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The map label for this gene is mrdB [H]

Identifier: 239618089

GI number: 239618089

Start: 1850026

End: 1851087

Strand: Reverse

Name: mrdB [H]

Synonym: Kole_1721

Alternate gene names: 239618089

Gene position: 1851087-1850026 (Counterclockwise)

Preceding gene: 239618090

Following gene: 239618088

Centisome position: 80.41

GC content: 43.22

Gene sequence:

>1062_bases
ATGAAAAAAGAACATGATGTGATTCTCTTTCTGTCCTACATAATTATTTTAGTTTTCGGGCTGACCATTCTATACAGCGT
AACATGGGGGAGGAGATTCTCCTATCTCTTTTACAGACAACTTTCCTGGGATATACTATCCGTCGGCGTGTTCTTCCTAT
TCAGCAGAATAAAAAGAAAATTCTGGGAAGACAACGCCGTTTATCTTTTGTTGCTTTCTTTTGGGTTACTCGTCGTTGTT
TTATTGACACCACCCGTCGCAGGTGCAAACCGCTGGCTGGATCTTGGAATCGCGAGCTTTCAACCTTCAGAACTCGCAAA
ATTATCTATCGTTATGTTTCTCGCCTGGCTTTATACAAAGGACCAGACTCTGAAAATCGGAATAATCGGATTTTTTACAA
CCATTGCGGCTTCCTTTCTTGTTTTTATCGAACCGGACTTTGGTACAGCCCTCATGCTTTTCGCGTTGTGGTTCGTTATT
ACTTTTGTTAGTGCTAAATTTGACAGGCTCCTGATCGCTTCTTTCATCATCATAATAGCGGTTTCTCCCTTCGTGCTATT
CTTTGGCTTGAAAGAATACCAGTTGAAGCGAATACTGAGTTTTCTCAATCCAGCAGCTTATTCAAGGGAGGCCGCTTACA
ATACAATCCAGGCAATGAGGGCAATAGGTTCCGGCGGATTCTCCGGAAAAGGGTTCTTACAGGGTGATATGAGCAGGTAC
GGGTTCGTTCCTGAAAATCATACAGACTTCATTTTCTCAGCCGTCGGGGAACAATTTGGTTTTTTGGGTTCCGTTTTGCT
TATAGCACTCTATACCGTTCTGATATGGAGAATATGGAAGACAGCAAAAAACACCCATTCTGAATTCATGGCTCTCGTAT
CTACAGGCTTTTTAACCATTATTCTCTTCCACATTATCGAAAACATCGGAATGAATCTCGGGCTTTTCCCGGTCACCGGT
ATCCCCCTGCCCTTCATCAGCTACGGTGGCAGTTCTGCCCTTTTCTTCTCAGCACAGCTCGGCATGATATACGGAGCTTC
TGAAAAAACTGCAAAGACATAG

Upstream 100 bases:

>100_bases
GATTCTGTCAAACTAAACGAATGTTCAAGGTGCGGTTATCCAACAACACAAGAAGTGTGTTCATTCTGTAAACTCACTGA
ACGCCTGGAGCAAAAGCTAA

Downstream 100 bases:

>100_bases
TTTTCCTCCACTTGCGCTATAATTGAAAAGAATAAAGAGGGGAGGTAGCGAAATGAAACTCGTAGAATCTGTTCCTAACT
TCAGCGAAGGAAGAAGAAAA

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKKEHDVILFLSYIIILVFGLTILYSVTWGRRFSYLFYRQLSWDILSVGVFFLFSRIKRKFWEDNAVYLLLLSFGLLVVV
LLTPPVAGANRWLDLGIASFQPSELAKLSIVMFLAWLYTKDQTLKIGIIGFFTTIAASFLVFIEPDFGTALMLFALWFVI
TFVSAKFDRLLIASFIIIIAVSPFVLFFGLKEYQLKRILSFLNPAAYSREAAYNTIQAMRAIGSGGFSGKGFLQGDMSRY
GFVPENHTDFIFSAVGEQFGFLGSVLLIALYTVLIWRIWKTAKNTHSEFMALVSTGFLTIILFHIIENIGMNLGLFPVTG
IPLPFISYGGSSALFFSAQLGMIYGASEKTAKT

Sequences:

>Translated_353_residues
MKKEHDVILFLSYIIILVFGLTILYSVTWGRRFSYLFYRQLSWDILSVGVFFLFSRIKRKFWEDNAVYLLLLSFGLLVVV
LLTPPVAGANRWLDLGIASFQPSELAKLSIVMFLAWLYTKDQTLKIGIIGFFTTIAASFLVFIEPDFGTALMLFALWFVI
TFVSAKFDRLLIASFIIIIAVSPFVLFFGLKEYQLKRILSFLNPAAYSREAAYNTIQAMRAIGSGGFSGKGFLQGDMSRY
GFVPENHTDFIFSAVGEQFGFLGSVLLIALYTVLIWRIWKTAKNTHSEFMALVSTGFLTIILFHIIENIGMNLGLFPVTG
IPLPFISYGGSSALFFSAQLGMIYGASEKTAKT
>Mature_353_residues
MKKEHDVILFLSYIIILVFGLTILYSVTWGRRFSYLFYRQLSWDILSVGVFFLFSRIKRKFWEDNAVYLLLLSFGLLVVV
LLTPPVAGANRWLDLGIASFQPSELAKLSIVMFLAWLYTKDQTLKIGIIGFFTTIAASFLVFIEPDFGTALMLFALWFVI
TFVSAKFDRLLIASFIIIIAVSPFVLFFGLKEYQLKRILSFLNPAAYSREAAYNTIQAMRAIGSGGFSGKGFLQGDMSRY
GFVPENHTDFIFSAVGEQFGFLGSVLLIALYTVLIWRIWKTAKNTHSEFMALVSTGFLTIILFHIIENIGMNLGLFPVTG
IPLPFISYGGSSALFFSAQLGMIYGASEKTAKT

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=312, Percent_Identity=34.2948717948718, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1786277, Length=297, Percent_Identity=31.6498316498317, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39692; Mature: 39692

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEHDVILFLSYIIILVFGLTILYSVTWGRRFSYLFYRQLSWDILSVGVFFLFSRIKRK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWEDNAVYLLLLSFGLLVVVLLTPPVAGANRWLDLGIASFQPSELAKLSIVMFLAWLYTK
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
DQTLKIGIIGFFTTIAASFLVFIEPDFGTALMLFALWFVITFVSAKFDRLLIASFIIIIA
CCEEEEHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSPFVLFFGLKEYQLKRILSFLNPAAYSREAAYNTIQAMRAIGSGGFSGKGFLQGDMSRY
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHC
GFVPENHTDFIFSAVGEQFGFLGSVLLIALYTVLIWRIWKTAKNTHSEFMALVSTGFLTI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILFHIIENIGMNLGLFPVTGIPLPFISYGGSSALFFSAQLGMIYGASEKTAKT
HHHHHHHHCCCCCCCEECCCCCCCHHHCCCCCEEEEEEHHHHEECCCCCCCCC
>Mature Secondary Structure
MKKEHDVILFLSYIIILVFGLTILYSVTWGRRFSYLFYRQLSWDILSVGVFFLFSRIKRK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWEDNAVYLLLLSFGLLVVVLLTPPVAGANRWLDLGIASFQPSELAKLSIVMFLAWLYTK
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
DQTLKIGIIGFFTTIAASFLVFIEPDFGTALMLFALWFVITFVSAKFDRLLIASFIIIIA
CCEEEEHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSPFVLFFGLKEYQLKRILSFLNPAAYSREAAYNTIQAMRAIGSGGFSGKGFLQGDMSRY
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHC
GFVPENHTDFIFSAVGEQFGFLGSVLLIALYTVLIWRIWKTAKNTHSEFMALVSTGFLTI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILFHIIENIGMNLGLFPVTGIPLPFISYGGSSALFFSAQLGMIYGASEKTAKT
HHHHHHHHCCCCCCCEECCCCCCCHHHCCCCCEEEEEEHHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]