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The map label for this gene is mprF [H]

Identifier: 28377559

GI number: 28377559

Start: 634153

End: 636711

Strand: Direct

Name: mprF [H]

Synonym: lp_0690

Alternate gene names: 28377559

Gene position: 634153-636711 (Clockwise)

Preceding gene: 28377555

Following gene: 28377564

Centisome position: 19.17

GC content: 44.59

Gene sequence:

>2559_bases
ATGGGGATCATCAAAGCATTATTTGTATTCTCTGTCCTGTTATTTGTGATTACGGAAGTCGGCAAAATTGCGAAGGAAGT
CAGTGGCGCGCAGTTGGCGAATGCGCTTGCTTCGCAAAGCTGGTGGCATCTGTTAAGCATGGTCGTGATTGGTATTATCG
CAGTGACACCAATGCTGACGTATGACGTCATGATTACAAAGTTTTTACCCAACCACTATTCACTTGGCTATATCTTAAAA
GCTGGATGGATCACCAATACATTTACGAATATCGGTGGTTTTGGGGGCGTGCTGGGCGCCTCACTGCGTGCTAACTTTTA
TAATCGCGAAGCCACTAAGAAACAAATCGTGTTTGCCATTTCCAAGATCGCTTTGTTTTTAGTTTCGGGATTGTCATTAT
ATTGTATGATTTCACTCGTGCTAGTCTATGGCTTTGGCATTGGGAACATGTATGGCAGTTACTGGATCTGGCTCGTCGGT
GGTGCACTGTATTTTCCAGCCATCTTTATTTTTACACGAGTCAACGATTCGGAATTCTTCGATGGCCTTACGCTCGGCAA
CGTCGTTCGGTTATTGAGTGGGTCGTTTGGTGAATGGACTGGCTGTGTGCTGTTCTTCTTATTAATTGGAAACTTTATGG
GATTACCCATTGATTTTGCAGCGGTCGTGCCGTTATTCGTGATTGCTTCGGTTGTCGGTGAAGTGTCAATGGTACCCGGT
GGTATTGGGTCATTCGACGTTTTCATGATTTTTGGCCTCGGTGCGGTCGGAGTTTCTCGACCAGACGCAGTCGCATGGCT
CTTATTTTACCGGTTATTCTACTATATTATCCCGTTTGCCATCGGGTTGGTCTTATTCATCCATGACACCGGCCATCGCT
TAAACGTGCGCTTAGCGGGTATTCCTAAGCAGGCATTACAACGTGTTGCTCAGATGGTACTGACGGTTTTTCTCTATTTT
TCTGGTTTTCTGATGTTGTTGATGTCAACGGTCCCTAACTTTGCATATAACAATAAACTCTTCTTACAGTTTTATCCGTA
CACCTTTTTCTTTATTAATCAGGCCAGCAGTATTATTATGGCCTTCTTACTGATTGGGGTGGCGTTGGGAACTGCTGGCC
GGGTCAAAAAAGCTTTTTGGCCAACGGTGATTGTCCTGCTGATTGCAATTTTGAATACGATTCGCTGGCTCGTCGTTTAT
GATGCAATTTCGATGAAATTTGTGATTTTCTTGATTGTGATTCTAGCGCTAGTGGCTTTGTCGCGGCATGCTTATTATCG
TGATCGGTTGGCTTTTTCGTGGGGGCAAACGTTGTGGGTTAGCTGCGTGTATGTGGTGACCTTTATCTTGTATACGATTG
TGGGAGTCTATAACGCGCCCCAAATTCATCATCGGCATGCGATTCCTGAAGCTCTGTTCTTCCCATCACAAAAGCTCTGG
TTATTTGGGGTGATTGGGTTAGTCTTAGCGGCAATGATTTTGATTATTATGTACCGCTACTTTGCGAGTGGCTATAACGC
CCGATTGCGTCAAAAGATGGATGCGGCTCGGGTCAAACAAGTGATTGAAACTTATGGCGGCAATGAAATCTCACACTTGG
CTTATTTGAATGATAAGTTAGCATATTACTATCAAGTCGATGGGGTCGATCAACTGATTTTCTTATACCAACAGAAGGCC
GATAAACTGATTATTATGGGAGAGCCATTCGGTAATCAAGCGGTATTACAAGCTGCCTTGGAACAGTTATTGGATGACGC
AGATAGTGACGGTTGCTCGCTAGTCTTTTACGAAATTAGTGAGATGCTGACGATGCGCCTACACGAAATGGGCTTTGACT
TTATCAAAACCGGTGAAGAAGGGCACGTTAAATTGGCAGACTTTAGTTTGGCTGGTAAACGGCTACGGGGTGAACGGGCC
CTAATGAATAAGTTTACCCGGGATCACTATGAGTTTGCCATCTTGCAGCCACCGTTCAGTGCCGACGTTATGGCTGAATT
ACGAGCTGTTTCGGATAGTTGGTTAGCAGGTGAGACGGAAAAAGGATTCTCGCTCGGATTTTTTGATGAGCAGTATCTCA
ATCAGGCACCCGTAGCGGTCGTTTATGATCCTGACCACCGAATTGTCGCGTTTGCGAATATTATGCCGCAGGGAAATCAT
CAGACGACTTCAATTGACTTAATGCGGTCAAGCAAATCGGCGCCATCCGGCATTATGGACACGGTCTTTGTGCACCTATT
TGAACAGGCGCGTGACGATGGCTATGCTTATTTCAATATGGGAATGGCACCATTATCCGGTGTAGGGGTTTCACGCTACA
GTTTTATTCAAGAAAAAATTGCTCATTTAATTTACGAATATGGCTACCAGTTATATGGTTTTCAGGGATTACGGTCGTAC
AAAGAGAAGTATGTGACTGAGTGGGAACCGAAGTACATTGCGTACCGAAAACGTAATTCACTAATCTTCACCATTTTACA
ATTGCTACAAGTCGTTAATACCCGGGTACACAAGTCTGAGCGGCACCGGCCAGTATGGTTGTTGAAACGATTGAAATAA

Upstream 100 bases:

>100_bases
TATAAACAGGCTAAGATTGCGATAATAGAACAAACACACCAATGGGGGAATTTTTTTGAAGGCAACGTTACAGAAAATCG
GGACGGCACTCAATAAACGC

Downstream 100 bases:

>100_bases
CTGAATAGTATGTCATAAAGTAAGTATCGTTAATGACATAGCAAAATGCCCCATCACTGCGAGAAGCAATGATGGGGCAT
TTTATGATGACTTTAGAATT

Product: integral membrane protein (putative)

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 852; Mature: 851

Protein sequence:

>852_residues
MGIIKALFVFSVLLFVITEVGKIAKEVSGAQLANALASQSWWHLLSMVVIGIIAVTPMLTYDVMITKFLPNHYSLGYILK
AGWITNTFTNIGGFGGVLGASLRANFYNREATKKQIVFAISKIALFLVSGLSLYCMISLVLVYGFGIGNMYGSYWIWLVG
GALYFPAIFIFTRVNDSEFFDGLTLGNVVRLLSGSFGEWTGCVLFFLLIGNFMGLPIDFAAVVPLFVIASVVGEVSMVPG
GIGSFDVFMIFGLGAVGVSRPDAVAWLLFYRLFYYIIPFAIGLVLFIHDTGHRLNVRLAGIPKQALQRVAQMVLTVFLYF
SGFLMLLMSTVPNFAYNNKLFLQFYPYTFFFINQASSIIMAFLLIGVALGTAGRVKKAFWPTVIVLLIAILNTIRWLVVY
DAISMKFVIFLIVILALVALSRHAYYRDRLAFSWGQTLWVSCVYVVTFILYTIVGVYNAPQIHHRHAIPEALFFPSQKLW
LFGVIGLVLAAMILIIMYRYFASGYNARLRQKMDAARVKQVIETYGGNEISHLAYLNDKLAYYYQVDGVDQLIFLYQQKA
DKLIIMGEPFGNQAVLQAALEQLLDDADSDGCSLVFYEISEMLTMRLHEMGFDFIKTGEEGHVKLADFSLAGKRLRGERA
LMNKFTRDHYEFAILQPPFSADVMAELRAVSDSWLAGETEKGFSLGFFDEQYLNQAPVAVVYDPDHRIVAFANIMPQGNH
QTTSIDLMRSSKSAPSGIMDTVFVHLFEQARDDGYAYFNMGMAPLSGVGVSRYSFIQEKIAHLIYEYGYQLYGFQGLRSY
KEKYVTEWEPKYIAYRKRNSLIFTILQLLQVVNTRVHKSERHRPVWLLKRLK

Sequences:

>Translated_852_residues
MGIIKALFVFSVLLFVITEVGKIAKEVSGAQLANALASQSWWHLLSMVVIGIIAVTPMLTYDVMITKFLPNHYSLGYILK
AGWITNTFTNIGGFGGVLGASLRANFYNREATKKQIVFAISKIALFLVSGLSLYCMISLVLVYGFGIGNMYGSYWIWLVG
GALYFPAIFIFTRVNDSEFFDGLTLGNVVRLLSGSFGEWTGCVLFFLLIGNFMGLPIDFAAVVPLFVIASVVGEVSMVPG
GIGSFDVFMIFGLGAVGVSRPDAVAWLLFYRLFYYIIPFAIGLVLFIHDTGHRLNVRLAGIPKQALQRVAQMVLTVFLYF
SGFLMLLMSTVPNFAYNNKLFLQFYPYTFFFINQASSIIMAFLLIGVALGTAGRVKKAFWPTVIVLLIAILNTIRWLVVY
DAISMKFVIFLIVILALVALSRHAYYRDRLAFSWGQTLWVSCVYVVTFILYTIVGVYNAPQIHHRHAIPEALFFPSQKLW
LFGVIGLVLAAMILIIMYRYFASGYNARLRQKMDAARVKQVIETYGGNEISHLAYLNDKLAYYYQVDGVDQLIFLYQQKA
DKLIIMGEPFGNQAVLQAALEQLLDDADSDGCSLVFYEISEMLTMRLHEMGFDFIKTGEEGHVKLADFSLAGKRLRGERA
LMNKFTRDHYEFAILQPPFSADVMAELRAVSDSWLAGETEKGFSLGFFDEQYLNQAPVAVVYDPDHRIVAFANIMPQGNH
QTTSIDLMRSSKSAPSGIMDTVFVHLFEQARDDGYAYFNMGMAPLSGVGVSRYSFIQEKIAHLIYEYGYQLYGFQGLRSY
KEKYVTEWEPKYIAYRKRNSLIFTILQLLQVVNTRVHKSERHRPVWLLKRLK
>Mature_851_residues
GIIKALFVFSVLLFVITEVGKIAKEVSGAQLANALASQSWWHLLSMVVIGIIAVTPMLTYDVMITKFLPNHYSLGYILKA
GWITNTFTNIGGFGGVLGASLRANFYNREATKKQIVFAISKIALFLVSGLSLYCMISLVLVYGFGIGNMYGSYWIWLVGG
ALYFPAIFIFTRVNDSEFFDGLTLGNVVRLLSGSFGEWTGCVLFFLLIGNFMGLPIDFAAVVPLFVIASVVGEVSMVPGG
IGSFDVFMIFGLGAVGVSRPDAVAWLLFYRLFYYIIPFAIGLVLFIHDTGHRLNVRLAGIPKQALQRVAQMVLTVFLYFS
GFLMLLMSTVPNFAYNNKLFLQFYPYTFFFINQASSIIMAFLLIGVALGTAGRVKKAFWPTVIVLLIAILNTIRWLVVYD
AISMKFVIFLIVILALVALSRHAYYRDRLAFSWGQTLWVSCVYVVTFILYTIVGVYNAPQIHHRHAIPEALFFPSQKLWL
FGVIGLVLAAMILIIMYRYFASGYNARLRQKMDAARVKQVIETYGGNEISHLAYLNDKLAYYYQVDGVDQLIFLYQQKAD
KLIIMGEPFGNQAVLQAALEQLLDDADSDGCSLVFYEISEMLTMRLHEMGFDFIKTGEEGHVKLADFSLAGKRLRGERAL
MNKFTRDHYEFAILQPPFSADVMAELRAVSDSWLAGETEKGFSLGFFDEQYLNQAPVAVVYDPDHRIVAFANIMPQGNHQ
TTSIDLMRSSKSAPSGIMDTVFVHLFEQARDDGYAYFNMGMAPLSGVGVSRYSFIQEKIAHLIYEYGYQLYGFQGLRSYK
EKYVTEWEPKYIAYRKRNSLIFTILQLLQVVNTRVHKSERHRPVWLLKRLK

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 96161; Mature: 96030

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHCCC
>Mature Secondary Structure 
GIIKALFVFSVLLFVITEVGKIAKEVSGAQLANALASQSWWHLLSMVVIGIIAVTPMLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]