Definition Tropheryma whipplei TW08/27, complete genome.
Accession NC_004551
Length 925,938

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The map label for this gene is 28572930

Identifier: 28572930

GI number: 28572930

Start: 894276

End: 895928

Strand: Direct

Name: 28572930

Synonym: TW789

Alternate gene names: NA

Gene position: 894276-895928 (Clockwise)

Preceding gene: 28572929

Following gene: 28572941

Centisome position: 96.58

GC content: 47.13

Gene sequence:

>1653_bases
TTGTCAGATATATCCACACCCATGCCGCACAACAACCGCTATGAGCTTGTAAAGTGCCTGAGGGTTGCCCGGTACTACAA
AATGTATCAAGGTTACGATAGGCGACTTAAGAGAAACGTAAATGTGGTCCTGTTTGACACTGAGGTGTCTGATAAAAAGG
AATTTTCCTTGGCTCTGGATACTAGGGTGCGTCAGGCTGTAAAACTTGACAGTCCCCATATCGCAACCATCTTTGATGGC
GGGGAAGATTATTTTTCCGATTCTATAAGACAATTTATCGCGAGCGAATCGACCCATCACGAAGAAAAATCCCTTGAGGG
GTGTTTCATTACCATCAGTAAAAGCATAAGACTCATAGCCGAAGTAATAGACGGGGTTGCACTTGCTTTGGAAGCGGGGC
GACAGGGCAATTTACCCCATGGCAGTATAAGTCCACAAAATATTACGTGTCATGATGGGTCTCTGAAAGTTATCAATTTT
GCGATTGCAACTTCTGTCAATGATGCAGCTCTTCCGCTGGAAGATGGTAAGGCATTTTTTGCACCCGAGTTACTGGTTGA
CAGATCTCTGAATGCCTATAAAGCAGAACCAAGACAGATCACATATAGAAGTGATGTGTACTCTCTGGGCGGACTGTTGT
ACTGGTTGCTTACAGGAACAACTTATATTACGGGCGAACAAGTGTGCACCACACGGTATAGGTCAGACACAAATGAGGCA
ATAGATTGTGTTTTGCGAAAGGCGCTTGCAATAGAGCCTACGAGTCGATTCTCGAGTGCAGTCGAGATGAGTGATGCCTT
ACGTAAGGCGATAGAACCTAAGAAGAAAATTGACCCTCTCAGTATAAAGGACGAGATCCTTGCGCAGGTTAATCTGCCCC
ACAAGTCAAGCCATCCGAAGCGTAAGCATAGCAATGCGGTTGCGTTTATCGCTCTTGCAATATGTGCTGTTGCTGCAGTC
ATTACCGTAAGTGCAGCGCTAATTACAACAAATCTGCCTGATAACAAACAGGCGCAGGTCGGTGCACCGTTAAGCAACTT
GTCAATGCCAAACCTTATAGGAATAGACAAGGAGCAGGCAATAAAGAAATTGAATGATCTGGGGGTAAAATTCAGAATAA
ACACAGAGCATTCTGCGACAATGCCAGTCGGCTATGTTACAGGGACATCCCCCAAGTCAGGAGCGGTTGTAGACAGTGAT
ACCGAAGTCTCAATTAGCCTATCTGACGGAATGCTTGAGCTGCCAAATTTTGTGGGTGCCAGATTTGAAGCGGCACGTCG
AGGACTTGCTGAACTGCGTCTCGAGGTAAAGAAGATCTGCTCTGGGGATACCGTAAACGCGCAAAAGCCCGCAGGCGGAT
CGATTGTGCCACAGGAAATTGAGATTACGCTGGAGACCTGTTCGGGGGCAAGTACTTCAAACACCACTGCAAGCACAGCG
CCGCGTGCAACATCACGCCCAAGCAGATCTTCCTCGAGTGCAACATCGTCGAGCTCAGTAGAAAAACTGCCTACCGAGAC
GAGTAACAGTCAAAATACTCGCACAACCCCTAGCGACAAAGAACAAGACATGAGCCGAGAAAGCTCAAATCCTTCAGGGG
CGCCCGAGCGATCAAACAGTGGCACAAACACTTCGCCAGCATCAACAAACTAA

Upstream 100 bases:

>100_bases
CCCGGAAAAAATCAAACATTCAATTCCGGGTTTTCTGACGTCCTGAAAATAAGTACGAACGGCTCACATACGCCAAGTAT
CGCATCTTCCGGATAGCGCT

Downstream 100 bases:

>100_bases
TATCGCGCGCCTTGTAGTTGTTTTTCCTGCTCTGATAAGGTAGAGTCAGGATTTACTCGGGTTATTCGATTGGAGTTGTG
TATATGTCAGGGTATGAAAA

Product: serine/threonine-protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MSDISTPMPHNNRYELVKCLRVARYYKMYQGYDRRLKRNVNVVLFDTEVSDKKEFSLALDTRVRQAVKLDSPHIATIFDG
GEDYFSDSIRQFIASESTHHEEKSLEGCFITISKSIRLIAEVIDGVALALEAGRQGNLPHGSISPQNITCHDGSLKVINF
AIATSVNDAALPLEDGKAFFAPELLVDRSLNAYKAEPRQITYRSDVYSLGGLLYWLLTGTTYITGEQVCTTRYRSDTNEA
IDCVLRKALAIEPTSRFSSAVEMSDALRKAIEPKKKIDPLSIKDEILAQVNLPHKSSHPKRKHSNAVAFIALAICAVAAV
ITVSAALITTNLPDNKQAQVGAPLSNLSMPNLIGIDKEQAIKKLNDLGVKFRINTEHSATMPVGYVTGTSPKSGAVVDSD
TEVSISLSDGMLELPNFVGARFEAARRGLAELRLEVKKICSGDTVNAQKPAGGSIVPQEIEITLETCSGASTSNTTASTA
PRATSRPSRSSSSATSSSSVEKLPTETSNSQNTRTTPSDKEQDMSRESSNPSGAPERSNSGTNTSPASTN

Sequences:

>Translated_550_residues
MSDISTPMPHNNRYELVKCLRVARYYKMYQGYDRRLKRNVNVVLFDTEVSDKKEFSLALDTRVRQAVKLDSPHIATIFDG
GEDYFSDSIRQFIASESTHHEEKSLEGCFITISKSIRLIAEVIDGVALALEAGRQGNLPHGSISPQNITCHDGSLKVINF
AIATSVNDAALPLEDGKAFFAPELLVDRSLNAYKAEPRQITYRSDVYSLGGLLYWLLTGTTYITGEQVCTTRYRSDTNEA
IDCVLRKALAIEPTSRFSSAVEMSDALRKAIEPKKKIDPLSIKDEILAQVNLPHKSSHPKRKHSNAVAFIALAICAVAAV
ITVSAALITTNLPDNKQAQVGAPLSNLSMPNLIGIDKEQAIKKLNDLGVKFRINTEHSATMPVGYVTGTSPKSGAVVDSD
TEVSISLSDGMLELPNFVGARFEAARRGLAELRLEVKKICSGDTVNAQKPAGGSIVPQEIEITLETCSGASTSNTTASTA
PRATSRPSRSSSSATSSSSVEKLPTETSNSQNTRTTPSDKEQDMSRESSNPSGAPERSNSGTNTSPASTN
>Mature_549_residues
SDISTPMPHNNRYELVKCLRVARYYKMYQGYDRRLKRNVNVVLFDTEVSDKKEFSLALDTRVRQAVKLDSPHIATIFDGG
EDYFSDSIRQFIASESTHHEEKSLEGCFITISKSIRLIAEVIDGVALALEAGRQGNLPHGSISPQNITCHDGSLKVINFA
IATSVNDAALPLEDGKAFFAPELLVDRSLNAYKAEPRQITYRSDVYSLGGLLYWLLTGTTYITGEQVCTTRYRSDTNEAI
DCVLRKALAIEPTSRFSSAVEMSDALRKAIEPKKKIDPLSIKDEILAQVNLPHKSSHPKRKHSNAVAFIALAICAVAAVI
TVSAALITTNLPDNKQAQVGAPLSNLSMPNLIGIDKEQAIKKLNDLGVKFRINTEHSATMPVGYVTGTSPKSGAVVDSDT
EVSISLSDGMLELPNFVGARFEAARRGLAELRLEVKKICSGDTVNAQKPAGGSIVPQEIEITLETCSGASTSNTTASTAP
RATSRPSRSSSSATSSSSVEKLPTETSNSQNTRTTPSDKEQDMSRESSNPSGAPERSNSGTNTSPASTN

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR005543
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 59507; Mature: 59375

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDISTPMPHNNRYELVKCLRVARYYKMYQGYDRRLKRNVNVVLFDTEVSDKKEFSLALD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
TRVRQAVKLDSPHIATIFDGGEDYFSDSIRQFIASESTHHEEKSLEGCFITISKSIRLIA
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEHHHHHHHH
EVIDGVALALEAGRQGNLPHGSISPQNITCHDGSLKVINFAIATSVNDAALPLEDGKAFF
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCCCCCCEEE
APELLVDRSLNAYKAEPRQITYRSDVYSLGGLLYWLLTGTTYITGEQVCTTRYRSDTNEA
CCHHHHHCCCCHHCCCCCEEEEHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHCCCCHHH
IDCVLRKALAIEPTSRFSSAVEMSDALRKAIEPKKKIDPLSIKDEILAQVNLPHKSSHPK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHCCCCCCCCCCC
RKHSNAVAFIALAICAVAAVITVSAALITTNLPDNKQAQVGAPLSNLSMPNLIGIDKEQA
HHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHCCCCCEECCCHHHH
IKKLNDLGVKFRINTEHSATMPVGYVTGTSPKSGAVVDSDTEVSISLSDGMLELPNFVGA
HHHHHHCCEEEEECCCCCCCCCEEEEECCCCCCCCEECCCCEEEEEECCCCHHHHHHHHH
RFEAARRGLAELRLEVKKICSGDTVNAQKPAGGSIVPQEIEITLETCSGASTSNTTASTA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
PRATSRPSRSSSSATSSSSVEKLPTETSNSQNTRTTPSDKEQDMSRESSNPSGAPERSNS
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
GTNTSPASTN
CCCCCCCCCC
>Mature Secondary Structure 
SDISTPMPHNNRYELVKCLRVARYYKMYQGYDRRLKRNVNVVLFDTEVSDKKEFSLALD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
TRVRQAVKLDSPHIATIFDGGEDYFSDSIRQFIASESTHHEEKSLEGCFITISKSIRLIA
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEHHHHHHHH
EVIDGVALALEAGRQGNLPHGSISPQNITCHDGSLKVINFAIATSVNDAALPLEDGKAFF
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCCCCCCEEE
APELLVDRSLNAYKAEPRQITYRSDVYSLGGLLYWLLTGTTYITGEQVCTTRYRSDTNEA
CCHHHHHCCCCHHCCCCCEEEEHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHCCCCHHH
IDCVLRKALAIEPTSRFSSAVEMSDALRKAIEPKKKIDPLSIKDEILAQVNLPHKSSHPK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHCCCCCCCCCCC
RKHSNAVAFIALAICAVAAVITVSAALITTNLPDNKQAQVGAPLSNLSMPNLIGIDKEQA
HHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHCCCCCEECCCHHHH
IKKLNDLGVKFRINTEHSATMPVGYVTGTSPKSGAVVDSDTEVSISLSDGMLELPNFVGA
HHHHHHCCEEEEECCCCCCCCCEEEEECCCCCCCCEECCCCEEEEEECCCCHHHHHHHHH
RFEAARRGLAELRLEVKKICSGDTVNAQKPAGGSIVPQEIEITLETCSGASTSNTTASTA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
PRATSRPSRSSSSATSSSSVEKLPTETSNSQNTRTTPSDKEQDMSRESSNPSGAPERSNS
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
GTNTSPASTN
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]