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The map label for this gene is murA [H]

Identifier: 28572413

GI number: 28572413

Start: 283980

End: 285305

Strand: Direct

Name: murA [H]

Synonym: TW254

Alternate gene names: 28572413

Gene position: 283980-285305 (Clockwise)

Preceding gene: 28572412

Following gene: 28572414

Centisome position: 30.67

GC content: 47.29

Gene sequence:

>1326_bases
ATGAAGCTTGATAGCACCCCTGACAGGTTTGTTATAACGGGCGGCTCGCCGTTACGTGGTGAAATTGCTGTTAAGGGTGC
TAAAAACCTTGTAACGAAGGCAATGGTCGCCTCAATGCTCGGCAATTCACAGAGCGTCTTGACAAATGTGCCCAATATAT
CGGATGTCCTTATTGTCCGGAGACTTATGGAGGCTTATAACGTAAGTGTACGTGCCACGCAGAACGACACACTCGTTATT
GATCCGATTCTTCTTGGACAGTGCTCTCGGGGTGATATTGATGTTTATGCCGGATCCAGCAGAGTTCCAATCTTGTTTTG
CGGTCCGCTACTTCATAAAACAGGACAGGCATTTATTACTGGCTTGGGCGGTTGCAGGATTGGGGAACGACCAATTGATT
TTCATTTACAAGCCCTGAGGAAGTTTGGCGCAAGTCATGAAAAACTTCCAGGTGGAATACTTCTTTCAACAAAAAAAAGA
TTGAAAGGTGCGAGTGTACACTTTCCGTATCCAAGTGTTGGTGCCACGGAACAGGTTCTGCTGACGGCTGTTTTAGCAGA
TGGTGTTACAGAGCTTAGAGGTGCCGCAATTGAGCCGGAAATAATGGATCTGATCGCGATATTGCAGAAAATGGGTGCGA
TCATTACCTGCGCACGAGACAGGGTAATTTTTATAGAGGGTGTCGACAGTTTATCAGGCTATACACACCACGCTATCAGT
GACCGCAATGAAGCCGCCAGTTGGGCCTGTGCTGCACTTGCAACGCGAGGTGATATCTTCGTGCGGAACGCCGAACAGGC
ACATCTTCTCGCATTTCTTAGTGTATACAGGAAGGTTGGTGGAGTGTTTGAGATCAAAGATGATGGAATAAGGTTTTTTC
ATCCCGGTGGTAACCTGAATCCCGTTGTTGTTGAAACAGATGTTCATCCGGGCTTCTCAACAGACTGGCAGCAGCCCCTC
GTTGTTGCCCTGACACAGGCGAGCGGCAGATCCGTCGTGCACGAGACTGTCTATGAATCTCGCTTTGGATTCACTGAAGC
TCTCAACAGAATGGGTGCAGATATTTCTGTGCACGAGAATGGTTTTCAGGGAACACTTCGCAGGGTGCCACACAGAGCCA
TAGAGCAAGCTGCTGTGATAAATGGCCCAACTCCATTGACCGGGCAAGACATAGATGTTCCAGATCTGAGAGGTGGATTC
AGTCATTTTATTGCTGCATTTGCTGCAGAAGGAAAGAGCATCATAACCAATGCGGGTATTATAAGTCGAGGGTATGAGAA
CTTTGTCCATAAGCTTGAAAGATTGAAAGTTGATTTTGAGGCATGA

Upstream 100 bases:

>100_bases
TTGCGCTTAGTCTTATAAAAACGAAAAAACCTAAGAAACTCAATAGCGTTCCCTAGCGTCTATTGACCTCTAGGGAACAC
GATGTGTTAGTTGAGATGAC

Downstream 100 bases:

>100_bases
AGGAAACGCGTTTGCCTTCGCGCTTTTGGGTTTTTACGTTTCTTATCAATCCCCTTGTGCGGCTCTTGTTTCGTTACACA
CTGCGGGGTAATGTTCCGCT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKLDSTPDRFVITGGSPLRGEIAVKGAKNLVTKAMVASMLGNSQSVLTNVPNISDVLIVRRLMEAYNVSVRATQNDTLVI
DPILLGQCSRGDIDVYAGSSRVPILFCGPLLHKTGQAFITGLGGCRIGERPIDFHLQALRKFGASHEKLPGGILLSTKKR
LKGASVHFPYPSVGATEQVLLTAVLADGVTELRGAAIEPEIMDLIAILQKMGAIITCARDRVIFIEGVDSLSGYTHHAIS
DRNEAASWACAALATRGDIFVRNAEQAHLLAFLSVYRKVGGVFEIKDDGIRFFHPGGNLNPVVVETDVHPGFSTDWQQPL
VVALTQASGRSVVHETVYESRFGFTEALNRMGADISVHENGFQGTLRRVPHRAIEQAAVINGPTPLTGQDIDVPDLRGGF
SHFIAAFAAEGKSIITNAGIISRGYENFVHKLERLKVDFEA

Sequences:

>Translated_441_residues
MKLDSTPDRFVITGGSPLRGEIAVKGAKNLVTKAMVASMLGNSQSVLTNVPNISDVLIVRRLMEAYNVSVRATQNDTLVI
DPILLGQCSRGDIDVYAGSSRVPILFCGPLLHKTGQAFITGLGGCRIGERPIDFHLQALRKFGASHEKLPGGILLSTKKR
LKGASVHFPYPSVGATEQVLLTAVLADGVTELRGAAIEPEIMDLIAILQKMGAIITCARDRVIFIEGVDSLSGYTHHAIS
DRNEAASWACAALATRGDIFVRNAEQAHLLAFLSVYRKVGGVFEIKDDGIRFFHPGGNLNPVVVETDVHPGFSTDWQQPL
VVALTQASGRSVVHETVYESRFGFTEALNRMGADISVHENGFQGTLRRVPHRAIEQAAVINGPTPLTGQDIDVPDLRGGF
SHFIAAFAAEGKSIITNAGIISRGYENFVHKLERLKVDFEA
>Mature_441_residues
MKLDSTPDRFVITGGSPLRGEIAVKGAKNLVTKAMVASMLGNSQSVLTNVPNISDVLIVRRLMEAYNVSVRATQNDTLVI
DPILLGQCSRGDIDVYAGSSRVPILFCGPLLHKTGQAFITGLGGCRIGERPIDFHLQALRKFGASHEKLPGGILLSTKKR
LKGASVHFPYPSVGATEQVLLTAVLADGVTELRGAAIEPEIMDLIAILQKMGAIITCARDRVIFIEGVDSLSGYTHHAIS
DRNEAASWACAALATRGDIFVRNAEQAHLLAFLSVYRKVGGVFEIKDDGIRFFHPGGNLNPVVVETDVHPGFSTDWQQPL
VVALTQASGRSVVHETVYESRFGFTEALNRMGADISVHENGFQGTLRRVPHRAIEQAAVINGPTPLTGQDIDVPDLRGGF
SHFIAAFAAEGKSIITNAGIISRGYENFVHKLERLKVDFEA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=440, Percent_Identity=32.9545454545455, Blast_Score=205, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47583; Mature: 47583

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDSTPDRFVITGGSPLRGEIAVKGAKNLVTKAMVASMLGNSQSVLTNVPNISDVLIVR
CCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHH
RLMEAYNVSVRATQNDTLVIDPILLGQCSRGDIDVYAGSSRVPILFCGPLLHKTGQAFIT
HHHHHHCCEEEEECCCEEEECHHHCCCCCCCCEEEEECCCCCCEEEECHHHHHCCCEEEE
GLGGCRIGERPIDFHLQALRKFGASHEKLPGGILLSTKKRLKGASVHFPYPSVGATEQVL
ECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECHHHCCCCEEECCCCCCCCHHHHH
LTAVLADGVTELRGAAIEPEIMDLIAILQKMGAIITCARDRVIFIEGVDSLSGYTHHAIS
HHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEECCCHHCCCCHHHHC
DRNEAASWACAALATRGDIFVRNAEQAHLLAFLSVYRKVGGVFEIKDDGIRFFHPGGNLN
CCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCCC
PVVVETDVHPGFSTDWQQPLVVALTQASGRSVVHETVYESRFGFTEALNRMGADISVHEN
CEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEECC
GFQGTLRRVPHRAIEQAAVINGPTPLTGQDIDVPDLRGGFSHFIAAFAAEGKSIITNAGI
CCHHHHHHCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCH
ISRGYENFVHKLERLKVDFEA
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLDSTPDRFVITGGSPLRGEIAVKGAKNLVTKAMVASMLGNSQSVLTNVPNISDVLIVR
CCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHH
RLMEAYNVSVRATQNDTLVIDPILLGQCSRGDIDVYAGSSRVPILFCGPLLHKTGQAFIT
HHHHHHCCEEEEECCCEEEECHHHCCCCCCCCEEEEECCCCCCEEEECHHHHHCCCEEEE
GLGGCRIGERPIDFHLQALRKFGASHEKLPGGILLSTKKRLKGASVHFPYPSVGATEQVL
ECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECHHHCCCCEEECCCCCCCCHHHHH
LTAVLADGVTELRGAAIEPEIMDLIAILQKMGAIITCARDRVIFIEGVDSLSGYTHHAIS
HHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEECCCHHCCCCHHHHC
DRNEAASWACAALATRGDIFVRNAEQAHLLAFLSVYRKVGGVFEIKDDGIRFFHPGGNLN
CCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCCC
PVVVETDVHPGFSTDWQQPLVVALTQASGRSVVHETVYESRFGFTEALNRMGADISVHEN
CEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEECC
GFQGTLRRVPHRAIEQAAVINGPTPLTGQDIDVPDLRGGFSHFIAAFAAEGKSIITNAGI
CCHHHHHHCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCH
ISRGYENFVHKLERLKVDFEA
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA