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The map label for this gene is ung [H]

Identifier: 29140798

GI number: 29140798

Start: 301952

End: 302641

Strand: Reverse

Name: ung [H]

Synonym: t0263

Alternate gene names: 29140798

Gene position: 302641-301952 (Counterclockwise)

Preceding gene: 29140800

Following gene: 29140796

Centisome position: 6.32

GC content: 55.36

Gene sequence:

>690_bases
ATGGCGACTGAGTTAACCTGGCACGATGTGCTGGCTGATGAGAAACAGCAACCTTACTTTATCAATACGCTTCACACTGT
TGCTGGCGAGCGTCAGTCGGGTATCACGGTCTACCCGCCGCAAAAAGATGTATTTAACGCCTTTCGCTTCACGGAACTGG
GCGACGTTAAGGTGGTGATCCTGGGACAAGATCCTTACCACGGCCCCGGCCAGGCACATGGTCTGGCGTTTTCCGTGCGT
CCTGGGATCGCTCCCCCGCCGTCATTAGTGAATATGTACAAAGAGCTGGAAGCCTCCATTCCCGGCTTTGTTCGCCCCGC
GCACGGTTATCTGGAAAGCTGGGCGCGCCAGGGCGTACTGTTACTGAATACGGTGCTCACGGTACGGGCAGGCCAGGCGC
ACTCTCATGCCAGCCTGGGGTGGGAAACCTTTACGGATAAAGTGATAAGCCTGATTAACCAACACCGCGAAGGGGTCGTC
TTCCTGCTGTGGGGCTCGCACGCCCAGAAGAAAGGCGCGATTATTGATCCACAGCGCCACCATATTCTGAAAGCTCCGCA
TCCCTCGCCACTCTCTGCGCACCGCGGATTTTTTGGCTGTAACCATTTTGCGCTAACGAACCAATGGCTGGAACAACACG
GCGAGAAAACTATCGACTGGACGCCAGTATTACCGGCTGAGAGTGAATAA

Upstream 100 bases:

>100_bases
AACTATCTTTTGTAGGTAACCGTTTTTGTAGCACGCAGGATTTTGCACTGCAGAAAGAAGCAGTTAAGCTAAGGGAACTG
GAAATTCGCAGGAGAGCGAG

Downstream 100 bases:

>100_bases
CGTTGGCGACTCGCCGTTTTATCGCCCGGATAACGGCGCGAAAGCGCCTTGTCTGACCGGGCGGTAGAAAGTACATCATT
GGCCCGGCGCGCGTTGCGTC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVR
PGIAPPPSLVNMYKELEASIPGFVRPAHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
FLLWGSHAQKKGAIIDPQRHHILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTIDWTPVLPAESE

Sequences:

>Translated_229_residues
MATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVR
PGIAPPPSLVNMYKELEASIPGFVRPAHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
FLLWGSHAQKKGAIIDPQRHHILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTIDWTPVLPAESE
>Mature_228_residues
ATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRP
GIAPPPSLVNMYKELEASIPGFVRPAHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVF
LLWGSHAQKKGAIIDPQRHHILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTIDWTPVLPAESE

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=215, Percent_Identity=59.5348837209302, Blast_Score=261, Evalue=2e-70,
Organism=Homo sapiens, GI6224979, Length=215, Percent_Identity=59.5348837209302, Blast_Score=261, Evalue=4e-70,
Organism=Escherichia coli, GI1788934, Length=229, Percent_Identity=90.8296943231441, Blast_Score=436, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17556304, Length=221, Percent_Identity=47.5113122171946, Blast_Score=217, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6323620, Length=239, Percent_Identity=49.7907949790795, Blast_Score=210, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 25480; Mature: 25349

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDVFNAFRFTELGDVKVVI
CCCCCCHHHHHCCCCCCCEEHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCEEEEE
LGQDPYHGPGQAHGLAFSVRPGIAPPPSLVNMYKELEASIPGFVRPAHGYLESWARQGVL
ECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEE
LLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDPQRH
EEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCHHH
HILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTIDWTPVLPAESE
CEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDVFNAFRFTELGDVKVVI
CCCCCHHHHHCCCCCCCEEHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCEEEEE
LGQDPYHGPGQAHGLAFSVRPGIAPPPSLVNMYKELEASIPGFVRPAHGYLESWARQGVL
ECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEE
LLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDPQRH
EEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCHHH
HILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTIDWTPVLPAESE
CEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA