Click here to switch to the map view.

The map label for this gene is paiA [H]

Identifier: 28378488

GI number: 28378488

Start: 1647364

End: 1647891

Strand: Direct

Name: paiA [H]

Synonym: lp_1820

Alternate gene names: 28378488

Gene position: 1647364-1647891 (Clockwise)

Preceding gene: 28378487

Following gene: 28378489

Centisome position: 49.8

GC content: 43.75

Gene sequence:

>528_bases
ATGTCACAAATTACGACACGGCGGCTCACCACTGCTGACGTGAACAAACTACAACAAATCAGTATTGAAACCTTTAAGGA
CACGTTTGGTGCACAAAACTCCTCTGAAAATATGGCCGCATACTTACAAGATGCATATAACTTGCCCAAGTTAACCCATG
AATTAGCGGAACCCGAATCACAATTTTATTTTGTTGAACGAGCCGGTGAATCATTAGGATACTTGAAATTAAACACCGGT
GCGGCACAATCAGAAGCAATGGGTCCAGACACTTTAGAAGTCGAACGAATCTATATCCGAAAAGCTTTCCAACACCAAGG
GCTCGGTAATCAATTTATGCAACAAGCGATTCAAATTGCTAAAGCTGATCATAAGCAGAAGATCTGGCTTGGTGTTTGGG
AGCATAACGAACCCGCGAAGGGCTTCTATGCGAAGTGGGGCTTTGAACAATTCAGTGCTCACGATTTTGTGATGGGGGAC
GATCGCCAAACCGATTTGCTCATGATCAAGTCACTGACCCAAGACTAA

Upstream 100 bases:

>100_bases
AATATGTTAAGATAAAGCAGTCAGTCACATCATTAGCGCATTTACAGCGTTGATTGTGTGACCGACTGTTTTTGCTAGGA
AACTATAGGAGGAATTGATC

Downstream 100 bases:

>100_bases
GGGCAGTAAAGGCTTTTGAGTGAACTGCTTTTACAAGTTTAGAATTAGTCGCTGTCTGTGGCGACCAGCAGATTACAAAT
TTATTTACCCCTTGTTTTTT

Product: transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSQITTRRLTTADVNKLQQISIETFKDTFGAQNSSENMAAYLQDAYNLPKLTHELAEPESQFYFVERAGESLGYLKLNTG
AAQSEAMGPDTLEVERIYIRKAFQHQGLGNQFMQQAIQIAKADHKQKIWLGVWEHNEPAKGFYAKWGFEQFSAHDFVMGD
DRQTDLLMIKSLTQD

Sequences:

>Translated_175_residues
MSQITTRRLTTADVNKLQQISIETFKDTFGAQNSSENMAAYLQDAYNLPKLTHELAEPESQFYFVERAGESLGYLKLNTG
AAQSEAMGPDTLEVERIYIRKAFQHQGLGNQFMQQAIQIAKADHKQKIWLGVWEHNEPAKGFYAKWGFEQFSAHDFVMGD
DRQTDLLMIKSLTQD
>Mature_174_residues
SQITTRRLTTADVNKLQQISIETFKDTFGAQNSSENMAAYLQDAYNLPKLTHELAEPESQFYFVERAGESLGYLKLNTGA
AQSEAMGPDTLEVERIYIRKAFQHQGLGNQFMQQAIQIAKADHKQKIWLGVWEHNEPAKGFYAKWGFEQFSAHDFVMGDD
RQTDLLMIKSLTQD

Specific function: Possesses N1-acetyltransferase activity toward polyamine substrates including spermidine and spermine. Can acetylate both spermidine and spermine. In this way it may function in regulating intracellular polyamine concentrations and/or binding capabilities

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 19986; Mature: 19854

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQITTRRLTTADVNKLQQISIETFKDTFGAQNSSENMAAYLQDAYNLPKLTHELAEPES
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCH
QFYFVERAGESLGYLKLNTGAAQSEAMGPDTLEVERIYIRKAFQHQGLGNQFMQQAIQIA
HEEEEECCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KADHKQKIWLGVWEHNEPAKGFYAKWGFEQFSAHDFVMGDDRQTDLLMIKSLTQD
HCCCCCEEEEEEECCCCCCCCHHHHCCCHHHCCCCEEECCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SQITTRRLTTADVNKLQQISIETFKDTFGAQNSSENMAAYLQDAYNLPKLTHELAEPES
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCH
QFYFVERAGESLGYLKLNTGAAQSEAMGPDTLEVERIYIRKAFQHQGLGNQFMQQAIQIA
HEEEEECCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KADHKQKIWLGVWEHNEPAKGFYAKWGFEQFSAHDFVMGDDRQTDLLMIKSLTQD
HCCCCCEEEEEEECCCCCCCCHHHHCCCHHHCCCCEEECCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108124; 9384377 [H]