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The map label for this gene is alr [H]

Identifier: 239618030

GI number: 239618030

Start: 1788375

End: 1789493

Strand: Reverse

Name: alr [H]

Synonym: Kole_1659

Alternate gene names: 239618030

Gene position: 1789493-1788375 (Counterclockwise)

Preceding gene: 239618031

Following gene: 239618029

Centisome position: 77.73

GC content: 42.45

Gene sequence:

>1119_bases
ATGTTGAGCAGGAGAACCTATCTGGAAATAGATCTGAAAGCTTACAAACAAAACTTAGAGTTTTTCCAGCGAAAAGTTTC
ACCCACAAAAGTTATGGCCGTGGTAAAATCCAACGCCTATGGCCATGGAGCTGTTGGAATTTCAAAAGCTGCTGTTGAAT
CCGGTATTGACATGCTGGCTGTGGCTTTCTTAGAAGAAGGAATCGAACTGCGAAACCATGGAATAAACGTTCCCATACTG
GTATTTAACTATTTTGATCCAGAATACTCCTCTCTAGCACTTGAAAATAACCTTACAATCACAGCCTACTCGATAGAACA
GATGAAAGGAATTAAAAGTGTCCTTGGTAACCAGATCAGAAAACTGAAGGTCCATGTAAATGTGGATACCGGAATGAAGC
GTATCGGTCCCTCTGCTAACGAATGCACATCGCTGATAGAATACCTTCTGGAAAATGGGTTTAGCATAGAAGGAATCTAT
TCACATTTTGCCGTCGCTGATGAAGCAATAGAACAGTTTTCTATAGAGCAGAGAAAAGCCTTTGAATCCGCGGTGAAAAC
CCTTGAAAGCAAAGGGATAAAAATTCCTGTAAAACATCTATGTAACAGCGCGGGTTCATTGCGGTTTAACCGTGAGGAAT
ATAATTATATAAGACTTGGCATAGCCAGTTACGGTTTGCAACCTTCCGGAGATTTCGTCATTCCGGAACTTAAGCCCGTT
TTAACATGGAAAAGCGCTGTATCTTACGTCAAAACTTTAAAGCCAGGTGACAGCGTGAGTTACGGGAGAACCTTTATCGC
GGACAGGAAAATGGTGGTTTCCACCGTACCCGTGGGTTATGGGGATGGTTACAGCAGGGGATTATCCAACCGTGGCGAAG
TGCTAATCGGCGGAAAACGTTGTAAAATCCTTGGTAGAGTCTGTATGGATCAATTCGTGGTAGACGTTACGCACCTGCAC
AAAAAACCAAAAATAGGCGATGAAGTTGTACTGATTGGCTCACAAGGCGAAGAAAGAATAACGGTAGAAGAAATAGCCGA
TTTACTGAACACAATAAACTACGAAATAACCTGTACAATAACCGCCCGCGTGCCAAGGTTATATACTGGAAAGGAGTAA

Upstream 100 bases:

>100_bases
GTCAAAAAGATGAGAGTCTGTACCAAATGTCTTAAAGCCGGAAAAGTCCAGAGAGCAGTATAAAAGCGCGCAAAGCGCGC
TTTTATTTTCAAGGGTGTAT

Downstream 100 bases:

>100_bases
TGAAATGAAACTTAAGGATATCCTTGGAGAAGAAGTGGTAAAGAAAATAAACGAGACACAAAGATCCGATACCCCCATGC
CTTTCGTTTCCGACCTCAAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLSRRTYLEIDLKAYKQNLEFFQRKVSPTKVMAVVKSNAYGHGAVGISKAAVESGIDMLAVAFLEEGIELRNHGINVPIL
VFNYFDPEYSSLALENNLTITAYSIEQMKGIKSVLGNQIRKLKVHVNVDTGMKRIGPSANECTSLIEYLLENGFSIEGIY
SHFAVADEAIEQFSIEQRKAFESAVKTLESKGIKIPVKHLCNSAGSLRFNREEYNYIRLGIASYGLQPSGDFVIPELKPV
LTWKSAVSYVKTLKPGDSVSYGRTFIADRKMVVSTVPVGYGDGYSRGLSNRGEVLIGGKRCKILGRVCMDQFVVDVTHLH
KKPKIGDEVVLIGSQGEERITVEEIADLLNTINYEITCTITARVPRLYTGKE

Sequences:

>Translated_372_residues
MLSRRTYLEIDLKAYKQNLEFFQRKVSPTKVMAVVKSNAYGHGAVGISKAAVESGIDMLAVAFLEEGIELRNHGINVPIL
VFNYFDPEYSSLALENNLTITAYSIEQMKGIKSVLGNQIRKLKVHVNVDTGMKRIGPSANECTSLIEYLLENGFSIEGIY
SHFAVADEAIEQFSIEQRKAFESAVKTLESKGIKIPVKHLCNSAGSLRFNREEYNYIRLGIASYGLQPSGDFVIPELKPV
LTWKSAVSYVKTLKPGDSVSYGRTFIADRKMVVSTVPVGYGDGYSRGLSNRGEVLIGGKRCKILGRVCMDQFVVDVTHLH
KKPKIGDEVVLIGSQGEERITVEEIADLLNTINYEITCTITARVPRLYTGKE
>Mature_372_residues
MLSRRTYLEIDLKAYKQNLEFFQRKVSPTKVMAVVKSNAYGHGAVGISKAAVESGIDMLAVAFLEEGIELRNHGINVPIL
VFNYFDPEYSSLALENNLTITAYSIEQMKGIKSVLGNQIRKLKVHVNVDTGMKRIGPSANECTSLIEYLLENGFSIEGIY
SHFAVADEAIEQFSIEQRKAFESAVKTLESKGIKIPVKHLCNSAGSLRFNREEYNYIRLGIASYGLQPSGDFVIPELKPV
LTWKSAVSYVKTLKPGDSVSYGRTFIADRKMVVSTVPVGYGDGYSRGLSNRGEVLIGGKRCKILGRVCMDQFVVDVTHLH
KKPKIGDEVVLIGSQGEERITVEEIADLLNTINYEITCTITARVPRLYTGKE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=31.4363143631436, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790487, Length=368, Percent_Identity=29.3478260869565, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41303; Mature: 41303

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRRTYLEIDLKAYKQNLEFFQRKVSPTKVMAVVKSNAYGHGAVGISKAAVESGIDMLA
CCCCCEEEEEEHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCHHHHHHHCCHHHHH
VAFLEEGIELRNHGINVPILVFNYFDPEYSSLALENNLTITAYSIEQMKGIKSVLGNQIR
HHHHHHCHHHHHCCCCCEEEEEECCCCCCCCEEEECCEEEEEEEHHHHHHHHHHHCCCEE
KLKVHVNVDTGMKRIGPSANECTSLIEYLLENGFSIEGIYSHFAVADEAIEQFSIEQRKA
EEEEEEEECCCHHHHCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
FESAVKTLESKGIKIPVKHLCNSAGSLRFNREEYNYIRLGIASYGLQPSGDFVIPELKPV
HHHHHHHHHHCCCEEEHHHHCCCCCCEEECCCCCCEEEEEHHHCCCCCCCCEECCCCHHH
LTWKSAVSYVKTLKPGDSVSYGRTFIADRKMVVSTVPVGYGDGYSRGLSNRGEVLIGGKR
HHHHHHHHHHHHCCCCCCCCCCCHHHHCCEEEEEECCCCCCCCHHCCCCCCCCEEECCHH
CKILGRVCMDQFVVDVTHLHKKPKIGDEVVLIGSQGEERITVEEIADLLNTINYEITCTI
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHCCEEEEEEE
TARVPRLYTGKE
EEECCCCCCCCC
>Mature Secondary Structure
MLSRRTYLEIDLKAYKQNLEFFQRKVSPTKVMAVVKSNAYGHGAVGISKAAVESGIDMLA
CCCCCEEEEEEHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCHHHHHHHCCHHHHH
VAFLEEGIELRNHGINVPILVFNYFDPEYSSLALENNLTITAYSIEQMKGIKSVLGNQIR
HHHHHHCHHHHHCCCCCEEEEEECCCCCCCCEEEECCEEEEEEEHHHHHHHHHHHCCCEE
KLKVHVNVDTGMKRIGPSANECTSLIEYLLENGFSIEGIYSHFAVADEAIEQFSIEQRKA
EEEEEEEECCCHHHHCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
FESAVKTLESKGIKIPVKHLCNSAGSLRFNREEYNYIRLGIASYGLQPSGDFVIPELKPV
HHHHHHHHHHCCCEEEHHHHCCCCCCEEECCCCCCEEEEEHHHCCCCCCCCEECCCCHHH
LTWKSAVSYVKTLKPGDSVSYGRTFIADRKMVVSTVPVGYGDGYSRGLSNRGEVLIGGKR
HHHHHHHHHHHHCCCCCCCCCCCHHHHCCEEEEEECCCCCCCCHHCCCCCCCCEEECCHH
CKILGRVCMDQFVVDVTHLHKKPKIGDEVVLIGSQGEERITVEEIADLLNTINYEITCTI
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHCCEEEEEEE
TARVPRLYTGKE
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA