGTTAGCGCCAGAGAATTGCTTTGCCATAGTGACTGGAGTATTGCCAGTATTGCGCGTAA
TTTAGGCTTTTCGCAAACCAGTTATTTTTGCAAAGTCTTCCGCCAGACCTATCAGGTTACGCCGCAGGCTTATCGTCAGC
AGATAAATGAGAATTCTCATCCTCCATCGATATAA

Upstream 100 bases:

>100_bases
TGTCATTGTACTTTTTATCAGGGCCAGGATAATGCTAATAAAAAGTGAATGTAAATAATGTGTTTTGTTTATAACAATAA
ATTAACTGAGGGGTTTTATC

Downstream 100 bases:

>100_bases
ATAGCAATATTTTGCTATTGCCGATTTTTGATAGTGTTTTGTATCTTAATCATTTCAGAAAGAAAATTTATCTGGTGTAA
CAATAAATTGTCATAGCGCA

Product: pdu/cob regulatory protein PocR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MISASALNSELINKIAQDFAQATTGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRCRMSDRCGGLEASKSDQPCI
YRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNILNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVE
NCLKKQLNFVVIKDNPQQSEANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNA
WVNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHPPSI

Sequences:

>Translated_304_residues
MISASALNSELINKIAQDFAQATTGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRCRMSDRCGGLEASKSDQPCI
YRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNILNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVE
NCLKKQLNFVVIKDNPQQSEANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNA
WVNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHPPSI
>Mature_304_residues
MISASALNSELINKIAQDFAQATTGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRCRMSDRCGGLEASKSDQPCI
YRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNILNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVE
NCLKKQLNFVVIKDNPQQSEANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNA
WVNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHPPSI

Specific function: Positive regulatory protein of pdu and cob operons [H]

COG id: COG4936

COG function: function code TK; Predicted sensor domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790391, Length=99, Percent_Identity=39.3939393939394, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786251, Length=109, Percent_Identity=35.7798165137615, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790339, Length=101, Percent_Identity=30.6930693069307, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR018771 [H]

Pfam domain/function: PF10114 Hist_Kin_Sens; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34516; Mature: 34516

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISASALNSELINKIAQDFAQATTGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTR
CCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHCCCHHHHHHHHCCCCHHH
CRMSDRCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNI
CCHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCEEEEE
LNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVENCLKKQLNFVVIKDNPQQSE
ECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHH
ANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHH
WVNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSH
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
PPSI
CCCC
>Mature Secondary Structure
MISASALNSELINKIAQDFAQATTGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTR
CCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHCCCHHHHHHHHCCCCHHH
CRMSDRCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNI
CCHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCEEEEE
LNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVENCLKKQLNFVVIKDNPQQSE
ECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHH
ANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHH
WVNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSH
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
PPSI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8071226; 9352910; 11677609; 8501034 [H]