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The map label for this gene is fecC [C]

Identifier: 239617973

GI number: 239617973

Start: 1717144

End: 1718046

Strand: Reverse

Name: fecC [C]

Synonym: Kole_1601

Alternate gene names: 239617973

Gene position: 1718046-1717144 (Counterclockwise)

Preceding gene: 239617974

Following gene: 239617972

Centisome position: 74.63

GC content: 46.07

Gene sequence:

>903_bases
TTGTTTGAAGTACTCAAAATAATTAGCGGAAAACTTCTAGGACCCAAAGCGCATCTCTACATGAATCTCCGATTGCCAAG
AGTAATTGTAGGACTGCTGATAGGTGCCGGATTGGCCGTTGCTGGAGATGGCCTTCAGTTAACTTTAATGAACCCTCTCG
CCGATCCCTATATCATAGGGATATCGGCGGGAGCTTCTTTTGGTGCAGTATTGAGCCTTGTTCTTAAAGAGAGTGCCGGT
ATCTTCATAAGTATGGAGGTTCTTTCCTTTATTTTCGCCCTTGTCTCCGCCTTCCTCGTTTATTATCTCGCAAAGAGGGG
AGGAAGGGTGCCGGTAACCTCTTTGATTTTAAGCGGTGTGATAATCTCTTTTCTTTTCAATGCAGCGGTCACTTTTCTTG
TGGTTTTTGCGTGGAAGAACGTTTTGAGCCTACATTTCTGGTCGCTTGGCTCTCTTTCGGGCGTGACATGGGACGATGCT
CTGAAACTACTGCCCGTTGTAATTGCAGAGGTAATCATCTTCTTCTTTTTAAGGCAGAGGATGCTGATAATCGCGATGGG
GGAAGAACACGCCATAACCCTTGGAATCAATCCGGAAAAAATAAAGGTGACTGTTTTCTTTACCGTAGCACTGGTTTCGG
CGATTTCCGTAGCTACAGCGGGATTGATAGGCTTTGTCGGGCTTATTATTCCTCATATAACTCGTCTCATCTTTGGCGTT
GACAGCAGATTCAGCCTCTTTTCAAACGTTGCCATAGGTGGAATCTTTCTCATCGCCTGTGACAGTTTCGCAAGAACCTT
TTTCCAACCTACAGAACTCCCGATAGGAGCCGTAACAGCTCTCGTGGGAGCTCCAATCTTTATCTATCTGATGCGTCGCA
GAGAGGCGATTTCCCGTGAGTGA

Upstream 100 bases:

>100_bases
GTGAATAAATGTGAAACGATTCGTTTTATTCCTTTTGATTCTTTTTAGCTCTTTATTTCTAATAATATGGCTCTCCAGCC
TTGGTACCGTCAGGTACTCA

Downstream 100 bases:

>100_bases
CTTTTTCGTAAGAGTCGAAGGACTCACTTACCGTTACACGAACGAAGAGGTCCTCAAAAACATAAGTTTTTCCGTTGAAA
AAGGCAAGGTTTTAAGTATC

Product: transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MFEVLKIISGKLLGPKAHLYMNLRLPRVIVGLLIGAGLAVAGDGLQLTLMNPLADPYIIGISAGASFGAVLSLVLKESAG
IFISMEVLSFIFALVSAFLVYYLAKRGGRVPVTSLILSGVIISFLFNAAVTFLVVFAWKNVLSLHFWSLGSLSGVTWDDA
LKLLPVVIAEVIIFFFLRQRMLIIAMGEEHAITLGINPEKIKVTVFFTVALVSAISVATAGLIGFVGLIIPHITRLIFGV
DSRFSLFSNVAIGGIFLIACDSFARTFFQPTELPIGAVTALVGAPIFIYLMRRREAISRE

Sequences:

>Translated_300_residues
MFEVLKIISGKLLGPKAHLYMNLRLPRVIVGLLIGAGLAVAGDGLQLTLMNPLADPYIIGISAGASFGAVLSLVLKESAG
IFISMEVLSFIFALVSAFLVYYLAKRGGRVPVTSLILSGVIISFLFNAAVTFLVVFAWKNVLSLHFWSLGSLSGVTWDDA
LKLLPVVIAEVIIFFFLRQRMLIIAMGEEHAITLGINPEKIKVTVFFTVALVSAISVATAGLIGFVGLIIPHITRLIFGV
DSRFSLFSNVAIGGIFLIACDSFARTFFQPTELPIGAVTALVGAPIFIYLMRRREAISRE
>Mature_300_residues
MFEVLKIISGKLLGPKAHLYMNLRLPRVIVGLLIGAGLAVAGDGLQLTLMNPLADPYIIGISAGASFGAVLSLVLKESAG
IFISMEVLSFIFALVSAFLVYYLAKRGGRVPVTSLILSGVIISFLFNAAVTFLVVFAWKNVLSLHFWSLGSLSGVTWDDA
LKLLPVVIAEVIIFFFLRQRMLIIAMGEEHAITLGINPEKIKVTVFFTVALVSAISVATAGLIGFVGLIIPHITRLIFGV
DSRFSLFSNVAIGGIFLIACDSFARTFFQPTELPIGAVTALVGAPIFIYLMRRREAISRE

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=284, Percent_Identity=33.8028169014084, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788004, Length=288, Percent_Identity=31.9444444444444, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790740, Length=278, Percent_Identity=31.6546762589928, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786804, Length=271, Percent_Identity=33.210332103321, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786805, Length=296, Percent_Identity=31.0810810810811, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786347, Length=277, Percent_Identity=28.8808664259928, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32377; Mature: 32377

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEVLKIISGKLLGPKAHLYMNLRLPRVIVGLLIGAGLAVAGDGLQLTLMNPLADPYIIG
CHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCHHEECCCEEEEEECCCCCCEEEE
ISAGASFGAVLSLVLKESAGIFISMEVLSFIFALVSAFLVYYLAKRGGRVPVTSLILSGV
EECCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IISFLFNAAVTFLVVFAWKNVLSLHFWSLGSLSGVTWDDALKLLPVVIAEVIIFFFLRQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLIIAMGEEHAITLGINPEKIKVTVFFTVALVSAISVATAGLIGFVGLIIPHITRLIFGV
HEEEEECCCCEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSRFSLFSNVAIGGIFLIACDSFARTFFQPTELPIGAVTALVGAPIFIYLMRRREAISRE
CCHHHHHHHHHHHHHHEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFEVLKIISGKLLGPKAHLYMNLRLPRVIVGLLIGAGLAVAGDGLQLTLMNPLADPYIIG
CHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCHHEECCCEEEEEECCCCCCEEEE
ISAGASFGAVLSLVLKESAGIFISMEVLSFIFALVSAFLVYYLAKRGGRVPVTSLILSGV
EECCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IISFLFNAAVTFLVVFAWKNVLSLHFWSLGSLSGVTWDDALKLLPVVIAEVIIFFFLRQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLIIAMGEEHAITLGINPEKIKVTVFFTVALVSAISVATAGLIGFVGLIIPHITRLIFGV
HEEEEECCCCEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSRFSLFSNVAIGGIFLIACDSFARTFFQPTELPIGAVTALVGAPIFIYLMRRREAISRE
CCHHHHHHHHHHHHHHEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]