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The map label for this gene is trx [H]

Identifier: 28199115

GI number: 28199115

Start: 1430070

End: 1431095

Strand: Reverse

Name: trx [H]

Synonym: PD1229

Alternate gene names: 28199115

Gene position: 1431095-1430070 (Counterclockwise)

Preceding gene: 28199124

Following gene: 28199106

Centisome position: 56.79

GC content: 51.17

Gene sequence:

>1026_bases
TTGTTTCAAGATGCATGGTTTTTCCTCTGGTGTCTGCGCTGTATTAGCAGCGCGCCGAAATTGGATTGTCGTGTGTGTCC
GTCATCAGGTGAACCTCTGACCTTGTATCGGTCTGATGTGTCACCATTAATTCATCATCATCAATTGATAGAAGAGTCTT
TGGTTATGTCCGATAAATCCCATGTATTTGATGTGACTGATGCGGATTTTGAGACCGCAGTGTTGAAGAGGTCTTTAGAG
ACTCCTGTATTGGTCGATTTTTGGGCGCCTTGGTGTGCTCCGTGCCGCTCGCTGATTCCGATTTTGGAGAAGTTGGTCGC
CGAATATCGTGGTGGGTTTGAGCTGGCGAAGATCAATGTGGATCAGGAGCAGCAAGTGGCTGCGGCGTTGCAGGTCCGCT
CGGTTCCAATGGTGTATCTGGTCAAGGATGGGCAATTGGTCGATGGTTTTCCAGGTGCCAAGCCTGAAACTCAGGTGCGT
GAGTTTTTGACGAAACATGGGATTCTTCCCGCTCGGTCCGCTGCGTTCAGAGAGGACACGCCCGCCATTCCATTGGATCC
AGAGGCTGAGGTTGAACGGTTGCGTCAGGCACTGGTTGCTGAGCCAGAGAATAATGATCTGAAGCTTGATCTTGCGTTGG
CGTTGCTGAAGACGAATGGCGCTGATGAGGCGGCGGGTCTCATTGATGCGTTGCCTGCGAAACTGGCTACAGATGATCGG
ATGTTACGGGCTAAGGCGTGGCTCCGTTTTATTGAGGTATTGAATGGTGCGCCTAGTCTGGATGTGCTCCAGGGGGCGTG
TGCGGCGGACGCATCGGATTTTGATCAACGTCACTTGCTTGGGGTGCATTTATTGCTTGATGGGCAGTGTGAGGCGGCGT
TGGAGCATTTTTTGGAGATGCTGCGCCAGAATCGCGACTTCAAGGATGGGTTGCCACGTAAAGCGTTGATTGATGCGTTT
TATTTGATCGAAGACAAAGAGTTGGTGGGGCGTTATCGCCGCAAGATGTCAGCATTGTTGTTTTGA

Upstream 100 bases:

>100_bases
ACTGGATGTAGCAGGTGTTGGTACCCTGGCAGTGCGAGTGCGAAGCCGGTGACCGATGCGGTGAAGAGGGCTGCTGCTAT
CGTGCCTGTGCTCCGCCAGA

Downstream 100 bases:

>100_bases
TCGTTATTGATGATGCATCTCTCAGTGCGGCAGGCGGTACTTGGTGTCCGCGCTGTAAGGGTTGCTTTTTCTTTTTTATG
TGAGGGTGAGAATTAATCTG

Product: thioredoxin domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MFQDAWFFLWCLRCISSAPKLDCRVCPSSGEPLTLYRSDVSPLIHHHQLIEESLVMSDKSHVFDVTDADFETAVLKRSLE
TPVLVDFWAPWCAPCRSLIPILEKLVAEYRGGFELAKINVDQEQQVAAALQVRSVPMVYLVKDGQLVDGFPGAKPETQVR
EFLTKHGILPARSAAFREDTPAIPLDPEAEVERLRQALVAEPENNDLKLDLALALLKTNGADEAAGLIDALPAKLATDDR
MLRAKAWLRFIEVLNGAPSLDVLQGACAADASDFDQRHLLGVHLLLDGQCEAALEHFLEMLRQNRDFKDGLPRKALIDAF
YLIEDKELVGRYRRKMSALLF

Sequences:

>Translated_341_residues
MFQDAWFFLWCLRCISSAPKLDCRVCPSSGEPLTLYRSDVSPLIHHHQLIEESLVMSDKSHVFDVTDADFETAVLKRSLE
TPVLVDFWAPWCAPCRSLIPILEKLVAEYRGGFELAKINVDQEQQVAAALQVRSVPMVYLVKDGQLVDGFPGAKPETQVR
EFLTKHGILPARSAAFREDTPAIPLDPEAEVERLRQALVAEPENNDLKLDLALALLKTNGADEAAGLIDALPAKLATDDR
MLRAKAWLRFIEVLNGAPSLDVLQGACAADASDFDQRHLLGVHLLLDGQCEAALEHFLEMLRQNRDFKDGLPRKALIDAF
YLIEDKELVGRYRRKMSALLF
>Mature_341_residues
MFQDAWFFLWCLRCISSAPKLDCRVCPSSGEPLTLYRSDVSPLIHHHQLIEESLVMSDKSHVFDVTDADFETAVLKRSLE
TPVLVDFWAPWCAPCRSLIPILEKLVAEYRGGFELAKINVDQEQQVAAALQVRSVPMVYLVKDGQLVDGFPGAKPETQVR
EFLTKHGILPARSAAFREDTPAIPLDPEAEVERLRQALVAEPENNDLKLDLALALLKTNGADEAAGLIDALPAKLATDDR
MLRAKAWLRFIEVLNGAPSLDVLQGACAADASDFDQRHLLGVHLLLDGQCEAALEHFLEMLRQNRDFKDGLPRKALIDAF
YLIEDKELVGRYRRKMSALLF

Specific function: Unknown

COG id: COG3118

COG function: function code O; Thioredoxin domain-containing protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=105, Percent_Identity=42.8571428571429, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI87081747, Length=295, Percent_Identity=32.2033898305085, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87082331, Length=108, Percent_Identity=40.7407407407407, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788936, Length=104, Percent_Identity=37.5, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI212646193, Length=109, Percent_Identity=38.5321100917431, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573567, Length=114, Percent_Identity=35.0877192982456, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639826, Length=110, Percent_Identity=29.0909090909091, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 38173; Mature: 38173

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQDAWFFLWCLRCISSAPKLDCRVCPSSGEPLTLYRSDVSPLIHHHQLIEESLVMSDKS
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCC
HVFDVTDADFETAVLKRSLETPVLVDFWAPWCAPCRSLIPILEKLVAEYRGGFELAKINV
CEEECCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
DQEQQVAAALQVRSVPMVYLVKDGQLVDGFPGAKPETQVREFLTKHGILPARSAAFREDT
CHHHHHHHHHHHHCCCEEEEEECCEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCC
PAIPLDPEAEVERLRQALVAEPENNDLKLDLALALLKTNGADEAAGLIDALPAKLATDDR
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
MLRAKAWLRFIEVLNGAPSLDVLQGACAADASDFDQRHLLGVHLLLDGQCEAALEHFLEM
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHEEEEEEECCCHHHHHHHHHHH
LRQNRDFKDGLPRKALIDAFYLIEDKELVGRYRRKMSALLF
HHCCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFQDAWFFLWCLRCISSAPKLDCRVCPSSGEPLTLYRSDVSPLIHHHQLIEESLVMSDKS
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCC
HVFDVTDADFETAVLKRSLETPVLVDFWAPWCAPCRSLIPILEKLVAEYRGGFELAKINV
CEEECCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
DQEQQVAAALQVRSVPMVYLVKDGQLVDGFPGAKPETQVREFLTKHGILPARSAAFREDT
CHHHHHHHHHHHHCCCEEEEEECCEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCC
PAIPLDPEAEVERLRQALVAEPENNDLKLDLALALLKTNGADEAAGLIDALPAKLATDDR
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
MLRAKAWLRFIEVLNGAPSLDVLQGACAADASDFDQRHLLGVHLLLDGQCEAALEHFLEM
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHEEEEEEECCCHHHHHHHHHHH
LRQNRDFKDGLPRKALIDAFYLIEDKELVGRYRRKMSALLF
HHCCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]