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The map label for this gene is galE1 [H]

Identifier: 28377576

GI number: 28377576

Start: 650610

End: 651605

Strand: Direct

Name: galE1 [H]

Synonym: lp_0709

Alternate gene names: 28377576

Gene position: 650610-651605 (Clockwise)

Preceding gene: 28377575

Following gene: 28377583

Centisome position: 19.67

GC content: 46.59

Gene sequence:

>996_bases
ATGTCAATTTTAGTTTTAGGGGGAGCTGGCTACATTGGTTCTCACATGGTCGATCGGTTAGTAGAACACGGTACGGACGT
CGTGGTCGTTGATAATTTGGTCACGGGACACCGCGCTGCTGTTAATTCGGCGGCCAAGTTTTATCAGGGTGATTTGCGGG
ATGCGGATTTTTTGAATCACGTTTTTGATACTGAGGACATTGAAGCTGTCGTGCATTTTGCCGCCTTTTCAATCGTACCA
GAATCAATGAGTAAGCCACTGAAGTACTTTGATAACAATACTGGTGGGATGATCACGTTACTTGAAACGATGCAGGCCCA
TGATGTGAAGCAAATCGTCTTCTCATCAACGGCCGCTACTTATGGGACACCTAAGCAGATTCCAATTAAAGAAACTGATC
CACAGTTACCAATCAACCCGTATGGCGCTAGCAAGTTAATGATGGAACAAATTATGCACTGGGCGGACGTTGCCTATGGT
ATTAAGTTTGTCGCGTTACGTTACTTTAACGTTGCGGGTGCCAAGCCAGATGGCAGTATTGGCGAAGATCATGGCCCCGA
AACACATCTGGTTCCAATCATTTTACAAGTTGCGCAAGGAAAACGCGATGAACTTAAAATCTTCGGCGATGACTATAATA
CGCCGGATGGGACGAATGTGCGTGACTATGTGCATGTTGTCGACTTAGCTGATGCACATATCTTGGCTTTGAAGTACTTG
GCTGCAGGAAATGACAGTAATGCCTTTAACCTGGGTTCTTCAACTGGTTTCTCTAACAAACAAATGTTAGCGGCTGCTCG
TGAAGTTACCGGGCAACCAATTCCAGCTAAGCTAGCACCACGGCGGCCTGGTGATCCAGACTCATTGGTTGCGGCGAGTG
ATAAGGCGCGTGACGTGCTAGGTTGGCAACCAAATTATGACAATGTTAACGATATTATTGAAACAGCGTGGGCTTGGACG
CAGAAGCATCCCAATGGCTACGATGATCGTGACTAG

Upstream 100 bases:

>100_bases
TGGTCATGAGCGACTTGGTCGATTAGAACGCACGTTTTTATTAGAGTCGCTAGCGATTCAGTATGCTATGATTAATACAT
CCATACAGGGGAGGTTCATT

Downstream 100 bases:

>100_bases
TATCGGTTAGCTGATAATTGAAAGCGGCTTTGAAATCTCGTCAATAGATTTCAAAGCCGCTTTTGTGGTCGTCAAAAAAG
GTGCATGTCAGGATTGAGTC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSILVLGGAGYIGSHMVDRLVEHGTDVVVVDNLVTGHRAAVNSAAKFYQGDLRDADFLNHVFDTEDIEAVVHFAAFSIVP
ESMSKPLKYFDNNTGGMITLLETMQAHDVKQIVFSSTAATYGTPKQIPIKETDPQLPINPYGASKLMMEQIMHWADVAYG
IKFVALRYFNVAGAKPDGSIGEDHGPETHLVPIILQVAQGKRDELKIFGDDYNTPDGTNVRDYVHVVDLADAHILALKYL
AAGNDSNAFNLGSSTGFSNKQMLAAAREVTGQPIPAKLAPRRPGDPDSLVAASDKARDVLGWQPNYDNVNDIIETAWAWT
QKHPNGYDDRD

Sequences:

>Translated_331_residues
MSILVLGGAGYIGSHMVDRLVEHGTDVVVVDNLVTGHRAAVNSAAKFYQGDLRDADFLNHVFDTEDIEAVVHFAAFSIVP
ESMSKPLKYFDNNTGGMITLLETMQAHDVKQIVFSSTAATYGTPKQIPIKETDPQLPINPYGASKLMMEQIMHWADVAYG
IKFVALRYFNVAGAKPDGSIGEDHGPETHLVPIILQVAQGKRDELKIFGDDYNTPDGTNVRDYVHVVDLADAHILALKYL
AAGNDSNAFNLGSSTGFSNKQMLAAAREVTGQPIPAKLAPRRPGDPDSLVAASDKARDVLGWQPNYDNVNDIIETAWAWT
QKHPNGYDDRD
>Mature_330_residues
SILVLGGAGYIGSHMVDRLVEHGTDVVVVDNLVTGHRAAVNSAAKFYQGDLRDADFLNHVFDTEDIEAVVHFAAFSIVPE
SMSKPLKYFDNNTGGMITLLETMQAHDVKQIVFSSTAATYGTPKQIPIKETDPQLPINPYGASKLMMEQIMHWADVAYGI
KFVALRYFNVAGAKPDGSIGEDHGPETHLVPIILQVAQGKRDELKIFGDDYNTPDGTNVRDYVHVVDLADAHILALKYLA
AGNDSNAFNLGSSTGFSNKQMLAAAREVTGQPIPAKLAPRRPGDPDSLVAASDKARDVLGWQPNYDNVNDIIETAWAWTQ
KHPNGYDDRD

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=40.8163265306122, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=40.8163265306122, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=40.8163265306122, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI7657641, Length=317, Percent_Identity=25.5520504731861, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=25.4838709677419, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI310132178, Length=370, Percent_Identity=24.0540540540541, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI310113012, Length=370, Percent_Identity=24.0540540540541, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=40.7624633431085, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI1790049, Length=289, Percent_Identity=30.7958477508651, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788353, Length=338, Percent_Identity=26.3313609467456, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=28.6567164179104, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=38.5057471264368, Blast_Score=224, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=38.2857142857143, Blast_Score=223, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI17539532, Length=324, Percent_Identity=26.5432098765432, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568069, Length=328, Percent_Identity=25, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115532424, Length=330, Percent_Identity=23.9393939393939, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=349, Percent_Identity=43.2664756446991, Blast_Score=257, Evalue=2e-69,
Organism=Drosophila melanogaster, GI19923002, Length=349, Percent_Identity=37.8223495702006, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI21356223, Length=311, Percent_Identity=26.6881028938907, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36150; Mature: 36019

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVLGGAGYIGSHMVDRLVEHGTDVVVVDNLVTGHRAAVNSAAKFYQGDLRDADFLNH
CEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
VFDTEDIEAVVHFAAFSIVPESMSKPLKYFDNNTGGMITLLETMQAHDVKQIVFSSTAAT
HCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCC
YGTPKQIPIKETDPQLPINPYGASKLMMEQIMHWADVAYGIKFVALRYFNVAGAKPDGSI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GEDHGPETHLVPIILQVAQGKRDELKIFGDDYNTPDGTNVRDYVHVVDLADAHILALKYL
CCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHEEHHHHCCHHHHHHHHH
AAGNDSNAFNLGSSTGFSNKQMLAAAREVTGQPIPAKLAPRRPGDPDSLVAASDKARDVL
HCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHEEECCCCHHHHC
GWQPNYDNVNDIIETAWAWTQKHPNGYDDRD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SILVLGGAGYIGSHMVDRLVEHGTDVVVVDNLVTGHRAAVNSAAKFYQGDLRDADFLNH
EEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
VFDTEDIEAVVHFAAFSIVPESMSKPLKYFDNNTGGMITLLETMQAHDVKQIVFSSTAAT
HCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCC
YGTPKQIPIKETDPQLPINPYGASKLMMEQIMHWADVAYGIKFVALRYFNVAGAKPDGSI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GEDHGPETHLVPIILQVAQGKRDELKIFGDDYNTPDGTNVRDYVHVVDLADAHILALKYL
CCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHEEHHHHCCHHHHHHHHH
AAGNDSNAFNLGSSTGFSNKQMLAAAREVTGQPIPAKLAPRRPGDPDSLVAASDKARDVL
HCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHEEECCCCHHHHC
GWQPNYDNVNDIIETAWAWTQKHPNGYDDRD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]