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The map label for this gene is lgt

Identifier: 28377614

GI number: 28377614

Start: 689861

End: 690709

Strand: Direct

Name: lgt

Synonym: lp_0755

Alternate gene names: 28377614

Gene position: 689861-690709 (Clockwise)

Preceding gene: 28377613

Following gene: 28377615

Centisome position: 20.85

GC content: 47.35

Gene sequence:

>849_bases
GTGAATACCGTTTTAGGGGCACTTAACCCAATTGCACTGCGGTTAGGACCAATTCAGGTCCATTGGTACGGCGTCATTAT
TGCTAGTGCCGTCGTCATTGCGGTTGCACTAGCAGTACGTGAAGGTCAGCGACGGGGTGTTCGGCCCGATGACATTTACG
ATATGATTTTATGGGCACTTCCGTTTACTTTAATTGCGGCGCGGACTTACTATGTGATTTTCCAGTGGTCATATTATCGT
CAGAATCCCGGTGAAATCATCCGTATCTGGGATGGTGGAATTGCCATCTATGGTGGCTTGATTGGCGCCGGAATTGTGGT
CATTTTATTCTGTCGGTCACGCTTTATCCCAACTTGGCTAATGCTTGATATTGCCGCACCAACGGTGATTATGGGCCAAG
GTATTGGTCGCTGGGGTAACTTTATGAACCAGGAGGCTTTTGGTCGAGTGACTAGTCTGAGTTTCTTACAAGGCTTGCAC
TTACCTGATTGGCTGATTAACCAGATGTATATCCGTGGCGCGTATCGGCAACCAACATTCTTGTATGAGTCGGTATGGGA
TCTATTAGGATTTGCCTTACTGATGCTCACGCGTCATCGCACACATTGGTATAAGCAGGGTGATGTCTTCTTGACTTATG
TTGCTTGGTACGCCTTTGGCCGCTTCTTCACAGAAGGGATGCGGACTGACTCGCTCATGCTATTTAACGTTATTCGGGTC
TCACAAGCGTTGTCAGTGGTACTGTTCTTTGGTAGCATTGGCTTAATGATCTGGCGCCGGCATCACAATCCGAATAATCG
TTGGTATTTAGCGGGTTCTGGTCAAAAGGTTGTCGCAGAAAATAAGTAG

Upstream 100 bases:

>100_bases
GGGCTACGATGCGACCAAGGTCTTTGACGATAACTTGAACAAGTTGATCAAAACGAATTCCGTGCATGATTCTCACAAGT
AATAAGGAGATGGCAGTAGC

Downstream 100 bases:

>100_bases
ATTAGAGGGTTATTTGAATGATGAAAAAAATTGCCGTTTTAGGTGCTGGCTCATGGGGTAGCATTTTGGCAAATCTGTTG
GATGAAAATGGCCACTCAGT

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNTVLGALNPIALRLGPIQVHWYGVIIASAVVIAVALAVREGQRRGVRPDDIYDMILWALPFTLIAARTYYVIFQWSYYR
QNPGEIIRIWDGGIAIYGGLIGAGIVVILFCRSRFIPTWLMLDIAAPTVIMGQGIGRWGNFMNQEAFGRVTSLSFLQGLH
LPDWLINQMYIRGAYRQPTFLYESVWDLLGFALLMLTRHRTHWYKQGDVFLTYVAWYAFGRFFTEGMRTDSLMLFNVIRV
SQALSVVLFFGSIGLMIWRRHHNPNNRWYLAGSGQKVVAENK

Sequences:

>Translated_282_residues
MNTVLGALNPIALRLGPIQVHWYGVIIASAVVIAVALAVREGQRRGVRPDDIYDMILWALPFTLIAARTYYVIFQWSYYR
QNPGEIIRIWDGGIAIYGGLIGAGIVVILFCRSRFIPTWLMLDIAAPTVIMGQGIGRWGNFMNQEAFGRVTSLSFLQGLH
LPDWLINQMYIRGAYRQPTFLYESVWDLLGFALLMLTRHRTHWYKQGDVFLTYVAWYAFGRFFTEGMRTDSLMLFNVIRV
SQALSVVLFFGSIGLMIWRRHHNPNNRWYLAGSGQKVVAENK
>Mature_282_residues
MNTVLGALNPIALRLGPIQVHWYGVIIASAVVIAVALAVREGQRRGVRPDDIYDMILWALPFTLIAARTYYVIFQWSYYR
QNPGEIIRIWDGGIAIYGGLIGAGIVVILFCRSRFIPTWLMLDIAAPTVIMGQGIGRWGNFMNQEAFGRVTSLSFLQGLH
LPDWLINQMYIRGAYRQPTFLYESVWDLLGFALLMLTRHRTHWYKQGDVFLTYVAWYAFGRFFTEGMRTDSLMLFNVIRV
SQALSVVLFFGSIGLMIWRRHHNPNNRWYLAGSGQKVVAENK

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=279, Percent_Identity=26.1648745519713, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_LACPL (Q88YK2)

Other databases:

- EMBL:   AL935254
- RefSeq:   NP_784506.1
- GeneID:   1063666
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0755
- NMPDR:   fig|220668.1.peg.640
- HOGENOM:   HBG450278
- OMA:   CARAYYV
- ProtClustDB:   PRK00052
- BioCyc:   LPLA220668:LP_0755-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 32318; Mature: 32318

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xceb3fa0)-; HASH(0xd4fa354)-; HASH(0xcc82d74)-; HASH(0xcf94b70)-; HASH(0xc1e6ff4)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVLGALNPIALRLGPIQVHWYGVIIASAVVIAVALAVREGQRRGVRPDDIYDMILWAL
CCCCHHCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
PFTLIAARTYYVIFQWSYYRQNPGEIIRIWDGGIAIYGGLIGAGIVVILFCRSRFIPTWL
HHHHHHHHHEEEEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
MLDIAAPTVIMGQGIGRWGNFMNQEAFGRVTSLSFLQGLHLPDWLINQMYIRGAYRQPTF
HHHHCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHH
LYESVWDLLGFALLMLTRHRTHWYKQGDVFLTYVAWYAFGRFFTEGMRTDSLMLFNVIRV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SQALSVVLFFGSIGLMIWRRHHNPNNRWYLAGSGQKVVAENK
HHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCEEECCCH
>Mature Secondary Structure
MNTVLGALNPIALRLGPIQVHWYGVIIASAVVIAVALAVREGQRRGVRPDDIYDMILWAL
CCCCHHCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
PFTLIAARTYYVIFQWSYYRQNPGEIIRIWDGGIAIYGGLIGAGIVVILFCRSRFIPTWL
HHHHHHHHHEEEEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
MLDIAAPTVIMGQGIGRWGNFMNQEAFGRVTSLSFLQGLHLPDWLINQMYIRGAYRQPTF
HHHHCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHH
LYESVWDLLGFALLMLTRHRTHWYKQGDVFLTYVAWYAFGRFFTEGMRTDSLMLFNVIRV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SQALSVVLFFGSIGLMIWRRHHNPNNRWYLAGSGQKVVAENK
HHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCEEECCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12566566