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The map label for this gene is hslV [H]

Identifier: 239618026

GI number: 239618026

Start: 1783611

End: 1784156

Strand: Reverse

Name: hslV [H]

Synonym: Kole_1655

Alternate gene names: 239618026

Gene position: 1784156-1783611 (Counterclockwise)

Preceding gene: 239618027

Following gene: 239618025

Centisome position: 77.5

GC content: 47.07

Gene sequence:

>546_bases
ATGGAACAAATGCATGGAACAACGATACTCGCTGTCAGAAGAAACGGTAAAACGGTAATTGCAGGTGATGGGCAAATCAC
TCTCGGCGCAACGGTAATGAAAGGTTCAGCTAGAAAAGTGAGAAAACTTGGAGACGGCAAAGTACTTGCCGGATTTGCCG
GTTCGGTAGCCGACGCCCTGACGCTCTTCGAAAAATTCGAAGAAAAATACCGCGAAAGCAATTCAAGCCTTTTAAGAGCA
GCAGTGAACCTTGCAAAAGAATGGAGAACGAACAAGATACTCCGGAATCTTGAAGCGCTACTTCTCGTTGCCGATACGGA
CAATATCTTACTTATCTCGGGAAACGGCGAAGTGATTCAACCCGATGAAAACGTCATCGCTATCGGCTCTGGCGGACCAT
ATGCACTTGCCGCTGCCCAGGCCCTACTCAGAAATACAGACATGGATGCCGAAGGAATAGCCAAACAGGCGATGAAAATA
GCGAGTGAGATATGCATTTACACCAACTCGAACTTCACCGTAGAAGCCCTGGAGGTGAAAAAATAA

Upstream 100 bases:

>100_bases
CTGCCGGTGTCCGCCCGGGCCGCAGGGATGGGATTTGAAGAACTCATCGATTTGATAGTTAAAGAAGCCCTGAAACCTGA
TTGAAACTGGAGGTGAAAGA

Downstream 100 bases:

>100_bases
TGCCACAGATAGACGAAGATCTGGCACAGCTTACCCCAAAAAAAATAGTCGAAGAGCTGGACAAATACATCGTAGGCCAG
GCGGAAGCGAAACGTGCCGT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MEQMHGTTILAVRRNGKTVIAGDGQITLGATVMKGSARKVRKLGDGKVLAGFAGSVADALTLFEKFEEKYRESNSSLLRA
AVNLAKEWRTNKILRNLEALLLVADTDNILLISGNGEVIQPDENVIAIGSGGPYALAAAQALLRNTDMDAEGIAKQAMKI
ASEICIYTNSNFTVEALEVKK

Sequences:

>Translated_181_residues
MEQMHGTTILAVRRNGKTVIAGDGQITLGATVMKGSARKVRKLGDGKVLAGFAGSVADALTLFEKFEEKYRESNSSLLRA
AVNLAKEWRTNKILRNLEALLLVADTDNILLISGNGEVIQPDENVIAIGSGGPYALAAAQALLRNTDMDAEGIAKQAMKI
ASEICIYTNSNFTVEALEVKK
>Mature_181_residues
MEQMHGTTILAVRRNGKTVIAGDGQITLGATVMKGSARKVRKLGDGKVLAGFAGSVADALTLFEKFEEKYRESNSSLLRA
AVNLAKEWRTNKILRNLEALLLVADTDNILLISGNGEVIQPDENVIAIGSGGPYALAAAQALLRNTDMDAEGIAKQAMKI
ASEICIYTNSNFTVEALEVKK

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=174, Percent_Identity=60.9195402298851, Blast_Score=214, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19379; Mature: 19379

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQMHGTTILAVRRNGKTVIAGDGQITLGATVMKGSARKVRKLGDGKVLAGFAGSVADAL
CCCCCCCEEEEEECCCCEEEECCCEEEEEEEEECCCHHHHHHCCCCCEEECHHHHHHHHH
TLFEKFEEKYRESNSSLLRAAVNLAKEWRTNKILRNLEALLLVADTDNILLISGNGEVIQ
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCCEEC
PDENVIAIGSGGPYALAAAQALLRNTDMDAEGIAKQAMKIASEICIYTNSNFTVEALEVK
CCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEEEEC
K
C
>Mature Secondary Structure
MEQMHGTTILAVRRNGKTVIAGDGQITLGATVMKGSARKVRKLGDGKVLAGFAGSVADAL
CCCCCCCEEEEEECCCCEEEECCCEEEEEEEEECCCHHHHHHCCCCCEEECHHHHHHHHH
TLFEKFEEKYRESNSSLLRAAVNLAKEWRTNKILRNLEALLLVADTDNILLISGNGEVIQ
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCCEEC
PDENVIAIGSGGPYALAAAQALLRNTDMDAEGIAKQAMKIASEICIYTNSNFTVEALEVK
CCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEEEEC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]