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The map label for this gene is glmM

Identifier: 28377670

GI number: 28377670

Start: 759740

End: 761095

Strand: Direct

Name: glmM

Synonym: lp_0820

Alternate gene names: 28377670

Gene position: 759740-761095 (Clockwise)

Preceding gene: 28377669

Following gene: 28377671

Centisome position: 22.96

GC content: 46.53

Gene sequence:

>1356_bases
ATGAAATATTTTGGTACTGATGGTGTTCGGGGAATTGCAAATTCAGGCTTAACACCTGAAATGGCTTTTCGTTTAGGTCG
TGCTGGTGGCTACGTATTGACGGAACATGCGGAAAACAAGAGTACGCAACCACGCGTTTTAGTTGCACGCGATACCCGGA
TTTCGGGCCAAATGCTGGAAGAAGCCTTGATTGCCGGCTTGCTTTCAGCCGGAATTGAAGTTTTACGTCTCGGTGTAATT
ACGACGCCAGGAGTGGCCTACTTAGTACGGATCCAAGATGCTGACGCGGGTGTCATGATCTCGGCTTCTCACAATCCAGT
TGAAGATAACGGGATCAAGTTCTTCGGTGGCGACGGCTTCAAGTTGTCTGATGCCAAGGAAGAAGAAATCGAAGAATTAC
TGGATCAACCGAAAGACACTTTACCACGGCCAGCAGCAGAAGGTCTGGGGACAGTTGCTGATTTTCCAGAGGGTAATCTT
AAATATTCACAATTCTTGGAACAAACGATTCCAGATGACTTAAGTGGCATTCATTTGGCTGTCGATGGTGCCAATGGTTC
TACCAGTAACTTAGTTTCCCGGATCTTTGCGGATTTGAACGTGGAATTTGATACGATGGCTACGGCACCAGATGGCTTGA
ACATCAACAAAGGGGTCGGTTCAACACATCCCGAAGCATTATCTAAATTCGTCGTTGAAAAAGGCGCTCAAGTTGGTTTA
GCCTTTGATGGGGACGGTGATCGTTGTATCGCAGTCGATGAACTTGGAAACATTATTGACGGTGACAAGATTATGTACAT
CTGTGGAAAATTCCTCAGTGAACGAGGCAAGTTGAAGCAGGATACAGTCGTCACAACGGTCATGAGTAACCTGGGCTTAT
ACAAGGCCTTAGAAGCAGCTGGTTTGCACAGCAAGCAGACCCAAGTTGGTGACCGCTACGTTGTCGAAGAGATGTTGAAG
GACGGCTATAACCTTGGTGGTGAACAATCTGGTCACGTGGTCTTCTTAGACTTTAATACGACGGGTGATGGCATGTTGAC
TGGAATTCAGTTATTGCACGTCATGAAGGAAACGGGTAAGAAGCTTTCTGAATTAGCCGCCGAAGTGACGACTTACCCAC
AAAAGTTAGTGAATGTTAAGGTTCAAGACAAGAAAGCCGCTTTGAACAATGATAAGATCAAGGCAGTTATCAAGGACGTT
GAAGATGAAATGGCCGGTGATGGTCGCGTCTTGGTACGGCCTTCTGGAACCCAAGATTTATTGCGGGTCATGGCAGAAGC
GAAGACCGACGAACTGGTTAGCGCTTATGTAGATCGGATCGTCGATGTGGTCAAAGCTGAAGTTGGCATTGAATAA

Upstream 100 bases:

>100_bases
GATGAGGATGGGATCTCGTCAGTTAGCCCGACGTCGGTCAAAGTAAAAATTACAGTTAAAAATGATTAATCATGACACTT
TTGAAATGAGGTAAATTATA

Downstream 100 bases:

>100_bases
TTAAGTGATCAGACCGATCATCAAAAAAGTCGTTACTCTTAGAGTTGCGACTTTTTTGTTGCCATGAAACGCACGGTCAT
TGCTAAATGCGGTTGGCGCG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKYFGTDGVRGIANSGLTPEMAFRLGRAGGYVLTEHAENKSTQPRVLVARDTRISGQMLEEALIAGLLSAGIEVLRLGVI
TTPGVAYLVRIQDADAGVMISASHNPVEDNGIKFFGGDGFKLSDAKEEEIEELLDQPKDTLPRPAAEGLGTVADFPEGNL
KYSQFLEQTIPDDLSGIHLAVDGANGSTSNLVSRIFADLNVEFDTMATAPDGLNINKGVGSTHPEALSKFVVEKGAQVGL
AFDGDGDRCIAVDELGNIIDGDKIMYICGKFLSERGKLKQDTVVTTVMSNLGLYKALEAAGLHSKQTQVGDRYVVEEMLK
DGYNLGGEQSGHVVFLDFNTTGDGMLTGIQLLHVMKETGKKLSELAAEVTTYPQKLVNVKVQDKKAALNNDKIKAVIKDV
EDEMAGDGRVLVRPSGTQDLLRVMAEAKTDELVSAYVDRIVDVVKAEVGIE

Sequences:

>Translated_451_residues
MKYFGTDGVRGIANSGLTPEMAFRLGRAGGYVLTEHAENKSTQPRVLVARDTRISGQMLEEALIAGLLSAGIEVLRLGVI
TTPGVAYLVRIQDADAGVMISASHNPVEDNGIKFFGGDGFKLSDAKEEEIEELLDQPKDTLPRPAAEGLGTVADFPEGNL
KYSQFLEQTIPDDLSGIHLAVDGANGSTSNLVSRIFADLNVEFDTMATAPDGLNINKGVGSTHPEALSKFVVEKGAQVGL
AFDGDGDRCIAVDELGNIIDGDKIMYICGKFLSERGKLKQDTVVTTVMSNLGLYKALEAAGLHSKQTQVGDRYVVEEMLK
DGYNLGGEQSGHVVFLDFNTTGDGMLTGIQLLHVMKETGKKLSELAAEVTTYPQKLVNVKVQDKKAALNNDKIKAVIKDV
EDEMAGDGRVLVRPSGTQDLLRVMAEAKTDELVSAYVDRIVDVVKAEVGIE
>Mature_451_residues
MKYFGTDGVRGIANSGLTPEMAFRLGRAGGYVLTEHAENKSTQPRVLVARDTRISGQMLEEALIAGLLSAGIEVLRLGVI
TTPGVAYLVRIQDADAGVMISASHNPVEDNGIKFFGGDGFKLSDAKEEEIEELLDQPKDTLPRPAAEGLGTVADFPEGNL
KYSQFLEQTIPDDLSGIHLAVDGANGSTSNLVSRIFADLNVEFDTMATAPDGLNINKGVGSTHPEALSKFVVEKGAQVGL
AFDGDGDRCIAVDELGNIIDGDKIMYICGKFLSERGKLKQDTVVTTVMSNLGLYKALEAAGLHSKQTQVGDRYVVEEMLK
DGYNLGGEQSGHVVFLDFNTTGDGMLTGIQLLHVMKETGKKLSELAAEVTTYPQKLVNVKVQDKKAALNNDKIKAVIKDV
EDEMAGDGRVLVRPSGTQDLLRVMAEAKTDELVSAYVDRIVDVVKAEVGIE

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=449, Percent_Identity=43.2071269487751, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1788361, Length=457, Percent_Identity=26.0393873085339, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_LACPL (Q88YE8)

Other databases:

- EMBL:   AL935254
- RefSeq:   NP_784562.1
- ProteinModelPortal:   Q88YE8
- GeneID:   1063935
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0820
- NMPDR:   fig|220668.1.peg.696
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14316
- BioCyc:   LPLA220668:LP_0820-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR018247
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48377; Mature: 48377

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00710 PGM_PMM; PS00018 EF_HAND_1

Important sites: ACT_SITE 103-103

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYFGTDGVRGIANSGLTPEMAFRLGRAGGYVLTEHAENKSTQPRVLVARDTRISGQMLE
CCCCCCCCCCHHHCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHH
EALIAGLLSAGIEVLRLGVITTPGVAYLVRIQDADAGVMISASHNPVEDNGIKFFGGDGF
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCEEEECCCCC
KLSDAKEEEIEELLDQPKDTLPRPAAEGLGTVADFPEGNLKYSQFLEQTIPDDLSGIHLA
CCCCCCHHHHHHHHHCCHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE
VDGANGSTSNLVSRIFADLNVEFDTMATAPDGLNINKGVGSTHPEALSKFVVEKGAQVGL
EECCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEE
AFDGDGDRCIAVDELGNIIDGDKIMYICGKFLSERGKLKQDTVVTTVMSNLGLYKALEAA
EEECCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
GLHSKQTQVGDRYVVEEMLKDGYNLGGEQSGHVVFLDFNTTGDGMLTGIQLLHVMKETGK
CCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
KLSELAAEVTTYPQKLVNVKVQDKKAALNNDKIKAVIKDVEDEMAGDGRVLVRPSGTQDL
HHHHHHHHHHHHHHHHHEEEEECHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
LRVMAEAKTDELVSAYVDRIVDVVKAEVGIE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYFGTDGVRGIANSGLTPEMAFRLGRAGGYVLTEHAENKSTQPRVLVARDTRISGQMLE
CCCCCCCCCCHHHCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHH
EALIAGLLSAGIEVLRLGVITTPGVAYLVRIQDADAGVMISASHNPVEDNGIKFFGGDGF
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCEEEECCCCC
KLSDAKEEEIEELLDQPKDTLPRPAAEGLGTVADFPEGNLKYSQFLEQTIPDDLSGIHLA
CCCCCCHHHHHHHHHCCHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE
VDGANGSTSNLVSRIFADLNVEFDTMATAPDGLNINKGVGSTHPEALSKFVVEKGAQVGL
EECCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEE
AFDGDGDRCIAVDELGNIIDGDKIMYICGKFLSERGKLKQDTVVTTVMSNLGLYKALEAA
EEECCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
GLHSKQTQVGDRYVVEEMLKDGYNLGGEQSGHVVFLDFNTTGDGMLTGIQLLHVMKETGK
CCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
KLSELAAEVTTYPQKLVNVKVQDKKAALNNDKIKAVIKDVEDEMAGDGRVLVRPSGTQDL
HHHHHHHHHHHHHHHHHEEEEECHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
LRVMAEAKTDELVSAYVDRIVDVVKAEVGIE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12566566