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The map label for this gene is yheS [H]

Identifier: 28199085

GI number: 28199085

Start: 1392830

End: 1394767

Strand: Reverse

Name: yheS [H]

Synonym: PD1197

Alternate gene names: 28199085

Gene position: 1394767-1392830 (Counterclockwise)

Preceding gene: 28199087

Following gene: 28199078

Centisome position: 55.35

GC content: 53.61

Gene sequence:

>1938_bases
ATGATCTCTCTACGTCATTTCGCAATGCGCCGCGGTGGGCGGTTGTTGCTGTCCAATGTTGATATCACCTTGCATGCGGG
GGATCGTGTTGGCGTGGTTGGTCGCAATGGTGTTGGAAAGTCCAGTCTGTTTGCAGCGATCCGTGGCGAATTAGAAGCGG
ACAAAGGCAATGTTGAGTTACCTGGAAAATTACGTATTGCCAGTGTTGCGCAGGAAACACCCTCCTTATCGGATCTGGCC
CTGGACTTTGTACTCAGTGGTGATGATGTGGTTGCCGAGGTCCTGCGTGTCGAGGCAGAGGCGAATGCACGCGAGGATTG
GGAGGCGGTAGCCGCTGCCCATCAGCGCTTAGCCGAGATCGGCGGTTACGACGCCGAAGCACGTGCAGGTAAATTGCTGC
ATGGCCTGGGTTTTCTCACACAGACGCAGCGGCGTGCTGTCTCGACGTTCTCTGGTGGCTGGCGCGTCCGCTTGAACCTG
GCACGTGCACTGATGATGCCCAGTGATCTGTTGTTACTGGACGAACCAACCAACCATCTGGATATGGATGCCGTGTTCTG
GTTAGAACAATGGTTGCAGAAGTACCCTGGTACGTTGCTGCTGATTAGTCATGACCGTGAGTTTTTGGATAACGTTGCCA
CGCATATCCTGCATTTGCATGATGGTAACGCCAAACTATACGTGGGCGGCTACACCGACTTCGAGCGTCAACGTGCCGAG
CAACTACGCCAGCAACAGATTGCTTTTGAGAAAGAGCAGGCCGAGCGTGTTCACTTGCAGAGCTTCATTGACCGTTTCAA
GGCTAAAGCATCAAAAGCCAAGCAGGCACAAAGCCGGATCAAACGCTTAGAAAAGTTGGCTGGAACGGAGGCTGTCCGTA
TGGAGCGTGAATTCCGTATCACGTTTGCACCGCCAACCAAACAACCGCATTCCTTGATTACGCTGCGCCAGGTGAATTGC
GGTTATTCGGTATTGTCTCCGTCTACACCCTCCGATCCTCCACCTGTTGATATCCATGCGGCAGCACCTTCGCAGCCTGC
CGTGATTCTTCATCGTGTTGATTTTGGACTTGAGGCGGGAGACCGTATTGGGTTGCTTGGTCCCAATGGTGCCGGAAAAT
CGACCCTGGTCAAAACATTGGTGAGTGACCTGGCCCCTTTGACGGGGGAGCGCATCGCTCATCCTGATGTGCGTATTGGC
TATTTTGCACAGCACACGGTTGAATCACTGCACGAGGGACAATCGCCGATTGATCATTTCCGTACCCTTGCGCCGCAAGC
ACCGATCCAATCCATACGCGACTTTTTGGGTAAATGGAATTTTCCTGGAGATCGTGCCTTTGAACCTGTGGATGGTTTTT
CCGGAGGTGAGCGTGCGCGCTTGGCATTGTCGTTGATTGCTTGGCGGCAGCCGAATGTTTTGTTACTTGATGAACCCACC
AACCACCTGGATCTAGAGATGCGCGAAGCCTTGGCTGAGGCGCTGAGTGATTTTGATGGAGCAATTGTGATGGTCTCGCA
CGACCGTCACTTGATTGGCTTAGTGTGCGACACGTTTTGGCGTGTTGCTGATGGTGTGGTCGAGCCGTTTGCTGGTGATC
TTGACCAATACGCTGCTTGGCTGCGGACACGTCCCGCGGCACGTGGTGTGCGCGCCAAGACAGAGGAGGTCAATCAGCCA
CAGGCTTCGTTGACTGCCAAATCGCCTACTTCTCAACTCCCAGTGAAAAAGTCGGTCAACTCACAAAAGCTATTGGTTGC
GGAAAAGCATGTGAGCGAATTGGAGACGCTCTTGACCGAATTGGATCGCAAGCTTGCCGATCCGGTCAATTATGCCAATG
GCGAAGTGATGAGGCGTCTTGGCGATGAGCGCGAGCATGCTGCCAGACGGTTAGCTGAAGCCGAACAGGCTTGGTTTCTG
TTGATGGATGGGGGATGA

Upstream 100 bases:

>100_bases
CTTATGCTGTTTTCCAAACCCAAACAATCATAACGTTAAATAAAATGCCATCTCACAAGCGCTGTTTATCTGAGCTGTTT
CTCTATCAAAGGAAGGTTGC

Downstream 100 bases:

>100_bases
ATCATGATTATGATCAATTGGTTACAAAAATATGCCCGCTCCGCAATATTGGGAGCGCTCCGCAATTTACCGCGTAGGCG
TCACCTTCGCCCCTTTGCGC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MISLRHFAMRRGGRLLLSNVDITLHAGDRVGVVGRNGVGKSSLFAAIRGELEADKGNVELPGKLRIASVAQETPSLSDLA
LDFVLSGDDVVAEVLRVEAEANAREDWEAVAAAHQRLAEIGGYDAEARAGKLLHGLGFLTQTQRRAVSTFSGGWRVRLNL
ARALMMPSDLLLLDEPTNHLDMDAVFWLEQWLQKYPGTLLLISHDREFLDNVATHILHLHDGNAKLYVGGYTDFERQRAE
QLRQQQIAFEKEQAERVHLQSFIDRFKAKASKAKQAQSRIKRLEKLAGTEAVRMEREFRITFAPPTKQPHSLITLRQVNC
GYSVLSPSTPSDPPPVDIHAAAPSQPAVILHRVDFGLEAGDRIGLLGPNGAGKSTLVKTLVSDLAPLTGERIAHPDVRIG
YFAQHTVESLHEGQSPIDHFRTLAPQAPIQSIRDFLGKWNFPGDRAFEPVDGFSGGERARLALSLIAWRQPNVLLLDEPT
NHLDLEMREALAEALSDFDGAIVMVSHDRHLIGLVCDTFWRVADGVVEPFAGDLDQYAAWLRTRPAARGVRAKTEEVNQP
QASLTAKSPTSQLPVKKSVNSQKLLVAEKHVSELETLLTELDRKLADPVNYANGEVMRRLGDEREHAARRLAEAEQAWFL
LMDGG

Sequences:

>Translated_645_residues
MISLRHFAMRRGGRLLLSNVDITLHAGDRVGVVGRNGVGKSSLFAAIRGELEADKGNVELPGKLRIASVAQETPSLSDLA
LDFVLSGDDVVAEVLRVEAEANAREDWEAVAAAHQRLAEIGGYDAEARAGKLLHGLGFLTQTQRRAVSTFSGGWRVRLNL
ARALMMPSDLLLLDEPTNHLDMDAVFWLEQWLQKYPGTLLLISHDREFLDNVATHILHLHDGNAKLYVGGYTDFERQRAE
QLRQQQIAFEKEQAERVHLQSFIDRFKAKASKAKQAQSRIKRLEKLAGTEAVRMEREFRITFAPPTKQPHSLITLRQVNC
GYSVLSPSTPSDPPPVDIHAAAPSQPAVILHRVDFGLEAGDRIGLLGPNGAGKSTLVKTLVSDLAPLTGERIAHPDVRIG
YFAQHTVESLHEGQSPIDHFRTLAPQAPIQSIRDFLGKWNFPGDRAFEPVDGFSGGERARLALSLIAWRQPNVLLLDEPT
NHLDLEMREALAEALSDFDGAIVMVSHDRHLIGLVCDTFWRVADGVVEPFAGDLDQYAAWLRTRPAARGVRAKTEEVNQP
QASLTAKSPTSQLPVKKSVNSQKLLVAEKHVSELETLLTELDRKLADPVNYANGEVMRRLGDEREHAARRLAEAEQAWFL
LMDGG
>Mature_645_residues
MISLRHFAMRRGGRLLLSNVDITLHAGDRVGVVGRNGVGKSSLFAAIRGELEADKGNVELPGKLRIASVAQETPSLSDLA
LDFVLSGDDVVAEVLRVEAEANAREDWEAVAAAHQRLAEIGGYDAEARAGKLLHGLGFLTQTQRRAVSTFSGGWRVRLNL
ARALMMPSDLLLLDEPTNHLDMDAVFWLEQWLQKYPGTLLLISHDREFLDNVATHILHLHDGNAKLYVGGYTDFERQRAE
QLRQQQIAFEKEQAERVHLQSFIDRFKAKASKAKQAQSRIKRLEKLAGTEAVRMEREFRITFAPPTKQPHSLITLRQVNC
GYSVLSPSTPSDPPPVDIHAAAPSQPAVILHRVDFGLEAGDRIGLLGPNGAGKSTLVKTLVSDLAPLTGERIAHPDVRIG
YFAQHTVESLHEGQSPIDHFRTLAPQAPIQSIRDFLGKWNFPGDRAFEPVDGFSGGERARLALSLIAWRQPNVLLLDEPT
NHLDLEMREALAEALSDFDGAIVMVSHDRHLIGLVCDTFWRVADGVVEPFAGDLDQYAAWLRTRPAARGVRAKTEEVNQP
QASLTAKSPTSQLPVKKSVNSQKLLVAEKHVSELETLLTELDRKLADPVNYANGEVMRRLGDEREHAARRLAEAEQAWFL
LMDGG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=556, Percent_Identity=38.8489208633094, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI27881506, Length=539, Percent_Identity=36.178107606679, Blast_Score=338, Evalue=9e-93,
Organism=Homo sapiens, GI10947137, Length=539, Percent_Identity=36.178107606679, Blast_Score=338, Evalue=1e-92,
Organism=Homo sapiens, GI69354671, Length=552, Percent_Identity=32.6086956521739, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI10947135, Length=559, Percent_Identity=32.737030411449, Blast_Score=254, Evalue=2e-67,
Organism=Escherichia coli, GI1789751, Length=643, Percent_Identity=44.3234836702955, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1787041, Length=556, Percent_Identity=33.4532374100719, Blast_Score=289, Evalue=5e-79,
Organism=Escherichia coli, GI1787182, Length=615, Percent_Identity=28.2926829268293, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI2367384, Length=582, Percent_Identity=28.3505154639175, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1788165, Length=171, Percent_Identity=32.7485380116959, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1788506, Length=262, Percent_Identity=26.7175572519084, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787500, Length=231, Percent_Identity=26.8398268398268, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786563, Length=231, Percent_Identity=28.1385281385281, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789891, Length=213, Percent_Identity=26.2910798122066, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI48995001, Length=242, Percent_Identity=26.4462809917355, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788053, Length=179, Percent_Identity=31.2849162011173, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=548, Percent_Identity=38.8686131386861, Blast_Score=353, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17555318, Length=558, Percent_Identity=33.6917562724014, Blast_Score=312, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI17559834, Length=563, Percent_Identity=32.6820603907638, Blast_Score=303, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6321121, Length=569, Percent_Identity=35.3251318101933, Blast_Score=331, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6320874, Length=552, Percent_Identity=31.5217391304348, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6325030, Length=415, Percent_Identity=30.6024096385542, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323278, Length=430, Percent_Identity=28.8372093023256, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324314, Length=233, Percent_Identity=30.0429184549356, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24666836, Length=546, Percent_Identity=37.7289377289377, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24642252, Length=554, Percent_Identity=35.9205776173285, Blast_Score=335, Evalue=6e-92,
Organism=Drosophila melanogaster, GI18859989, Length=554, Percent_Identity=35.9205776173285, Blast_Score=335, Evalue=6e-92,
Organism=Drosophila melanogaster, GI24641342, Length=561, Percent_Identity=32.620320855615, Blast_Score=290, Evalue=3e-78,
Organism=Drosophila melanogaster, GI28574259, Length=201, Percent_Identity=31.3432835820896, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71354; Mature: 71354

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLRHFAMRRGGRLLLSNVDITLHAGDRVGVVGRNGVGKSSLFAAIRGELEADKGNVEL
CCCHHHHHHHCCCEEEEEECEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEC
PGKLRIASVAQETPSLSDLALDFVLSGDDVVAEVLRVEAEANAREDWEAVAAAHQRLAEI
CCCEEEHHHHHCCCCHHHHHHHEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GGYDAEARAGKLLHGLGFLTQTQRRAVSTFSGGWRVRLNLARALMMPSDLLLLDEPTNHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCEEEEECCCCCC
DMDAVFWLEQWLQKYPGTLLLISHDREFLDNVATHILHLHDGNAKLYVGGYTDFERQRAE
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEECCCEEEEECCCCHHHHHHHH
QLRQQQIAFEKEQAERVHLQSFIDRFKAKASKAKQAQSRIKRLEKLAGTEAVRMEREFRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECEEEEE
TFAPPTKQPHSLITLRQVNCGYSVLSPSTPSDPPPVDIHAAAPSQPAVILHRVDFGLEAG
EECCCCCCCCCEEEEEEECCCCEECCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCC
DRIGLLGPNGAGKSTLVKTLVSDLAPLTGERIAHPDVRIGYFAQHTVESLHEGQSPIDHF
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHH
RTLAPQAPIQSIRDFLGKWNFPGDRAFEPVDGFSGGERARLALSLIAWRQPNVLLLDEPT
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
NHLDLEMREALAEALSDFDGAIVMVSHDRHLIGLVCDTFWRVADGVVEPFAGDLDQYAAW
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LRTRPAARGVRAKTEEVNQPQASLTAKSPTSQLPVKKSVNSQKLLVAEKHVSELETLLTE
HHCCCHHCCCCCCHHHCCCCHHHEECCCCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHH
LDRKLADPVNYANGEVMRRLGDEREHAARRLAEAEQAWFLLMDGG
HHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure
MISLRHFAMRRGGRLLLSNVDITLHAGDRVGVVGRNGVGKSSLFAAIRGELEADKGNVEL
CCCHHHHHHHCCCEEEEEECEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEC
PGKLRIASVAQETPSLSDLALDFVLSGDDVVAEVLRVEAEANAREDWEAVAAAHQRLAEI
CCCEEEHHHHHCCCCHHHHHHHEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GGYDAEARAGKLLHGLGFLTQTQRRAVSTFSGGWRVRLNLARALMMPSDLLLLDEPTNHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCEEEEECCCCCC
DMDAVFWLEQWLQKYPGTLLLISHDREFLDNVATHILHLHDGNAKLYVGGYTDFERQRAE
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEECCCEEEEECCCCHHHHHHHH
QLRQQQIAFEKEQAERVHLQSFIDRFKAKASKAKQAQSRIKRLEKLAGTEAVRMEREFRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECEEEEE
TFAPPTKQPHSLITLRQVNCGYSVLSPSTPSDPPPVDIHAAAPSQPAVILHRVDFGLEAG
EECCCCCCCCCEEEEEEECCCCEECCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCC
DRIGLLGPNGAGKSTLVKTLVSDLAPLTGERIAHPDVRIGYFAQHTVESLHEGQSPIDHF
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHH
RTLAPQAPIQSIRDFLGKWNFPGDRAFEPVDGFSGGERARLALSLIAWRQPNVLLLDEPT
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
NHLDLEMREALAEALSDFDGAIVMVSHDRHLIGLVCDTFWRVADGVVEPFAGDLDQYAAW
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LRTRPAARGVRAKTEEVNQPQASLTAKSPTSQLPVKKSVNSQKLLVAEKHVSELETLLTE
HHCCCHHCCCCCCHHHCCCCHHHEECCCCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHH
LDRKLADPVNYANGEVMRRLGDEREHAARRLAEAEQAWFLLMDGG
HHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]