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The map label for this gene is pgtP [H]

Identifier: 29140980

GI number: 29140980

Start: 531254

End: 532645

Strand: Reverse

Name: pgtP [H]

Synonym: t0459

Alternate gene names: 29140980

Gene position: 532645-531254 (Counterclockwise)

Preceding gene: 29140985

Following gene: 29140978

Centisome position: 11.12

GC content: 49.86

Gene sequence:

>1392_bases
ATGTTAACAATATTAAAAACAGGGCGATCGGCGCATAAAGTCCCACCGGAAAAAGTCCAGGCTACGTATGGTCGATATCG
TATACAGGCATTGTTAAGCGTATTTCTGGGATATCTCGCTTACTATATAGTCAGAAACAACTTCACATTATCGACGCCTT
ATTTAAAAGAGCAATTGGATCTCAGCGCTACGCAAATCGGCCTGCTGAGTAGCTGTATGCTTATTGCTTACGGAATCAGT
AAAGGCGTAATGAGCAGTCTGGCGGATAAAGCCAGCCCAAAAGTCTTCATGGCGTGCGGTCTGGTACTCTGCGTGATTGT
TAACGTTGGGCTGGGATTCAGTAGCGCATTCTGGATATTTGCCGCTCTGGTGGTCTTCAATGGCCTTTTTCAGGGCATGG
GCGTCGGCCCCTCGTTTATTACTATTGCAAACTGGTTCCCTCGTCGGGAACGCGGACGCGTAGGCGCCTTCTGGAATATC
TCGCATAACGTTGGCGGCGGGATCGTCGCGCCTATCGTCGGTGCGGCTTTTGCGATATTGGGCAGCGAACACTGGCAAAG
CGCCAGTTATATCGTTCCGGCCTGCGTCGCCGTCATTTTTGCCTTAATTGTTCTGGTCTTGGGAAAAGGTTCGCCGCGCG
AAGAAGGTCTTCCCTCCCTGGAACAGATGATGCCGGAAGAAAAAGTCATACTGAAAACGAAGAATACGGCAAAAGCGCCG
GAAAATATGAGCGCATGGCAAATCTTCTGTACTTATGTGCTGCGCAATAAAAATGCCTGGTATATTTCGCTGGTCGATGT
CTTCGTCTATATGGTGCGGTTTGGCATGATTAGCTGGTTGCCTATCTATCTGTTGACAGTAAAACACTTTTCAAAAGAAC
AGATGAGCGTCGCGTTTCTCTTTTTCGAGTGGGCGGCAATTCCCTCTACGCTACTGGCAGGCTGGCTGTCAGATAAACTG
TTTAAGGGCCGCAGAATGCCGTTAGCCATGATTTGCATGGCGCTGATTTTTGTCTGTCTGATCGGATACTGGAAAAGTGA
ATCTTTGCTGATGGTAACGATTTTCGCCGCCATTGTAGGTTGTCTGATTTACGTCCCGCAATTCCTCGCGTCCGTACAGA
CAATGGAGATAGTCCCCAGCTTTGCCGTAGGTTCCGCCGTCGGTTTACGTGGGTTCATGAGCTATATTTTCGGCGCCTCG
TTGGGCACCAGCCTGTTTGGCGTCATGGTGGATAAACTGGGCTGGTACGGCGGATTTTATCTTCTGATGGGCGGCATCGT
GTGCTGCATTCTATTCTGTTACCTCTCCCATCGCGGCGCGCTGGAACTGGAACGCCAGCGCCAGAATGCGTTACATAATC
AGGACTCACTGCAGCTTGCGGACGCGCAATAA

Upstream 100 bases:

>100_bases
ATTTTGACACATTTCCTCGACTTGAATTTTATTGTCACTCCTTTCACTCTACCGACAAAACCTCCTGATGTTCATCTCAC
TATAAAATACAGGTGACTCC

Downstream 100 bases:

>100_bases
ACGATTAGCCTTCCCGGGGAACAGAAGCGCCGACATTGTCGGCGCTATCTATTCGCTGACATCGTGTATACCAAAAATAA
TTCGAGTTGCTTAAAAGCGG

Product: phosphoglycerate transporter protein

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MLTILKTGRSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCVIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ

Sequences:

>Translated_463_residues
MLTILKTGRSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCVIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ
>Mature_463_residues
MLTILKTGRSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCVIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=412, Percent_Identity=26.4563106796117, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4503847, Length=412, Percent_Identity=26.4563106796117, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI256219483, Length=412, Percent_Identity=26.4563106796117, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI256219543, Length=434, Percent_Identity=25.5760368663594, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI38093649, Length=406, Percent_Identity=24.384236453202, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI223717983, Length=406, Percent_Identity=24.384236453202, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1788573, Length=462, Percent_Identity=36.1471861471861, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI2367259, Length=470, Percent_Identity=32.5531914893617, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87082310, Length=448, Percent_Identity=30.5803571428571, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI2367379, Length=328, Percent_Identity=25.3048780487805, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI2367193, Length=448, Percent_Identity=22.0982142857143, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082320, Length=398, Percent_Identity=22.3618090452261, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17564202, Length=403, Percent_Identity=22.0843672456576, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=403, Percent_Identity=22.0843672456576, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=445, Percent_Identity=20.6741573033708, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI133901854, Length=443, Percent_Identity=22.5733634311512, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133901856, Length=443, Percent_Identity=22.5733634311512, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51070; Mature: 51070

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTILKTGRSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLD
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHC
LSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCVIVNVGLGFSSAFWIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
AALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAIL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
GSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
CCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCC
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFL
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FFEWAAIPSTLLAGWLSDKLFKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKLGWYGGFY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEECCCC
>Mature Secondary Structure
MLTILKTGRSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLD
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHC
LSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCVIVNVGLGFSSAFWIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
AALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAIL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
GSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLPSLEQMMPEEKVILKTKNTAKAP
CCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCC
ENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFL
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FFEWAAIPSTLLAGWLSDKLFKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKLGWYGGFY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]