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The map label for this gene is ugd [H]

Identifier: 29141293

GI number: 29141293

Start: 888023

End: 889189

Strand: Direct

Name: ugd [H]

Synonym: t0793

Alternate gene names: 29141293

Gene position: 888023-889189 (Clockwise)

Preceding gene: 29141292

Following gene: 29141294

Centisome position: 18.53

GC content: 43.36

Gene sequence:

>1167_bases
ATGAAAATCACGATATCCGGGACGGGTTATGTTGGCTTGTCTAATGGTTTGCTTATTGCACAACACCATGATGTGGTGGC
GTTAGACATTGTTCCTGCCCGTGTTGAACTGTTAAATGATCGGATATCTCCGATTGTTGATAAAGAAATTCAGCAATTTT
TAAAGGAAGATAACATCAGATTCAGGGCAACGCTGGATAAGTTTGATGCATACCAGAATGCAGATTACGTCATCATTGCT
ACGCCTACAGATTACGATCCAAAAACCAACTATTTTAATACGTTCAGTGTAGAATCGGTCATTCAGGATGTGATCAGCAT
CAACCCCGCAGCCGTGATGATTATTAAGTCTACGGTGCCGGTTGGCTTTACGGCGGCAATGCGTCAGAAGTTTGCGACAG
AAAATATCATTTTCTCTCCGGAATTTTTACGTGAAGGTAAAGCCCTTTACGATAACCTTTATCCCTCCCGTATCGTGATT
GGGGAACAGTCTGAGCGCGCCCGAGAATTTGCCGCATTACTCCAGGAAGGCGCTATTAAACAGGAGATTCCGACGCTGTT
TACGGACTCCACTGAAGCGGAAGCCATTAAACTTTTCGCCAATACTTACCTCGCCATGCGAGTCGCTTATTTTAATGAAT
TAGACAGTTATGCTGAAACGTTAGGATTAAATACCCGACAAATTATTGAAGGGGTGTGCCTCGACCCGCGTATTGGCAAT
CATTACAATAATCCCTCTTTTGGTTATGGCGGATATTGTTTGCCAAAAGATACCAAACAGTTGCTGGCTAATTATCAGTC
AGTGCCTAATAATATTATCTCCGCTATCGTTGAAGCAAACCGTACGCGTAAAGATTTTATTGCCGATTCTATCCTTGCCA
GAAAGCCTAAAGTGGTGGGCATTTATCGCCTGATTATGAAGAGTGGCTCCGATAACTTCCGCGCCTCATCGATTCAGGGG
ATTATGAAACGTATTAAAGCGAAAGGCGTAGAGGTCATCATCTATGAGCCGGTAATGCAAGAAGAAACTTTCTTTAACTC
ACGTCTTGAACGTGATTTGCACTGCTTTAAACAGCAGGCGGATGTCATTATTTCCAATCGGATGGCGGCAGAGCTTTTGG
ATGTCGCTGAAAAAGTGTATACCCGCGATCTTTTCGGTAGTGATTAA

Upstream 100 bases:

>100_bases
CTGCGTTGCACTTTATATACTCAGGCGTTAAAACTTTGATATCTTATCAGGATGCGAAATACATCATGATTCATAATTAA
GTTAATTCTGAGAGCGAATA

Downstream 100 bases:

>100_bases
TAAGGCAATCGGGGCTGATGAGTCCCGATGATTTATTGACCAAATGGAAATAATGTCTGATTTTTATCATTAATCCTATG
GCATATATTTTCTTTATGAC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKITISGTGYVGLSNGLLIAQHHDVVALDIVPARVELLNDRISPIVDKEIQQFLKEDNIRFRATLDKFDAYQNADYVIIA
TPTDYDPKTNYFNTFSVESVIQDVISINPAAVMIIKSTVPVGFTAAMRQKFATENIIFSPEFLREGKALYDNLYPSRIVI
GEQSERAREFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNIISAIVEANRTRKDFIADSILARKPKVVGIYRLIMKSGSDNFRASSIQG
IMKRIKAKGVEVIIYEPVMQEETFFNSRLERDLHCFKQQADVIISNRMAAELLDVAEKVYTRDLFGSD

Sequences:

>Translated_388_residues
MKITISGTGYVGLSNGLLIAQHHDVVALDIVPARVELLNDRISPIVDKEIQQFLKEDNIRFRATLDKFDAYQNADYVIIA
TPTDYDPKTNYFNTFSVESVIQDVISINPAAVMIIKSTVPVGFTAAMRQKFATENIIFSPEFLREGKALYDNLYPSRIVI
GEQSERAREFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNIISAIVEANRTRKDFIADSILARKPKVVGIYRLIMKSGSDNFRASSIQG
IMKRIKAKGVEVIIYEPVMQEETFFNSRLERDLHCFKQQADVIISNRMAAELLDVAEKVYTRDLFGSD
>Mature_388_residues
MKITISGTGYVGLSNGLLIAQHHDVVALDIVPARVELLNDRISPIVDKEIQQFLKEDNIRFRATLDKFDAYQNADYVIIA
TPTDYDPKTNYFNTFSVESVIQDVISINPAAVMIIKSTVPVGFTAAMRQKFATENIIFSPEFLREGKALYDNLYPSRIVI
GEQSERAREFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNIISAIVEANRTRKDFIADSILARKPKVVGIYRLIMKSGSDNFRASSIQG
IMKRIKAKGVEVIIYEPVMQEETFFNSRLERDLHCFKQQADVIISNRMAAELLDVAEKVYTRDLFGSD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=372, Percent_Identity=27.6881720430108, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI296040438, Length=247, Percent_Identity=28.7449392712551, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI296040443, Length=221, Percent_Identity=28.5067873303167, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=88.1443298969072, Blast_Score=709, Evalue=0.0,
Organism=Escherichia coli, GI48994968, Length=376, Percent_Identity=25, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560350, Length=383, Percent_Identity=25.8485639686684, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17136908, Length=376, Percent_Identity=25.531914893617, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43690; Mature: 43690

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITISGTGYVGLSNGLLIAQHHDVVALDIVPARVELLNDRISPIVDKEIQQFLKEDNIR
CEEEEECCCEEECCCCEEEEECCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCE
FRATLDKFDAYQNADYVIIATPTDYDPKTNYFNTFSVESVIQDVISINPAAVMIIKSTVP
EEEEHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCC
VGFTAAMRQKFATENIIFSPEFLREGKALYDNLYPSRIVIGEQSERAREFAALLQEGAIK
CCHHHHHHHHHHHCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCHH
QEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTRQIIEGVCLDPRIGN
HHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNIISAIVEANRTRKDFIADSILARKPKVVG
CCCCCCCCCCCEECCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
IYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMQEETFFNSRLERDLHCFKQQA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
DVIISNRMAAELLDVAEKVYTRDLFGSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKITISGTGYVGLSNGLLIAQHHDVVALDIVPARVELLNDRISPIVDKEIQQFLKEDNIR
CEEEEECCCEEECCCCEEEEECCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCE
FRATLDKFDAYQNADYVIIATPTDYDPKTNYFNTFSVESVIQDVISINPAAVMIIKSTVP
EEEEHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCC
VGFTAAMRQKFATENIIFSPEFLREGKALYDNLYPSRIVIGEQSERAREFAALLQEGAIK
CCHHHHHHHHHHHCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCHH
QEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTRQIIEGVCLDPRIGN
HHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNIISAIVEANRTRKDFIADSILARKPKVVG
CCCCCCCCCCCEECCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
IYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMQEETFFNSRLERDLHCFKQQA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
DVIISNRMAAELLDVAEKVYTRDLFGSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7682279; 11677609 [H]