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The map label for this gene is mrpC

Identifier: 255767719

GI number: 255767719

Start: 3249427

End: 3249768

Strand: Direct

Name: mrpC

Synonym: BSU31620

Alternate gene names: 255767719

Gene position: 3249427-3249768 (Clockwise)

Preceding gene: 16080213

Following gene: 255767720

Centisome position: 77.08

GC content: 43.57

Gene sequence:

>342_bases
ATGGAAATCTTAATGGCTGTATTAGCCGGTATTATTTTTATGGCTGCTACGTATTTGCTGCTGTCTAAAAGCCTGCTTCG
CGTCATTATCGGAACAGCACTGTTAAGCCATGGCGTTCATTTAATGCTTTTGACTATGGGAGGATTAAAGAAAGGCGCCG
CTCCGATTTTGAGCGAGCATGCCAAATCATTTGTCGATCCGCTTCCGCAAGCCCTGATTTTGACCGCAATTGTCATTTCT
TTTGGCGTTACGTCATTCATCCTCGTCATGGCCTTTCGCGCTTATCAGGAATTGAAATCGGACGATATGGATCAAATGAG
GGGAAATGATCAACATGAATAA

Upstream 100 bases:

>100_bases
AAACGGAGCTCGCCACAGCGACGATATTTGATTTAGGCGTTTATCTTGTTGTCGTAGGCATAACGATGACCATTATTCAA
ACGATTGGAGAGGAAGAATA

Downstream 100 bases:

>100_bases
TTTTGTTATTTTGCCAATCCTGATCCCGCTTTTGTCGGCTATTCTTCTGATTTTCATGACGAAGAATCTTATGCTCATGA
GAATCTTCAGCACGGCGGCA

Product: monovalent cation/H+ antiporter subunit C

Products: NA

Alternate protein names: Mrp complex subunit C; Multiple resistance and pH homeostasis protein C

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MEILMAVLAGIIFMAATYLLLSKSLLRVIIGTALLSHGVHLMLLTMGGLKKGAAPILSEHAKSFVDPLPQALILTAIVIS
FGVTSFILVMAFRAYQELKSDDMDQMRGNDQHE

Sequences:

>Translated_113_residues
MEILMAVLAGIIFMAATYLLLSKSLLRVIIGTALLSHGVHLMLLTMGGLKKGAAPILSEHAKSFVDPLPQALILTAIVIS
FGVTSFILVMAFRAYQELKSDDMDQMRGNDQHE
>Mature_113_residues
MEILMAVLAGIIFMAATYLLLSKSLLRVIIGTALLSHGVHLMLLTMGGLKKGAAPILSEHAKSFVDPLPQALILTAIVIS
FGVTSFILVMAFRAYQELKSDDMDQMRGNDQHE

Specific function: Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual N

COG id: COG1006

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhC subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRPC_BACSU (O05260)

Other databases:

- EMBL:   Z93937
- EMBL:   AL009126
- PIR:   C70010
- RefSeq:   NP_391040.2
- EnsemblBacteria:   EBBACT00000001011
- GeneID:   937139
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31620
- NMPDR:   fig|224308.1.peg.3165
- GenoList:   BSU31620
- GeneTree:   EBGT00050000002119
- HOGENOM:   HBG754275
- ProtClustDB:   PRK08600
- BioCyc:   BSUB:BSU31620-MONOMER
- InterPro:   IPR001133

Pfam domain/function: PF00420 Oxidored_q2

EC number: NA

Molecular weight: Translated: 12285; Mature: 12285

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11815cd4)-; HASH(0x11ae7624)-; HASH(0x11a06ba0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILMAVLAGIIFMAATYLLLSKSLLRVIIGTALLSHGVHLMLLTMGGLKKGAAPILSEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHH
AKSFVDPLPQALILTAIVISFGVTSFILVMAFRAYQELKSDDMDQMRGNDQHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCH
>Mature Secondary Structure
MEILMAVLAGIIFMAATYLLLSKSLLRVIIGTALLSHGVHLMLLTMGGLKKGAAPILSEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHH
AKSFVDPLPQALILTAIVISFGVTSFILVMAFRAYQELKSDDMDQMRGNDQHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10198001; 11356194