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The map label for this gene is eco [H]

Identifier: 29141116

GI number: 29141116

Start: 687209

End: 687703

Strand: Reverse

Name: eco [H]

Synonym: t0602

Alternate gene names: 29141116

Gene position: 687703-687209 (Counterclockwise)

Preceding gene: 29141132

Following gene: 29141110

Centisome position: 14.35

GC content: 54.55

Gene sequence:

>495_bases
ATGAAGATGTTTGTCCCTGCCGTCGTCTTCGCCGCCCTCGCCAGCGCCTCTGCCTGGGCTAACAATGGCGATACCGCCCA
GCCGCTGGAAAAAATCGCCCCCTATCCGCAGGCGGAGAAAGGAATGAAGCGGCAAGTGATAACCCTTACCCCTCAGCAGG
ATGAATCTACCCTCAAAGTGGAACTGTTGATTGGTCAAACGCTGAATGTGGATTGTAACCAGCATCGCCTCGGCGGCACG
CTGGAAACAAAAACGCTGGAAGGCTGGGGCTACGACTATTATGTCTTTGATAACGTCACCTCTCCGGTATCAACCATGAT
GGCCTGCCCTGAAGGTAAGAAAGAGCAAAAATTCGTCACCGCCTGGCTGGGTGAAGACGGGATGCTGCGCTACAACAGCA
AGCTGCCGATCGTGGTGTATACCCCGGCGAATGTGGACGTGAAATACCGCATCTGGAAAGCGGACGCTAACGTACAGAAT
GCCATCGCGCGATAA

Upstream 100 bases:

>100_bases
GAAAATATGAGTAAATACAGATTAATAGATAATATGAATGTGTTAATCTGTTGTCTGTGCATACCGAAAACAGCAGAAAG
GAAATACTGTGAACAATCAA

Downstream 100 bases:

>100_bases
TGTTACGCTGCCCGGTCACACTTACCGGGCATCTGAACACGCCGACTCACGCAGCGCTCCGGGGTTCTTTTTAAAACACG
TCTGGAAACCCGCTCGCCCG

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKVELLIGQTLNVDCNQHRLGGT
LETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQN
AIAR

Sequences:

>Translated_164_residues
MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKVELLIGQTLNVDCNQHRLGGT
LETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQN
AIAR
>Mature_164_residues
MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKVELLIGQTLNVDCNQHRLGGT
LETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQN
AIAR

Specific function: General inhibitor of pancreatic serine proteases:inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=164, Percent_Identity=78.6585365853659, Blast_Score=275, Evalue=7e-76,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 18232; Mature: 18232

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEE
ELLIGQTLNVDCNQHRLGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVT
EEEECCEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHCCCCCCCCCEEEE
AWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQNAIAR
EEECCCCEEEECCCCCEEEECCCCCEEEEEEEECCCCHHHHHCC
>Mature Secondary Structure
MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEE
ELLIGQTLNVDCNQHRLGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVT
EEEECCEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHCCCCCCCCCEEEE
AWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQNAIAR
EEECCCCEEEECCCCCEEEECCCCCEEEEEEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA