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The map label for this gene is rex

Identifier: 28377588

GI number: 28377588

Start: 663325

End: 664002

Strand: Direct

Name: rex

Synonym: lp_0725

Alternate gene names: 28377588

Gene position: 663325-664002 (Clockwise)

Preceding gene: 28377586

Following gene: 28377590

Centisome position: 20.05

GC content: 42.04

Gene sequence:

>678_bases
ATGGCAGAAACAAAAATTCCACGGGCAACGGCAAAACGGTTACCGATTTATTACCGCTATTTAAATATCTTGCTAGATGC
AGATAAGAAGCGGGTCTCATCGACCGAGTTGTCCGAGGCGGTTAAAGTAGATTCAGCAACGATTCGGCGAGATTTCTCGT
ATTTTGGGGCGCTCGGCAAACGAGGGTATGGATACGATGTTGAAACGTTACTTGCATTTTTCAAAAAGATTTTAAATCAA
GACACCTTAACGAATGTTGCTTTAATTGGGGTCGGTAATTTGGGCCACGCCCTACTGAACTTTAATTTTCACAAAAACAG
TAATGTCCGCATTTCAGCAGCATTTGATGTCAACGAGGCGATTGCCAATACAGTCCAAAGTGGGGTTCCAGTGTACCCAA
TGACGGAGCTCAAAAAGCAATTGATCGAACAACAGATTGAGATTGCTATCTTAACGGTGCCAACCACGGTTGTTCAGAAA
ATTACCGATGACTTGGTTGATGCAAACGTCAAAGGAATCATGAACTTTACGCCGTTACGAATCTCCGTTCCTGAGACAGT
ACGGGTTCAGAACGTTGATTTGACCAACGAATTACAAACATTGATCTACTTCATTGAACATTACGGTCAGCAATTAGGTG
ACAATGGTAATGACGATGAAAATGAGACTGAAGATTAA

Upstream 100 bases:

>100_bases
TTATTCGGAATAATAAGTAATTATTATTTCACAAAGTCACGCGTTATGCTAGAATAGTGTCAGCAAATTCACAAACTTTT
AATTAGGAGGACACGTCCGA

Downstream 100 bases:

>100_bases
TAACTCGCTTTATCTTTGAAATTAAATGGCTATAAAAAGGCTTCTCTGAATTATTCAGGGAAGCTTTTTTAACATACTTA
GATCACGAATCATTGATTGT

Product: redox-sensing transcriptional repressor Rex

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAETKIPRATAKRLPIYYRYLNILLDADKKRVSSTELSEAVKVDSATIRRDFSYFGALGKRGYGYDVETLLAFFKKILNQ
DTLTNVALIGVGNLGHALLNFNFHKNSNVRISAAFDVNEAIANTVQSGVPVYPMTELKKQLIEQQIEIAILTVPTTVVQK
ITDDLVDANVKGIMNFTPLRISVPETVRVQNVDLTNELQTLIYFIEHYGQQLGDNGNDDENETED

Sequences:

>Translated_225_residues
MAETKIPRATAKRLPIYYRYLNILLDADKKRVSSTELSEAVKVDSATIRRDFSYFGALGKRGYGYDVETLLAFFKKILNQ
DTLTNVALIGVGNLGHALLNFNFHKNSNVRISAAFDVNEAIANTVQSGVPVYPMTELKKQLIEQQIEIAILTVPTTVVQK
ITDDLVDANVKGIMNFTPLRISVPETVRVQNVDLTNELQTLIYFIEHYGQQLGDNGNDDENETED
>Mature_224_residues
AETKIPRATAKRLPIYYRYLNILLDADKKRVSSTELSEAVKVDSATIRRDFSYFGALGKRGYGYDVETLLAFFKKILNQD
TLTNVALIGVGNLGHALLNFNFHKNSNVRISAAFDVNEAIANTVQSGVPVYPMTELKKQLIEQQIEIAILTVPTTVVQKI
TDDLVDANVKGIMNFTPLRISVPETVRVQNVDLTNELQTLIYFIEHYGQQLGDNGNDDENETED

Specific function: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state

COG id: COG2344

COG function: function code R; AT-rich DNA-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory rex family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): REX_LACPL (Q88YM8)

Other databases:

- EMBL:   AL935253
- RefSeq:   NP_784480.1
- ProteinModelPortal:   Q88YM8
- SMR:   Q88YM8
- GeneID:   1063358
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0725
- NMPDR:   fig|220668.1.peg.614
- HOGENOM:   HBG482264
- OMA:   TRGVGYD
- ProtClustDB:   PRK05472
- BioCyc:   LPLA220668:LP_0725-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01131
- InterPro:   IPR003781
- InterPro:   IPR016040
- InterPro:   IPR009718
- InterPro:   IPR022876
- InterPro:   IPR011991
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00881

Pfam domain/function: PF02629 CoA_binding; PF06971 Put_DNA-bind_N

EC number: NA

Molecular weight: Translated: 25214; Mature: 25083

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETKIPRATAKRLPIYYRYLNILLDADKKRVSSTELSEAVKVDSATIRRDFSYFGALGK
CCCCCCCHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGYGYDVETLLAFFKKILNQDTLTNVALIGVGNLGHALLNFNFHKNSNVRISAAFDVNEA
CCCCCCHHHHHHHHHHHHCCCHHHHEEEEEECCCCHHHEEEEECCCCCEEEEEECCHHHH
IANTVQSGVPVYPMTELKKQLIEQQIEIAILTVPTTVVQKITDDLVDANVKGIMNFTPLR
HHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHCCCHHHCCCCCCEE
ISVPETVRVQNVDLTNELQTLIYFIEHYGQQLGDNGNDDENETED
EECCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AETKIPRATAKRLPIYYRYLNILLDADKKRVSSTELSEAVKVDSATIRRDFSYFGALGK
CCCCCCHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGYGYDVETLLAFFKKILNQDTLTNVALIGVGNLGHALLNFNFHKNSNVRISAAFDVNEA
CCCCCCHHHHHHHHHHHHCCCHHHHEEEEEECCCCHHHEEEEECCCCCEEEEEECCHHHH
IANTVQSGVPVYPMTELKKQLIEQQIEIAILTVPTTVVQKITDDLVDANVKGIMNFTPLR
HHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHCCCHHHCCCCCCEE
ISVPETVRVQNVDLTNELQTLIYFIEHYGQQLGDNGNDDENETED
EECCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566