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The map label for this gene is murQ [H]

Identifier: 29140820

GI number: 29140820

Start: 323290

End: 324183

Strand: Direct

Name: murQ [H]

Synonym: t0286

Alternate gene names: 29140820

Gene position: 323290-324183 (Clockwise)

Preceding gene: 29140818

Following gene: 29140821

Centisome position: 6.75

GC content: 57.27

Gene sequence:

>894_bases
ATGAATCTTGGTACCTTAGTGTCTGAAACCCGTAACCCGCAAACGATGGATCTGGATGCGTTGTCTACTCCTGAATTAGT
TAAGCGTTTTAATGAACAGGATACGCTGGTAGCGGAAGCAGTAAAAGCCACTCTGCCTGACGTTGCGCGTGCGGTGGATG
CTGCTGCGGCGGCGCTGAAGTCTGGCGGACGTATCATCTATATGGGGGCGGGCACCAGTGGTCGGCTTGGCGTACTGGAT
GCCTCAGAATGCCCCCCGACGTTTGGCGTTCCGCACGGTCTGGTCGTCGGGCTGATTGCCGGCGGGCCGGGCGCGTTGCT
GAAGGCGGTCGAAGGCGCGGAAGACAGCCAACAGGCAGGCGAAGACGATCTTGTCGCGCTAAATCTGCAAGAACAGGATC
TGGTCGTGGGGCTCGCGGCGTCGGGTCGTACACCCTATGTGATTGGTGGCCTGCGCTATGCGCGACAGTCCGGTTGTACC
ACTGTTGCCGTCTCCTGTAATCCAGATTCGCCTATTGCGCGGGAGGCTAATATCGCTATTTCGCCCGTTGTCGGGCCGGA
AGCGCTTACCGGCTCCACGCGGCTGAAATCCGGCACCGCGCAGAAAATGGTGCTCAATATGATTTCTACCGGCGCGATGG
TGAAGTTCGGTAAGGTCTATCAGAACCTGATGGTGGATATGAAAGCCACCAACGTCAAACTGGTCGATCGCGCGTGTCGG
ATGGTCGTTGAAGCGACCGGGATAGGTCGTGAAGAGGCGGAAACGTTGCTGAAACAGACCGATTTTGAGGTTAAGCCCGC
CATTTTGATGGCGCTTACGGGGCTGGATGCTGCAGCCGCCAGGGAAAAACTCGCCGCTCATCAGGGCTTTTTAAGGGCGG
CGTTAGAACACTAA

Upstream 100 bases:

>100_bases
AACGTGATGGCGACGACAAAACGAAATTTCACTCGCCTGGGGGAATATTCTATTCCATCATGGACGCTTATTATGAATTA
AAAATTCCAGAGGGACAAAA

Downstream 100 bases:

>100_bases
AGAGGTGTGTATGGATAAGACGGCAGCGCTCGCCAGCGACATTTTACGTGGTATCGGCGGAGAGCAAAATATTCTGCGCC
TGGAAAACTGTATGACGCGA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNLGTLVSETRNPQTMDLDALSTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLD
ASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCT
TVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACR
MVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH

Sequences:

>Translated_297_residues
MNLGTLVSETRNPQTMDLDALSTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLD
ASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCT
TVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACR
MVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
>Mature_297_residues
MNLGTLVSETRNPQTMDLDALSTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLD
ASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCT
TVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACR
MVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=296, Percent_Identity=54.7297297297297, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30895; Mature: 30895

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLGTLVSETRNPQTMDLDALSTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALK
CCCCCHHHCCCCCCEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAG
CCCEEEEEECCCCCCEEEEECCCCCCCCCCCCHHEEEEECCCHHHHHHHHCCCCCHHHCC
EDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAI
CCCEEEEEECCCCEEEEEECCCCCCEEECCHHHHHHCCCEEEEEEECCCCCCCCCCCEEE
SPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACR
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
HHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLGTLVSETRNPQTMDLDALSTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALK
CCCCCHHHCCCCCCEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAG
CCCEEEEEECCCCCCEEEEECCCCCCCCCCCCHHEEEEECCCHHHHHHHHCCCCCHHHCC
EDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAI
CCCEEEEEECCCCEEEEEECCCCCCEEECCHHHHHHCCCEEEEEEECCCCCCCCCCCEEE
SPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACR
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
HHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA