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The map label for this gene is galU [H]

Identifier: 28377616

GI number: 28377616

Start: 691787

End: 692707

Strand: Direct

Name: galU [H]

Synonym: lp_0757

Alternate gene names: 28377616

Gene position: 691787-692707 (Clockwise)

Preceding gene: 28377615

Following gene: 28377618

Centisome position: 20.91

GC content: 42.45

Gene sequence:

>921_bases
ATGTCAAAAGTTAGAAAAGCCGTTATCCCAGCGGCCGGATTAGGAACACGGTTTTTGCCTGCTACTAAGGCGATGCCTAA
AGAAATGTTACCAATCGTTGATAAACCAACGATTCAGTTCATTGTTGACGAAGCTCGTAAATCGGGGATCGAAGACATTG
TTATCGTCACGGGTAAGAGCAAGCGTAGTATTGAAGATTACTATGATTCTAACCCAGAATTAGAGGATAACTTACGGGCT
AAGCACAAGGAAGAAATGCTCAAGCTGGTTCAAGAAACCACAGACATTAACTTGTACTTTATCCGGCAATCACACCCACG
TGGTTTGGGCGATGCCGTTTTAACGGCTAAAGCTTTCGTTGGTGACGAACCTTTCGTCGTCATGCTTGGTGATGATTTAA
TGGAAGACAAAGTACCGTTAACCAAACAGTTAATGAATAGCTATGACAAGACACATGCGTCAACGTTAGCTGTTATGAAG
GTTCCTCATGAGGAAGTTTCTAAGTATGGGGTTATCAATCCTGAAAGTGAAAAGGAACCGGGCCTATACAACGTTAATAA
CTTTGTTGAAAAGCCATCACCTGAAGACGCGCCTAGTGATCTTGCTATCATTGGTCGTTACTTATTAACACCAGAAATTT
TTGATGTTCTTGAAAACCAAAAACCTGGTAAGGGTGACGAAATTCAATTGACGGATGCCATTGATACGTTGAACAAGACT
CAGCGGGTCTTTGCCCATGAATTTAAGGGGACTCGGCACGATGTTGGCTACAAGTTTGGCTACTTGAAGACGACGATCGA
ATACGGGTTAACTCATCCGGATGTTAAGGCTGACTTGCGGACTTACATCAAGGATCTTGGTGCTAAGTTATCTAAAGAAG
ATAGCGCCGCTCCTAAAACAACGAAGAAACCAACTAAATAA

Upstream 100 bases:

>100_bases
ATTAAGGAAGTCATTCCACAATTGATGCGGCGCGAGGGGAAACCTGAGATTCAGTAGGAATTTCCAAACTAATTTCACTA
TTTTTAGGAGGATTTATCAC

Downstream 100 bases:

>100_bases
TACTTGATTAATTAAAACAACCGTGAAATCTATTAAGATTTCACGGTTGTTTTTAGTTAACTGCTGAATAATTGCGATTC
ACTAATTAAGCTGGCACCTA

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase 1; UDP-glucose pyrophosphorylase 1; UDPGP 1; Uridine diphosphoglucose pyrophosphorylase 1 [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSKVRKAVIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQFIVDEARKSGIEDIVIVTGKSKRSIEDYYDSNPELEDNLRA
KHKEEMLKLVQETTDINLYFIRQSHPRGLGDAVLTAKAFVGDEPFVVMLGDDLMEDKVPLTKQLMNSYDKTHASTLAVMK
VPHEEVSKYGVINPESEKEPGLYNVNNFVEKPSPEDAPSDLAIIGRYLLTPEIFDVLENQKPGKGDEIQLTDAIDTLNKT
QRVFAHEFKGTRHDVGYKFGYLKTTIEYGLTHPDVKADLRTYIKDLGAKLSKEDSAAPKTTKKPTK

Sequences:

>Translated_306_residues
MSKVRKAVIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQFIVDEARKSGIEDIVIVTGKSKRSIEDYYDSNPELEDNLRA
KHKEEMLKLVQETTDINLYFIRQSHPRGLGDAVLTAKAFVGDEPFVVMLGDDLMEDKVPLTKQLMNSYDKTHASTLAVMK
VPHEEVSKYGVINPESEKEPGLYNVNNFVEKPSPEDAPSDLAIIGRYLLTPEIFDVLENQKPGKGDEIQLTDAIDTLNKT
QRVFAHEFKGTRHDVGYKFGYLKTTIEYGLTHPDVKADLRTYIKDLGAKLSKEDSAAPKTTKKPTK
>Mature_305_residues
SKVRKAVIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQFIVDEARKSGIEDIVIVTGKSKRSIEDYYDSNPELEDNLRAK
HKEEMLKLVQETTDINLYFIRQSHPRGLGDAVLTAKAFVGDEPFVVMLGDDLMEDKVPLTKQLMNSYDKTHASTLAVMKV
PHEEVSKYGVINPESEKEPGLYNVNNFVEKPSPEDAPSDLAIIGRYLLTPEIFDVLENQKPGKGDEIQLTDAIDTLNKTQ
RVFAHEFKGTRHDVGYKFGYLKTTIEYGLTHPDVKADLRTYIKDLGAKLSKEDSAAPKTTKKPTK

Specific function: May Play A Role In Stationary Phase Survival. [C]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=296, Percent_Identity=43.5810810810811, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1788355, Length=291, Percent_Identity=40.5498281786942, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1788351, Length=262, Percent_Identity=25.1908396946565, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790224, Length=229, Percent_Identity=24.4541484716157, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320148, Length=265, Percent_Identity=25.2830188679245, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355443, Length=269, Percent_Identity=24.5353159851301, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24644084, Length=269, Percent_Identity=24.5353159851301, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 34249; Mature: 34117

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVRKAVIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQFIVDEARKSGIEDIVIVTGKS
CCCHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCC
KRSIEDYYDSNPELEDNLRAKHKEEMLKLVQETTDINLYFIRQSHPRGLGDAVLTAKAFV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHC
GDEPFVVMLGDDLMEDKVPLTKQLMNSYDKTHASTLAVMKVPHEEVSKYGVINPESEKEP
CCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHEEEEEECCHHHHHHCCCCCCCCCCCC
GLYNVNNFVEKPSPEDAPSDLAIIGRYLLTPEIFDVLENQKPGKGDEIQLTDAIDTLNKT
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHH
QRVFAHEFKGTRHDVGYKFGYLKTTIEYGLTHPDVKADLRTYIKDLGAKLSKEDSAAPKT
HHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
TKKPTK
CCCCCC
>Mature Secondary Structure 
SKVRKAVIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQFIVDEARKSGIEDIVIVTGKS
CCHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCC
KRSIEDYYDSNPELEDNLRAKHKEEMLKLVQETTDINLYFIRQSHPRGLGDAVLTAKAFV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHC
GDEPFVVMLGDDLMEDKVPLTKQLMNSYDKTHASTLAVMKVPHEEVSKYGVINPESEKEP
CCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHEEEEEECCHHHHHHCCCCCCCCCCCC
GLYNVNNFVEKPSPEDAPSDLAIIGRYLLTPEIFDVLENQKPGKGDEIQLTDAIDTLNKT
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHH
QRVFAHEFKGTRHDVGYKFGYLKTTIEYGLTHPDVKADLRTYIKDLGAKLSKEDSAAPKT
HHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
TKKPTK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]