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The map label for this gene is ykuT [H]

Identifier: 28378856

GI number: 28378856

Start: 2043435

End: 2044328

Strand: Direct

Name: ykuT [H]

Synonym: lp_2262

Alternate gene names: 28378856

Gene position: 2043435-2044328 (Clockwise)

Preceding gene: 28378852

Following gene: 28378863

Centisome position: 61.77

GC content: 44.85

Gene sequence:

>894_bases
ATGTTTAATTCAATTAACCTAGCAGCGGTTGACACACCGACTAAACAAGTTTCGGTGTGGATGAAGTTGGCTAAGAAAAT
TGACTGGCAACAAATTATTATTAATATTGGCGGCAAGCTACTCGAAATCATTTTATTTATTTTACTATTTTGGGTGATTG
ATCGGCTAGGAAAACGCCTGATCCACCACTTATTTTTAACGAATGCTAATACCAGTGATACTGCCAATAATCGGATTTCA
ACGATTTTTACATTATCATTAAATATCTACCATTACGTCATCATGTTTTTTGGCATCTATGCGGTACTTTCAGTGTTAGG
TGTTCCCGTGGGGACGTTGATTGCTAGTGCTGGGATTTTCAGTGTGGCGTTAGGTTTAGGCGCCCAAGGCTTCGTCAGTG
ACATTGTCACCGGGTTCTTCATTCTACTTGAAGATCAGATTGATGTTGGGGATTACGTCAAAATCGAAACCATTGAGGGG
ACCGTCTCCGCAATCGGTTTACGGACAACTCAAGTTACGAGTCCCGATGGCACGTTGAACTTTATTCCCAATCGCAAGAT
TTTAATCATTAGCAACCAGTCGCGTAACGATATGCGCGTGCTGATTGACCTCTACATTCTCACAACGACTCCCGTTCAAG
ATCTGACTAACGTGGTCCGCGAAACTAATGCCGACCTCGTGCCTCAGTATCCTGATATCATCGGTGAGCCCGACATTCAA
GGCGTCACGACACAAGCCGATGGGACGTTGGTCTTCCGAGTACAATTTTACGTCAAAAATGGCATGCAGTTCGCAATTCA
GCGCGACTTTTTGGCCGCCTACTTGAACGCGGCCCGAGCAGCGGGAATTCAACTCCCCTCGCCACGTTTAAATATCGCCC
CAACGCACAAGTAA

Upstream 100 bases:

>100_bases
TCACCCAGTCACATTTGGTCGCAATAACTTGATCACGGCTTGGTTGCCCGCGTCAAATCTGATAAACTAGTGAACAGACA
ACAATAACGAGGGTGAAGAT

Downstream 100 bases:

>100_bases
GCTCAACCAACACAAGCCCGCACAGCGGTTGCTCAGAAATGAGCGCCACGGTGCGGGCTTGATCTTTCATCTGACAAATT
TCTTCAGGTGGGAACCATGA

Product: mechanosensitive transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MFNSINLAAVDTPTKQVSVWMKLAKKIDWQQIIINIGGKLLEIILFILLFWVIDRLGKRLIHHLFLTNANTSDTANNRIS
TIFTLSLNIYHYVIMFFGIYAVLSVLGVPVGTLIASAGIFSVALGLGAQGFVSDIVTGFFILLEDQIDVGDYVKIETIEG
TVSAIGLRTTQVTSPDGTLNFIPNRKILIISNQSRNDMRVLIDLYILTTTPVQDLTNVVRETNADLVPQYPDIIGEPDIQ
GVTTQADGTLVFRVQFYVKNGMQFAIQRDFLAAYLNAARAAGIQLPSPRLNIAPTHK

Sequences:

>Translated_297_residues
MFNSINLAAVDTPTKQVSVWMKLAKKIDWQQIIINIGGKLLEIILFILLFWVIDRLGKRLIHHLFLTNANTSDTANNRIS
TIFTLSLNIYHYVIMFFGIYAVLSVLGVPVGTLIASAGIFSVALGLGAQGFVSDIVTGFFILLEDQIDVGDYVKIETIEG
TVSAIGLRTTQVTSPDGTLNFIPNRKILIISNQSRNDMRVLIDLYILTTTPVQDLTNVVRETNADLVPQYPDIIGEPDIQ
GVTTQADGTLVFRVQFYVKNGMQFAIQRDFLAAYLNAARAAGIQLPSPRLNIAPTHK
>Mature_297_residues
MFNSINLAAVDTPTKQVSVWMKLAKKIDWQQIIINIGGKLLEIILFILLFWVIDRLGKRLIHHLFLTNANTSDTANNRIS
TIFTLSLNIYHYVIMFFGIYAVLSVLGVPVGTLIASAGIFSVALGLGAQGFVSDIVTGFFILLEDQIDVGDYVKIETIEG
TVSAIGLRTTQVTSPDGTLNFIPNRKILIISNQSRNDMRVLIDLYILTTTPVQDLTNVVRETNADLVPQYPDIIGEPDIQ
GVTTQADGTLVFRVQFYVKNGMQFAIQRDFLAAYLNAARAAGIQLPSPRLNIAPTHK

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786670, Length=204, Percent_Identity=29.9019607843137, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081787, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 32825; Mature: 32825

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNSINLAAVDTPTKQVSVWMKLAKKIDWQQIIINIGGKLLEIILFILLFWVIDRLGKRL
CCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IHHLFLTNANTSDTANNRISTIFTLSLNIYHYVIMFFGIYAVLSVLGVPVGTLIASAGIF
HHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SVALGLGAQGFVSDIVTGFFILLEDQIDVGDYVKIETIEGTVSAIGLRTTQVTSPDGTLN
HHHHHCCCHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCHHHEEEEEEEEECCCCCEE
FIPNRKILIISNQSRNDMRVLIDLYILTTTPVQDLTNVVRETNADLVPQYPDIIGEPDIQ
ECCCCEEEEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCHHCCCCCCC
GVTTQADGTLVFRVQFYVKNGMQFAIQRDFLAAYLNAARAAGIQLPSPRLNIAPTHK
CEEECCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFNSINLAAVDTPTKQVSVWMKLAKKIDWQQIIINIGGKLLEIILFILLFWVIDRLGKRL
CCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IHHLFLTNANTSDTANNRISTIFTLSLNIYHYVIMFFGIYAVLSVLGVPVGTLIASAGIF
HHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SVALGLGAQGFVSDIVTGFFILLEDQIDVGDYVKIETIEGTVSAIGLRTTQVTSPDGTLN
HHHHHCCCHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCHHHEEEEEEEEECCCCCEE
FIPNRKILIISNQSRNDMRVLIDLYILTTTPVQDLTNVVRETNADLVPQYPDIIGEPDIQ
ECCCCEEEEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCHHCCCCCCC
GVTTQADGTLVFRVQFYVKNGMQFAIQRDFLAAYLNAARAAGIQLPSPRLNIAPTHK
CEEECCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]