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The map label for this gene is hslO

Identifier: 28377432

GI number: 28377432

Start: 498768

End: 499655

Strand: Direct

Name: hslO

Synonym: lp_0548

Alternate gene names: 28377432

Gene position: 498768-499655 (Clockwise)

Preceding gene: 28377431

Following gene: 28377433

Centisome position: 15.08

GC content: 45.83

Gene sequence:

>888_bases
ATGGCAGATTATTTAGTAAAAAGCGTCGCGGGTAATGAGATGTTTCGAGCGTACGCAGTTAGCGCAACGGGCGTGGTTGC
TGAAGCCCAACGCCGACATGATACCTGGAGTGCAGCATCAGCAGCGTTAGGCCGCAGCTTGGTTGGTACGTTATTATTAG
CATCATCGGTTTTAAAGGGTGAAGAACAAATGACCGTTAAAATCAACGGGAACGGTCCTGTTGGTGGTATCGTTGTTGAT
GGCAATGCTAAAGGTACGGTCAAGGGGTATTTACAGCACCCCCATGTGCACTTGCCTTTGAATGATAAGCATAAGATCGA
TGTGAAGGCGGCTGTTGGAACTGATGGCTTTTTATCTGTGACTAAGGATCAGGGGGTTGGGGATCCATTCACCGGAACGG
TTGCGTTAGTTTCTGGTGAATTAGGCGAAGACTTTACGTATTACTTAGCACAGTCCGAACAGATTCCATCAGCTGTTGGC
TTGTCGGTGTTTGTAAATGACGACAATTCGATTGGAGTTGCCGGTGGCTTTTTGGTGCAAGTATTGCCAAATGCGACGGA
TGAAGCCATCAGCTCGCTAGAAAACAAGCTCAAAGACATGCCATTAGTCTCCCAATTGATGCGTGATGGTAAGTCACCAG
AAGATATTTTGGATTTATTATTTGATGGTGACGTTAAGGTATTAGATAAAATGCCAGTTAAGTTTGAATGCGATTGTTCT
AAAGAACGATTTGCCGAAGCACTAATGGCTTTGCCCAAGCATGAGGTTCAAGCAATGATTGATGAAGATCATGGTGCCAC
GGCAGTTTGTCATTTTTGTGGGGACCAGTATCAGTTCAGTGAACGCGAACTAGAAGCAGTGCTCTCACGGTCCAAGGGTG
ACGCTTAA

Upstream 100 bases:

>100_bases
TTATGCGTTATGATATTTCAGGAAAATAAATCAATTGCGTTAATTCGGTTATGAGCGTCGGGTCGCAATTAAAGACGGAT
TGAGATAGGAGTATGATTAA

Downstream 100 bases:

>100_bases
TGAATCAAGAGTGGCAGATCGGTGATGTGACGATTCCCAATCGTGTCGTAGTGGCACCGATGGCCGGCGTGACTAACGCG
GCCTTTCGAGTAATCTGCAA

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MADYLVKSVAGNEMFRAYAVSATGVVAEAQRRHDTWSAASAALGRSLVGTLLLASSVLKGEEQMTVKINGNGPVGGIVVD
GNAKGTVKGYLQHPHVHLPLNDKHKIDVKAAVGTDGFLSVTKDQGVGDPFTGTVALVSGELGEDFTYYLAQSEQIPSAVG
LSVFVNDDNSIGVAGGFLVQVLPNATDEAISSLENKLKDMPLVSQLMRDGKSPEDILDLLFDGDVKVLDKMPVKFECDCS
KERFAEALMALPKHEVQAMIDEDHGATAVCHFCGDQYQFSERELEAVLSRSKGDA

Sequences:

>Translated_295_residues
MADYLVKSVAGNEMFRAYAVSATGVVAEAQRRHDTWSAASAALGRSLVGTLLLASSVLKGEEQMTVKINGNGPVGGIVVD
GNAKGTVKGYLQHPHVHLPLNDKHKIDVKAAVGTDGFLSVTKDQGVGDPFTGTVALVSGELGEDFTYYLAQSEQIPSAVG
LSVFVNDDNSIGVAGGFLVQVLPNATDEAISSLENKLKDMPLVSQLMRDGKSPEDILDLLFDGDVKVLDKMPVKFECDCS
KERFAEALMALPKHEVQAMIDEDHGATAVCHFCGDQYQFSERELEAVLSRSKGDA
>Mature_294_residues
ADYLVKSVAGNEMFRAYAVSATGVVAEAQRRHDTWSAASAALGRSLVGTLLLASSVLKGEEQMTVKINGNGPVGGIVVDG
NAKGTVKGYLQHPHVHLPLNDKHKIDVKAAVGTDGFLSVTKDQGVGDPFTGTVALVSGELGEDFTYYLAQSEQIPSAVGL
SVFVNDDNSIGVAGGFLVQVLPNATDEAISSLENKLKDMPLVSQLMRDGKSPEDILDLLFDGDVKVLDKMPVKFECDCSK
ERFAEALMALPKHEVQAMIDEDHGATAVCHFCGDQYQFSERELEAVLSRSKGDA

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=283, Percent_Identity=28.9752650176678, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_LACPL (Q88Z30)

Other databases:

- EMBL:   AL935253
- RefSeq:   NP_784324.1
- ProteinModelPortal:   Q88Z30
- SMR:   Q88Z30
- GeneID:   1061902
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0548
- NMPDR:   fig|220668.1.peg.458
- HOGENOM:   HBG286231
- OMA:   VMLGRAM
- ProtClustDB:   PRK00114
- BioCyc:   LPLA220668:LP_0548-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31472; Mature: 31341

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADYLVKSVAGNEMFRAYAVSATGVVAEAQRRHDTWSAASAALGRSLVGTLLLASSVLKG
CCHHHHHHHCCCHHHHEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EEQMTVKINGNGPVGGIVVDGNAKGTVKGYLQHPHVHLPLNDKHKIDVKAAVGTDGFLSV
CCEEEEEECCCCCEEEEEEECCCCCEEEEEECCCEEEECCCCCCEEEEEEEECCCCCEEE
TKDQGVGDPFTGTVALVSGELGEDFTYYLAQSEQIPSAVGLSVFVNDDNSIGVAGGFLVQ
ECCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHCEEEEEECCCCEEECCHHHEE
VLPNATDEAISSLENKLKDMPLVSQLMRDGKSPEDILDLLFDGDVKVLDKMPVKFECDCS
ECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCEEECCCC
KERFAEALMALPKHEVQAMIDEDHGATAVCHFCGDQYQFSERELEAVLSRSKGDA
HHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADYLVKSVAGNEMFRAYAVSATGVVAEAQRRHDTWSAASAALGRSLVGTLLLASSVLKG
CHHHHHHHCCCHHHHEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EEQMTVKINGNGPVGGIVVDGNAKGTVKGYLQHPHVHLPLNDKHKIDVKAAVGTDGFLSV
CCEEEEEECCCCCEEEEEEECCCCCEEEEEECCCEEEECCCCCCEEEEEEEECCCCCEEE
TKDQGVGDPFTGTVALVSGELGEDFTYYLAQSEQIPSAVGLSVFVNDDNSIGVAGGFLVQ
ECCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHCEEEEEECCCCEEECCHHHEE
VLPNATDEAISSLENKLKDMPLVSQLMRDGKSPEDILDLLFDGDVKVLDKMPVKFECDCS
ECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCEEECCCC
KERFAEALMALPKHEVQAMIDEDHGATAVCHFCGDQYQFSERELEAVLSRSKGDA
HHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566