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The map label for this gene is apbE [H]

Identifier: 239618063

GI number: 239618063

Start: 1822525

End: 1823565

Strand: Reverse

Name: apbE [H]

Synonym: Kole_1693

Alternate gene names: 239618063

Gene position: 1823565-1822525 (Counterclockwise)

Preceding gene: 239618064

Following gene: 239618062

Centisome position: 79.21

GC content: 45.24

Gene sequence:

>1041_bases
TTGCGGAAAAGAGATTCCCGTGATTCTTTGATAGGAAGAACGATCCTTTATTCAATACTCATGGTCGCTGCTATTGCGAC
CCTTATTTTTGTTTACCTGAAGAACCGACCTGAGGAATACTACACGAGAACTGAATATCTACTGGGCACTTATGTCACCA
TAAAGGTGGCATCGGAGAAGATTTCCCCCGTGATTCTTGCCGATGCAGCTTTCAGAGAAATAACCCGAATCGATAAAAAG
TTTGGATCAGATAGAGGAATAGTGAAGAGTATGGCGGAAGCCGGTGAGAATGGAATGGAAGTGGATGAAGAGACTGCCTT
TTTACTCAGCGCAGTAATCAATATAGCCGAAAAAACCGGTGGAGCTTTTGATCCCACGATTTACCCGATAACCAAACTCT
GGGGATTCGATAGTTCGTCAAGCAAAAAGCGAGTCCCTTCCGAAAAAGAAATCGAGAAAACTCTCGAGCGTGTAGGATAC
AAAAACATCGTTGTCGATGTATCCTCAAGCAAGGTATGGATCCTCAACGGAGCGGAACTCGACCTTTCGGGTATAGCAAA
AGGGTACGCAGTTGATCTTGCTATTGCCAGAATTAAGTCTATGGATGAAACCGCCACCGGGTTCATCGATGCCGGCGGTG
ATATAGGCATAATCGGACCAAAATACGGAAAAAGGCCGTGGGTAATTGGAATCAGGAATCCCAGAAGCGATAGGGCTGAC
GACGTGATTGAGTATGTTTATATGTATGATGGAGCAATTGCCACATCGGGCGATTACGAACGATATTTCATTGAAGACGG
AATCAGATATCATCATATCTTCAATCCTACCACGGGAAGACCCGCTAGATCCGGTGTGATAAGCGCAACGGTAATAAGCA
AAAGCGCTCTGGAAGCTGATGCCTTTGCCACGGCGGCTTTTGTTATAGGAACCTCACCCGGGATAACCTTTTTCCCCAGA
TATGGCGCTCTTGTCATGCTTGTTATGGAAGATCTGAGTACGTACAAATCACCGGGATTTGAGGTGTATCAGAAAAAATG
A

Upstream 100 bases:

>100_bases
TCAACACTACTTATTGTCCTGATTGCGGTACATCTCTGATAAAACGCAGAGGCTTCGACGTTGAAATAGCAAACCTTACC
GAGGAAAGTAGGTGCTCCAA

Downstream 100 bases:

>100_bases
AATACAGGCTATTTAGGCCTTTAGATTTGCTGGTGATAATTTTTCTCGTGGTTACCATATTCGCTTTTTCAGGAAAATCT
CCTGGCCTGGCTCAAAATAT

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRKRDSRDSLIGRTILYSILMVAAIATLIFVYLKNRPEEYYTRTEYLLGTYVTIKVASEKISPVILADAAFREITRIDKK
FGSDRGIVKSMAEAGENGMEVDEETAFLLSAVINIAEKTGGAFDPTIYPITKLWGFDSSSSKKRVPSEKEIEKTLERVGY
KNIVVDVSSSKVWILNGAELDLSGIAKGYAVDLAIARIKSMDETATGFIDAGGDIGIIGPKYGKRPWVIGIRNPRSDRAD
DVIEYVYMYDGAIATSGDYERYFIEDGIRYHHIFNPTTGRPARSGVISATVISKSALEADAFATAAFVIGTSPGITFFPR
YGALVMLVMEDLSTYKSPGFEVYQKK

Sequences:

>Translated_346_residues
MRKRDSRDSLIGRTILYSILMVAAIATLIFVYLKNRPEEYYTRTEYLLGTYVTIKVASEKISPVILADAAFREITRIDKK
FGSDRGIVKSMAEAGENGMEVDEETAFLLSAVINIAEKTGGAFDPTIYPITKLWGFDSSSSKKRVPSEKEIEKTLERVGY
KNIVVDVSSSKVWILNGAELDLSGIAKGYAVDLAIARIKSMDETATGFIDAGGDIGIIGPKYGKRPWVIGIRNPRSDRAD
DVIEYVYMYDGAIATSGDYERYFIEDGIRYHHIFNPTTGRPARSGVISATVISKSALEADAFATAAFVIGTSPGITFFPR
YGALVMLVMEDLSTYKSPGFEVYQKK
>Mature_346_residues
MRKRDSRDSLIGRTILYSILMVAAIATLIFVYLKNRPEEYYTRTEYLLGTYVTIKVASEKISPVILADAAFREITRIDKK
FGSDRGIVKSMAEAGENGMEVDEETAFLLSAVINIAEKTGGAFDPTIYPITKLWGFDSSSSKKRVPSEKEIEKTLERVGY
KNIVVDVSSSKVWILNGAELDLSGIAKGYAVDLAIARIKSMDETATGFIDAGGDIGIIGPKYGKRPWVIGIRNPRSDRAD
DVIEYVYMYDGAIATSGDYERYFIEDGIRYHHIFNPTTGRPARSGVISATVISKSALEADAFATAAFVIGTSPGITFFPR
YGALVMLVMEDLSTYKSPGFEVYQKK

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=249, Percent_Identity=30.5220883534137, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 38201; Mature: 38201

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRDSRDSLIGRTILYSILMVAAIATLIFVYLKNRPEEYYTRTEYLLGTYVTIKVASEK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEEEEECCC
ISPVILADAAFREITRIDKKFGSDRGIVKSMAEAGENGMEVDEETAFLLSAVINIAEKTG
CCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
GAFDPTIYPITKLWGFDSSSSKKRVPSEKEIEKTLERVGYKNIVVDVSSSKVWILNGAEL
CCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEECCEE
DLSGIAKGYAVDLAIARIKSMDETATGFIDAGGDIGIIGPKYGKRPWVIGIRNPRSDRAD
CHHHCCCCHHHHHHHHHHHCCCHHHCCEEECCCCEEEECCCCCCCCEEEEECCCCCCCHH
DVIEYVYMYDGAIATSGDYERYFIEDGIRYHHIFNPTTGRPARSGVISATVISKSALEAD
HHHHHHHHCCCEEECCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHH
AFATAAFVIGTSPGITFFPRYGALVMLVMEDLSTYKSPGFEVYQKK
HHHHEEEEEECCCCCEECCCHHHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MRKRDSRDSLIGRTILYSILMVAAIATLIFVYLKNRPEEYYTRTEYLLGTYVTIKVASEK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEEEEECCC
ISPVILADAAFREITRIDKKFGSDRGIVKSMAEAGENGMEVDEETAFLLSAVINIAEKTG
CCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
GAFDPTIYPITKLWGFDSSSSKKRVPSEKEIEKTLERVGYKNIVVDVSSSKVWILNGAEL
CCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEECCEE
DLSGIAKGYAVDLAIARIKSMDETATGFIDAGGDIGIIGPKYGKRPWVIGIRNPRSDRAD
CHHHCCCCHHHHHHHHHHHCCCHHHCCEEECCCCEEEECCCCCCCCEEEEECCCCCCCHH
DVIEYVYMYDGAIATSGDYERYFIEDGIRYHHIFNPTTGRPARSGVISATVISKSALEAD
HHHHHHHHCCCEEECCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHH
AFATAAFVIGTSPGITFFPRYGALVMLVMEDLSTYKSPGFEVYQKK
HHHHEEEEEECCCCCEECCCHHHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]