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The map label for this gene is yfeR [H]

Identifier: 29140960

GI number: 29140960

Start: 506407

End: 507333

Strand: Direct

Name: yfeR [H]

Synonym: t0433

Alternate gene names: 29140960

Gene position: 506407-507333 (Clockwise)

Preceding gene: 29140958

Following gene: 29140962

Centisome position: 10.57

GC content: 56.74

Gene sequence:

>927_bases
ATGAACTATTCACTGCGTCAACTGCGGATTTTTATTACCGTCGCCCAGGCCAAAAGTTTTAGTCGGGCAGGGGACAGGAT
TGGACTGAGCCAGTCTGCGGTCAGTCATAGCGTAAAAGAGCTGGAGCGGCAAACCGGCGTCAGACTGTTGGATCGCACCA
CGCGTGAGGTGGTGCTGACCGAGGCGGGGCAACAGCTGGCGACGCGTCTGGAGCGGGTGCTTGATGAACTGAACAGCATA
CTGCGCGATGCAGGCAGAGTAGGGACACAATTAACCGGCACCGTGCGCGTTGCCGCGAGCCAAACCATTTCTGCGCATCT
TATTCCGCAATGCATTGCCCAAAGTAATTCACTTTATCCCGCTATTGATTTTGTATTGCACGATCGTCCGCAGCAGTGGG
TGCTGGAGAGCATCCGCCAGGGTGAAGTGGATTTTGGCATCGTTATCGATCCCGGCGCAGCGGTGGATTTACAGTGTGAA
GCCATCTTATCAGAGCCTTTTTTACTGTTGTGTCGCCAGGATCATCCGCTGGCGCATCAGGAATGGGTGAGCTGGCAGGA
TCTTAAACAGGCCTCGCTGGTCTTACAGGATTATGCTTCCGGCAGTCGACCGCTGATTGATGCGGCGCTGGCCCATTTTG
CTATTGAGGCGGATATCGTGCAGGAGATTGGTCACCCGGCCACGCTGTTTCCAATGGTGGAAGCGGGAATCGGCATCAGC
GTGCTGCCCGCGCTGGCGTTACCGCTCCCGCAGGGCAGCCACTTACAGGTTAAACGGCTGACGCCCGTAGTTGAAAGGCA
GCTCATGCTGGCGCGGCGAAAAAACCGATCGCTCTCCACGGCGGCGCAGGCGTTGTGGGACGTGGTGCGTACTCAGGCCA
GCGAATTAACCGCCGCGAGGGCGAAAGATCCGCTGTATCAGCTATAA

Upstream 100 bases:

>100_bases
AAAAGTTTCATAAAAACTCCTGAAAGTCGGTGCAGCTATTTTGCGTTTTTCGCTTTGAGAAATAAAATTGATTTATTGCA
TCTATATATGAATCTAGTCG

Downstream 100 bases:

>100_bases
ATATCTATCTGTCCGTGTGTGAGGTGCGGTCTTGCCCTGCCATTTTTGACAGGGCAGTGTGTTAAAACAGGTATTTGATG
GAATAAATAATGCCATCCTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNYSLRQLRIFITVAQAKSFSRAGDRIGLSQSAVSHSVKELERQTGVRLLDRTTREVVLTEAGQQLATRLERVLDELNSI
LRDAGRVGTQLTGTVRVAASQTISAHLIPQCIAQSNSLYPAIDFVLHDRPQQWVLESIRQGEVDFGIVIDPGAAVDLQCE
AILSEPFLLLCRQDHPLAHQEWVSWQDLKQASLVLQDYASGSRPLIDAALAHFAIEADIVQEIGHPATLFPMVEAGIGIS
VLPALALPLPQGSHLQVKRLTPVVERQLMLARRKNRSLSTAAQALWDVVRTQASELTAARAKDPLYQL

Sequences:

>Translated_308_residues
MNYSLRQLRIFITVAQAKSFSRAGDRIGLSQSAVSHSVKELERQTGVRLLDRTTREVVLTEAGQQLATRLERVLDELNSI
LRDAGRVGTQLTGTVRVAASQTISAHLIPQCIAQSNSLYPAIDFVLHDRPQQWVLESIRQGEVDFGIVIDPGAAVDLQCE
AILSEPFLLLCRQDHPLAHQEWVSWQDLKQASLVLQDYASGSRPLIDAALAHFAIEADIVQEIGHPATLFPMVEAGIGIS
VLPALALPLPQGSHLQVKRLTPVVERQLMLARRKNRSLSTAAQALWDVVRTQASELTAARAKDPLYQL
>Mature_308_residues
MNYSLRQLRIFITVAQAKSFSRAGDRIGLSQSAVSHSVKELERQTGVRLLDRTTREVVLTEAGQQLATRLERVLDELNSI
LRDAGRVGTQLTGTVRVAASQTISAHLIPQCIAQSNSLYPAIDFVLHDRPQQWVLESIRQGEVDFGIVIDPGAAVDLQCE
AILSEPFLLLCRQDHPLAHQEWVSWQDLKQASLVLQDYASGSRPLIDAALAHFAIEADIVQEIGHPATLFPMVEAGIGIS
VLPALALPLPQGSHLQVKRLTPVVERQLMLARRKNRSLSTAAQALWDVVRTQASELTAARAKDPLYQL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=308, Percent_Identity=79.2207792207792, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=32.404181184669, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=28.7625418060201, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI157672245, Length=280, Percent_Identity=28.9285714285714, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=30.4, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788481, Length=292, Percent_Identity=28.0821917808219, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=28.9795918367347, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI87081904, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787128, Length=211, Percent_Identity=32.7014218009479, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=26.6393442622951, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787601, Length=174, Percent_Identity=28.735632183908, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367136, Length=242, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786401, Length=126, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787530, Length=249, Percent_Identity=22.4899598393574, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788296, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693193, Length=125, Percent_Identity=35.2, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787589, Length=116, Percent_Identity=33.6206896551724, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=167, Percent_Identity=28.7425149700599, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786713, Length=177, Percent_Identity=29.3785310734463, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788706, Length=177, Percent_Identity=24.8587570621469, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788626, Length=250, Percent_Identity=26.8, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789506, Length=296, Percent_Identity=22.6351351351351, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789204, Length=284, Percent_Identity=24.6478873239437, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=246, Percent_Identity=22.3577235772358, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=28.6885245901639, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790208, Length=300, Percent_Identity=23.3333333333333, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33949; Mature: 33949

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSLRQLRIFITVAQAKSFSRAGDRIGLSQSAVSHSVKELERQTGVRLLDRTTREVVLT
CCCCCEEHEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EAGQQLATRLERVLDELNSILRDAGRVGTQLTGTVRVAASQTISAHLIPQCIAQSNSLYP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCH
AIDFVLHDRPQQWVLESIRQGEVDFGIVIDPGAAVDLQCEAILSEPFLLLCRQDHPLAHQ
HHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHCCCCEEEECCCCCCCHH
EWVSWQDLKQASLVLQDYASGSRPLIDAALAHFAIEADIVQEIGHPATLFPMVEAGIGIS
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHH
VLPALALPLPQGSHLQVKRLTPVVERQLMLARRKNRSLSTAAQALWDVVRTQASELTAAR
HHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AKDPLYQL
HCCCCCCC
>Mature Secondary Structure
MNYSLRQLRIFITVAQAKSFSRAGDRIGLSQSAVSHSVKELERQTGVRLLDRTTREVVLT
CCCCCEEHEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EAGQQLATRLERVLDELNSILRDAGRVGTQLTGTVRVAASQTISAHLIPQCIAQSNSLYP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCH
AIDFVLHDRPQQWVLESIRQGEVDFGIVIDPGAAVDLQCEAILSEPFLLLCRQDHPLAHQ
HHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHCCCCEEEECCCCCCCHH
EWVSWQDLKQASLVLQDYASGSRPLIDAALAHFAIEADIVQEIGHPATLFPMVEAGIGIS
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHH
VLPALALPLPQGSHLQVKRLTPVVERQLMLARRKNRSLSTAAQALWDVVRTQASELTAAR
HHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AKDPLYQL
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]