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The map label for this gene is oxyR [H]

Identifier: 262192884

GI number: 262192884

Start: 2088200

End: 2089114

Strand: Reverse

Name: oxyR [H]

Synonym: BMA10247_A2155

Alternate gene names: 262192884

Gene position: 2089114-2088200 (Counterclockwise)

Preceding gene: 126446116

Following gene: 126446551

Centisome position: 88.8

GC content: 66.56

Gene sequence:

>915_bases
ATGGCGTTAACCCTCAGGCAACTGAAGTATTTCGTGGCGACCGCCGAGCTCGGGCAGATCTCGCAGGCGGCGATCCAGTT
GACGATCTCGCAATCGGCCGTCACGAGCGCGATCCGCGAGCTCGAGGACAGCCTCGGCACGCAACTGTTCGTGCGCACGG
CCTCGGGCGTCGCGCTGACCAACACCGGTCGGCGTTTCCTGAATCAGGCGTATACGATCCTGTCGTCGGTCGACGAGGCA
ATGCGCATTCCGAATCTCGAAAGCACGCTGACGGGCACGCTCGCGCTCGCGGCGAGCTACACGGTGCTCGGCTACTTCTT
GCCGCACCACCTGATGCGGCTGCACACGCAGTATCCGCGGCTCACGATCCAGCTTCACGAGCTGAACCGCGAATCGATCG
AGGAGGGCTTGATCGCCGGGCGCTACGACATGGCGGTGCTGCTCACGTCGAACGTGTCGAATCCCGAGCTCGTGCTCGAG
CCGGTGATTCACTCGGCGCGGCGGCTGTGGGTGGGCGCGCACCACCCGCTGCTCAGGCGCGAGAGCGTGACGTTCGCCGA
CGTCGCGCCGGAACCGTTCGTGATGCTGACCGTCGACGAGGCTGCGTATACCGCGCTGCGCTACTGGAACGAGACGCCTT
ACCGGCCGAACGTGATCCTGCGCACGTCGTCGGTCGAGGCGGTGCGCAGCATGGTCGCGAACGGCAGCGGCGTCGCGATC
CTGTCGGACATGGTGTATCGGCCGTGGTCGCTCGAAGGGCGGCGCATCGAGACCGTGCTGCTGCGCGATCCGGTGCCGCC
GATGAGCGTCGGGCTCGCGTGGCGCAGGAACGCCGAGTTCAGTCCGGCGATGCACGCGGTGCGCGAGTATTTCCGGCATA
CGTTCATGGAGCCGCGCATGGGCGGCGGCGCGTGA

Upstream 100 bases:

>100_bases
GACCGGGTGCGAGCGGCGTGCTGCATGCCCGCCCGCGCATTCGAGATCGGGCAATGAGATACTTCGCGCTGCGTTATCGA
TTTTTCAGGCGGGCGGCGGC

Downstream 100 bases:

>100_bases
CGCGCGCAAGCGGGCGGGGGCGCACTCGTGCGTCGGGGCGGCGGGCGTGGGGCGACGCGGTGCCGGCGTCGCGCCATCGC
CCATCGCCCATCGCCCATCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIRELEDSLGTQLFVRTASGVALTNTGRRFLNQAYTILSSVDEA
MRIPNLESTLTGTLALAASYTVLGYFLPHHLMRLHTQYPRLTIQLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLE
PVIHSARRLWVGAHHPLLRRESVTFADVAPEPFVMLTVDEAAYTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
LSDMVYRPWSLEGRRIETVLLRDPVPPMSVGLAWRRNAEFSPAMHAVREYFRHTFMEPRMGGGA

Sequences:

>Translated_304_residues
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIRELEDSLGTQLFVRTASGVALTNTGRRFLNQAYTILSSVDEA
MRIPNLESTLTGTLALAASYTVLGYFLPHHLMRLHTQYPRLTIQLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLE
PVIHSARRLWVGAHHPLLRRESVTFADVAPEPFVMLTVDEAAYTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
LSDMVYRPWSLEGRRIETVLLRDPVPPMSVGLAWRRNAEFSPAMHAVREYFRHTFMEPRMGGGA
>Mature_303_residues
ALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIRELEDSLGTQLFVRTASGVALTNTGRRFLNQAYTILSSVDEAM
RIPNLESTLTGTLALAASYTVLGYFLPHHLMRLHTQYPRLTIQLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEP
VIHSARRLWVGAHHPLLRRESVTFADVAPEPFVMLTVDEAAYTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAIL
SDMVYRPWSLEGRRIETVLLRDPVPPMSVGLAWRRNAEFSPAMHAVREYFRHTFMEPRMGGGA

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=31.6546762589928, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI157672245, Length=229, Percent_Identity=30.5676855895196, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=25.9515570934256, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787879, Length=300, Percent_Identity=32, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=26.6932270916335, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788481, Length=247, Percent_Identity=27.5303643724696, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=26, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788297, Length=315, Percent_Identity=27.6190476190476, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081904, Length=196, Percent_Identity=31.6326530612245, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=296, Percent_Identity=23.9864864864865, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=149, Percent_Identity=28.8590604026846, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786401, Length=280, Percent_Identity=27.1428571428571, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788296, Length=247, Percent_Identity=25.1012145748988, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787806, Length=296, Percent_Identity=23.9864864864865, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082132, Length=145, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI2367136, Length=252, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33965; Mature: 33833

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIRELEDSLGTQLFVRTASGVALT
CCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEEEE
NTGRRFLNQAYTILSSVDEAMRIPNLESTLTGTLALAASYTVLGYFLPHHLMRLHTQYPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTIQLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEPVIHSARRLWVGAHHPLLRR
EEEEEECCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEECCCCCCHHC
ESVTFADVAPEPFVMLTVDEAAYTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
CCCEEEECCCCCEEEEEECHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCEE
LSDMVYRPWSLEGRRIETVLLRDPVPPMSVGLAWRRNAEFSPAMHAVREYFRHTFMEPRM
HHHHHCCCCCCCCCEEEEEEEECCCCCCHHCEEECCCCCCCHHHHHHHHHHHHHHCCCCC
GGGA
CCCC
>Mature Secondary Structure 
ALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIRELEDSLGTQLFVRTASGVALT
CCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEEEE
NTGRRFLNQAYTILSSVDEAMRIPNLESTLTGTLALAASYTVLGYFLPHHLMRLHTQYPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTIQLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEPVIHSARRLWVGAHHPLLRR
EEEEEECCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEECCCCCCHHC
ESVTFADVAPEPFVMLTVDEAAYTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
CCCEEEECCCCCEEEEEECHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCEE
LSDMVYRPWSLEGRRIETVLLRDPVPPMSVGLAWRRNAEFSPAMHAVREYFRHTFMEPRM
HHHHHCCCCCCCCCEEEEEEEECCCCCCHHCEEECCCCCCCHHHHHHHHHHHHHHCCCCC
GGGA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]