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The map label for this gene is rrp3 [H]

Identifier: 28377603

GI number: 28377603

Start: 680516

End: 681244

Strand: Direct

Name: rrp3 [H]

Synonym: lp_0743

Alternate gene names: 28377603

Gene position: 680516-681244 (Clockwise)

Preceding gene: 28377602

Following gene: 28377604

Centisome position: 20.57

GC content: 46.5

Gene sequence:

>729_bases
ATGACCATGGATAAGATTTTAGTGGTAGACGACGAACCAGCTATCGTCACGTTATTATCATATAACTTGAAGCAGGCGGG
GTACGAAGTTGTGACGGCGACGGATGGTGCGGACGCGTTGTCATTAGGCCTGGCCCAATCATTTACATGTATTTTGTTAG
ATTTGATGTTGCCGAAACTCGATGGAATGGAAGTAACAAAAAAGTTACGACAAGAAAAGGTTCAGACGCCTATTATTATT
GTGACGGCTAAAAATGATGAGTTTGATAAAGTGTTCGGCTTGGAATTAGGTGCGGACGATTATATAACCAAGCCGTTTTC
ACCCCGCGAAGTGCTCGCTCGGATCAAAGCAGTTATTCGGCGGACAACGCCGGACGAGCCCGTGACACCACCGGCACCCA
TGCCGCCTGCTAATCGTGCGGTAATGCTTGTTGGTGATTTACAGATTGATCAAAACAAATACCGAGTCGCGCGCAACGGG
AAAAATATCAGCTTGACACCAAAGGAATTTGAATTACTTGTGTATTTTGTTGAACGAGAAGGTCGGGTTCTCAGTCGTGA
TGCGATTTTAAATCACGTCTGGGGCTACGACTATGCTAGTGAGACGCGGATCGTTGATATTCACATCTCACATTTACGTG
AAAAGATTGAAGCAGATCCCAAGCAGCCACGGTTGATCAGGACGGTCCGGGGTTTTGGCTACGAATTTGTGGGTGACGGC
CATGCATAA

Upstream 100 bases:

>100_bases
TGCGCAATCGGCAACAGGAATTAATTATTACCGAAACGGCGATCTATAATGGCGCCCCACACGAGTTAGGAATTGTGTTA
TTCACTGATCAGGAGGATTA

Downstream 100 bases:

>100_bases
TCGCTGGCAACAGACGACACGGTTATTGCTCATGGAAAATGTGTTACTGGTTCTGATCGTGTTGGTCGTGTTGCAGCACT
TTTCGCCAATTAAGTGGTCC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTMDKILVVDDEPAIVTLLSYNLKQAGYEVVTATDGADALSLGLAQSFTCILLDLMLPKLDGMEVTKKLRQEKVQTPIII
VTAKNDEFDKVFGLELGADDYITKPFSPREVLARIKAVIRRTTPDEPVTPPAPMPPANRAVMLVGDLQIDQNKYRVARNG
KNISLTPKEFELLVYFVEREGRVLSRDAILNHVWGYDYASETRIVDIHISHLREKIEADPKQPRLIRTVRGFGYEFVGDG
HA

Sequences:

>Translated_242_residues
MTMDKILVVDDEPAIVTLLSYNLKQAGYEVVTATDGADALSLGLAQSFTCILLDLMLPKLDGMEVTKKLRQEKVQTPIII
VTAKNDEFDKVFGLELGADDYITKPFSPREVLARIKAVIRRTTPDEPVTPPAPMPPANRAVMLVGDLQIDQNKYRVARNG
KNISLTPKEFELLVYFVEREGRVLSRDAILNHVWGYDYASETRIVDIHISHLREKIEADPKQPRLIRTVRGFGYEFVGDG
HA
>Mature_241_residues
TMDKILVVDDEPAIVTLLSYNLKQAGYEVVTATDGADALSLGLAQSFTCILLDLMLPKLDGMEVTKKLRQEKVQTPIIIV
TAKNDEFDKVFGLELGADDYITKPFSPREVLARIKAVIRRTTPDEPVTPPAPMPPANRAVMLVGDLQIDQNKYRVARNGK
NISLTPKEFELLVYFVEREGRVLSRDAILNHVWGYDYASETRIVDIHISHLREKIEADPKQPRLIRTVRGFGYEFVGDGH
A

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=41.1016949152542, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=40.5982905982906, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=37.1794871794872, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=38.8185654008439, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=37.3913043478261, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786911, Length=239, Percent_Identity=35.1464435146443, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=38.7234042553192, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790860, Length=238, Percent_Identity=33.1932773109244, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=32.7659574468085, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790863, Length=240, Percent_Identity=31.25, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=32.6086956521739, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=34.0425531914894, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=31.0344827586207, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI145693140, Length=242, Percent_Identity=29.7520661157025, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788550, Length=105, Percent_Identity=34.2857142857143, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=38.2352941176471, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=32.4561403508772, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=31.8181818181818, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=30.6930693069307, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=34.9514563106796, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27178; Mature: 27047

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMDKILVVDDEPAIVTLLSYNLKQAGYEVVTATDGADALSLGLAQSFTCILLDLMLPKL
CCCCCEEEECCCCCEEEEEEHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
DGMEVTKKLRQEKVQTPIIIVTAKNDEFDKVFGLELGADDYITKPFSPREVLARIKAVIR
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RTTPDEPVTPPAPMPPANRAVMLVGDLQIDQNKYRVARNGKNISLTPKEFELLVYFVERE
CCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCEEECHHHEEEEEEEEECC
GRVLSRDAILNHVWGYDYASETRIVDIHISHLREKIEADPKQPRLIRTVRGFGYEFVGDG
CCEEHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCC
HA
CC
>Mature Secondary Structure 
TMDKILVVDDEPAIVTLLSYNLKQAGYEVVTATDGADALSLGLAQSFTCILLDLMLPKL
CCCCEEEECCCCCEEEEEEHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
DGMEVTKKLRQEKVQTPIIIVTAKNDEFDKVFGLELGADDYITKPFSPREVLARIKAVIR
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RTTPDEPVTPPAPMPPANRAVMLVGDLQIDQNKYRVARNGKNISLTPKEFELLVYFVERE
CCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCEEECHHHEEEEEEEEECC
GRVLSRDAILNHVWGYDYASETRIVDIHISHLREKIEADPKQPRLIRTVRGFGYEFVGDG
CCEEHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCC
HA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]