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The map label for this gene is sseL [H]

Identifier: 29141091

GI number: 29141091

Start: 651344

End: 652297

Strand: Reverse

Name: sseL [H]

Synonym: t0576

Alternate gene names: 29141091

Gene position: 652297-651344 (Counterclockwise)

Preceding gene: 29141092

Following gene: 29141083

Centisome position: 13.61

GC content: 37.95

Gene sequence:

>954_bases
GTGAGCGATGAGGCGCTTGCGTTGTTGTTTAGCGCCGTAGAGAACGGTGATCAGAATTGTATTGATCTGTTATGCAATCT
TGCGTTACGCAATGATAACCTGGGACATAGAGTTGAGAAATTTCTTTTTGATCTCTTTAGCGGAAAAAGATCGGGATCAC
CAGACATAGACAAAAAAATCAATCAGGCTTGCCTTGTATTACATCAAATCGCCAATAACGATATAACAAAAGATAATACT
GAGTGGAAAAAGCTACATGCCCCTTCCAGATTACTTTATATGGCCGGTTCCGCGACAACCGACCTTTCTAAAAAAATAGG
AATAGCACATAAAATTATGGGCGACCAGTTCGCTCAGACAGATCAAGAACAGGTAGGAGTTGAAAATCTTTGGTGTAGTG
CGCGAATGTTGTCGTCAGATGAGCTAGCAGCCGCAACGCTAGGTCTGGTTCAAGAATCACCTCTTCTCTCGGTAAACTAT
CCTATTGGGCTTATTCATCCTACCACCAAAGAAAATATATTACGCACTCAGCTACTTGAAAAGATGGCTCAATCAGGATT
ATCTGAAAATGAAGTCTTTCTGATAAATACAGGAGATCACTGGCTTATCTGTTTATTTTATAAACTTGCAGAAAAAATAA
AATGCCTTATATTTAATACTTATCATGATTTAAATGAAAATACTAAGCAAGAGATTATAGAAGCAGCAAAAATTGCAGGC
ATATCAGAAAACGAAGATATTGATTTTATTGAAACCAATTTACAAAATAATGTACCCAACGGCTGTGGTCTATTTTGTTA
CCATACAATTCAACTCTTATCGAATGCAGGACAAAACGATCCTGCTACCACACTACGAGAATTTGCGGAAAATTTCTTAA
CGCTTTCAGTAGAGGAACAAACACTATTTAACACCCAAACCCGGCGACAAATATATGAATACAGTCTCCAGTAA

Upstream 100 bases:

>100_bases
GTTACTTTCACCTACCAGGAAACAGAGCAAAATGAATATATGTGTAAATTCACTTTACCGATTGAGCACACCGCAATTTC
ACAGTTTATATTCAGAAGAG

Downstream 100 bases:

>100_bases
TGGCGAGTACTTATCCTGAAATGATGCTCTGCCAAGAATTTATAAGTATATAAGGATGGGAAGGCCAAGCCTTCCCACTA
AAAGTTCTATGCCGTCAATG

Product: deubiquitinase

Products: NA

Alternate protein names: Deubiquitinating enzyme; DUB; Deubiquitinating protease; Salmonella secreted effector L [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSDEALALLFSAVENGDQNCIDLLCNLALRNDNLGHRVEKFLFDLFSGKRSGSPDIDKKINQACLVLHQIANNDITKDNT
EWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQTDQEQVGVENLWCSARMLSSDELAAATLGLVQESPLLSVNY
PIGLIHPTTKENILRTQLLEKMAQSGLSENEVFLINTGDHWLICLFYKLAEKIKCLIFNTYHDLNENTKQEIIEAAKIAG
ISENEDIDFIETNLQNNVPNGCGLFCYHTIQLLSNAGQNDPATTLREFAENFLTLSVEEQTLFNTQTRRQIYEYSLQ

Sequences:

>Translated_317_residues
MSDEALALLFSAVENGDQNCIDLLCNLALRNDNLGHRVEKFLFDLFSGKRSGSPDIDKKINQACLVLHQIANNDITKDNT
EWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQTDQEQVGVENLWCSARMLSSDELAAATLGLVQESPLLSVNY
PIGLIHPTTKENILRTQLLEKMAQSGLSENEVFLINTGDHWLICLFYKLAEKIKCLIFNTYHDLNENTKQEIIEAAKIAG
ISENEDIDFIETNLQNNVPNGCGLFCYHTIQLLSNAGQNDPATTLREFAENFLTLSVEEQTLFNTQTRRQIYEYSLQ
>Mature_316_residues
SDEALALLFSAVENGDQNCIDLLCNLALRNDNLGHRVEKFLFDLFSGKRSGSPDIDKKINQACLVLHQIANNDITKDNTE
WKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQTDQEQVGVENLWCSARMLSSDELAAATLGLVQESPLLSVNYP
IGLIHPTTKENILRTQLLEKMAQSGLSENEVFLINTGDHWLICLFYKLAEKIKCLIFNTYHDLNENTKQEIIEAAKIAGI
SENEDIDFIETNLQNNVPNGCGLFCYHTIQLLSNAGQNDPATTLREFAENFLTLSVEEQTLFNTQTRRQIYEYSLQ

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cytoplasm (By similarity). Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm. In phagocytic cells localizes to the Salmonella-containing vacuole (SCV). In epithelial cells localizes to the Sal

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C79 family [H]

Homologues:

Organism=Escherichia coli, GI1788604, Length=341, Percent_Identity=28.7390029325513, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35603; Mature: 35472

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDEALALLFSAVENGDQNCIDLLCNLALRNDNLGHRVEKFLFDLFSGKRSGSPDIDKKI
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
NQACLVLHQIANNDITKDNTEWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQT
HHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
DQEQVGVENLWCSARMLSSDELAAATLGLVQESPLLSVNYPIGLIHPTTKENILRTQLLE
CHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCEEEECCCCHHHHHHHHHHH
KMAQSGLSENEVFLINTGDHWLICLFYKLAEKIKCLIFNTYHDLNENTKQEIIEAAKIAG
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
ISENEDIDFIETNLQNNVPNGCGLFCYHTIQLLSNAGQNDPATTLREFAENFLTLSVEEQ
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEECHH
TLFNTQTRRQIYEYSLQ
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDEALALLFSAVENGDQNCIDLLCNLALRNDNLGHRVEKFLFDLFSGKRSGSPDIDKKI
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
NQACLVLHQIANNDITKDNTEWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQT
HHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
DQEQVGVENLWCSARMLSSDELAAATLGLVQESPLLSVNYPIGLIHPTTKENILRTQLLE
CHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCEEEECCCCHHHHHHHHHHH
KMAQSGLSENEVFLINTGDHWLICLFYKLAEKIKCLIFNTYHDLNENTKQEIIEAAKIAG
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
ISENEDIDFIETNLQNNVPNGCGLFCYHTIQLLSNAGQNDPATTLREFAENFLTLSVEEQ
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEECHH
TLFNTQTRRQIYEYSLQ
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA