| Definition | Kosmotoga olearia TBF 19.5.1, complete genome. |
|---|---|
| Accession | NC_012785 |
| Length | 2,302,126 |
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The map label for this gene is appF [H]
Identifier: 239617884
GI number: 239617884
Start: 1621943
End: 1623112
Strand: Reverse
Name: appF [H]
Synonym: Kole_1512
Alternate gene names: 239617884
Gene position: 1623112-1621943 (Counterclockwise)
Preceding gene: 239617885
Following gene: 239617883
Centisome position: 70.5
GC content: 41.79
Gene sequence:
>1170_bases ATGAAATTGTTAGAAGTGAGGAACTTAAAAAAATACTTCCCCATAAAACAGGGTTTTCTCATTGACAGGGTGGTTGGTTA TGTTAAAGCGGTAGATGATGTCTCGTTTGATCTTGACAGAGGAAAAACCATTGGTCTTGTTGGTGAATCCGGTTGCGGTA AGACAACCATAGGAAAAACTATCCTCAGGCTTCACGACCTGACTGACGGGGAAATTATCATCGATGGTGAGGATACCACC TTCTATTTCATGAAACCCAGAAAAGCCATGGAGTATTTGAAAGAAAAATACCTTTCAAGACCAGAATTCTCCAATGGTGG AAAGAATCTGCAACCCCATGAAAAACATATATACGACGTCTATAAAAAAGCCAATGAAAATCCAAAAGAGGTTCTTAAAA TCCTTTCGGCTAATCGCAAAGAAAAACTTCTCGAGATAAGAAGAAAAGCCCAGATCGTTTTCCAGGATCCAATGTCCTCC TTGAACCCAAGAATGACCGTGGGACAAATGCTCTCGGAACCGCTTTTGTTCCATGGAATAGCTCAAAATATCGACGAAGC TATTGAGATAGTTAAAAACCTTCTCACCCAGGTTGGTTTGAAACCTTATCATATCGATAGATATCCGCACCAGTTCAGTG GTGGGCAAAGGCAAAGAATCGCCATTGCGAGGGCTGTCAGTGTCAATCCAGAATTGATAGTTCTTGATGAACCAACATCA GCTCTGGATGTTTCCGTCCAGGCCCAGATTGTTAAACTATTAAAAGAACTTCAGGAAAAACTGAACGCAGGTTATGTATT CATTTCCCATGACCTGGCTCTGGTCAGGTTCATAAGCGACGAAGTTGCTGTCATGTATCTGGGAAAAATCGTGGAAAAGG GTGGTAGTGAAGAGGTATTCGACAATCCTTTGCACCCATATACGAAAGCTTTGCTAGCAGCTGCTCCGATTCCGGATCCA AGGAAAAAAAGGAACAGGAAAGAACTGATAGGTGGACAGGTACCGAGTCCCATTAATAGGCCAAGCGGCTGTTTCTTCCA CCCAAGATGTAAATATAAGATGGAAATCTGTTCAAAAGAATACCCACCACTATTCAAGGTTTCAGATAACCATTATGTTG CGTGTCATCTCTATTCCACATCTTCTAAAGAAGGAGGGGAAAAAGCATGA
Upstream 100 bases:
>100_bases GGAAAGAACTGCCACCTTTGGAGGAAGTGGAAAGCGGTCATTTTGTTAGATGTTTCAATCCTGTTGTTAATAAAGTATCT GTTGTCAAGGAGGAAATTAA
Downstream 100 bases:
>100_bases AGAAACTGTTTGTACTCTTGGCGGTGTTCCTTGTTGCCGCAATGATTGTCGCCGTCGAGCCAGAGTACGCTATTGAGGAC TTTAACGGGAAACCCGGGGG
Product: oligopeptide/dipeptide ABC transporter, ATPase subunit
Products: ADP; phosphate; dipeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 389; Mature: 389
Protein sequence:
>389_residues MKLLEVRNLKKYFPIKQGFLIDRVVGYVKAVDDVSFDLDRGKTIGLVGESGCGKTTIGKTILRLHDLTDGEIIIDGEDTT FYFMKPRKAMEYLKEKYLSRPEFSNGGKNLQPHEKHIYDVYKKANENPKEVLKILSANRKEKLLEIRRKAQIVFQDPMSS LNPRMTVGQMLSEPLLFHGIAQNIDEAIEIVKNLLTQVGLKPYHIDRYPHQFSGGQRQRIAIARAVSVNPELIVLDEPTS ALDVSVQAQIVKLLKELQEKLNAGYVFISHDLALVRFISDEVAVMYLGKIVEKGGSEEVFDNPLHPYTKALLAAAPIPDP RKKRNRKELIGGQVPSPINRPSGCFFHPRCKYKMEICSKEYPPLFKVSDNHYVACHLYSTSSKEGGEKA
Sequences:
>Translated_389_residues MKLLEVRNLKKYFPIKQGFLIDRVVGYVKAVDDVSFDLDRGKTIGLVGESGCGKTTIGKTILRLHDLTDGEIIIDGEDTT FYFMKPRKAMEYLKEKYLSRPEFSNGGKNLQPHEKHIYDVYKKANENPKEVLKILSANRKEKLLEIRRKAQIVFQDPMSS LNPRMTVGQMLSEPLLFHGIAQNIDEAIEIVKNLLTQVGLKPYHIDRYPHQFSGGQRQRIAIARAVSVNPELIVLDEPTS ALDVSVQAQIVKLLKELQEKLNAGYVFISHDLALVRFISDEVAVMYLGKIVEKGGSEEVFDNPLHPYTKALLAAAPIPDP RKKRNRKELIGGQVPSPINRPSGCFFHPRCKYKMEICSKEYPPLFKVSDNHYVACHLYSTSSKEGGEKA >Mature_389_residues MKLLEVRNLKKYFPIKQGFLIDRVVGYVKAVDDVSFDLDRGKTIGLVGESGCGKTTIGKTILRLHDLTDGEIIIDGEDTT FYFMKPRKAMEYLKEKYLSRPEFSNGGKNLQPHEKHIYDVYKKANENPKEVLKILSANRKEKLLEIRRKAQIVFQDPMSS LNPRMTVGQMLSEPLLFHGIAQNIDEAIEIVKNLLTQVGLKPYHIDRYPHQFSGGQRQRIAIARAVSVNPELIVLDEPTS ALDVSVQAQIVKLLKELQEKLNAGYVFISHDLALVRFISDEVAVMYLGKIVEKGGSEEVFDNPLHPYTKALLAAAPIPDP RKKRNRKELIGGQVPSPINRPSGCFFHPRCKYKMEICSKEYPPLFKVSDNHYVACHLYSTSSKEGGEKA
Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin
COG id: COG4608
COG function: function code E; ABC-type oligopeptide transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI42490749, Length=292, Percent_Identity=25.6849315068493, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI171184400, Length=177, Percent_Identity=35.5932203389831, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI9961252, Length=152, Percent_Identity=36.8421052631579, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4505771, Length=152, Percent_Identity=36.8421052631579, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI9961250, Length=152, Percent_Identity=36.8421052631579, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI42741659, Length=152, Percent_Identity=36.1842105263158, Blast_Score=67, Evalue=4e-11, Organism=Escherichia coli, GI1789962, Length=374, Percent_Identity=41.9786096256684, Blast_Score=279, Evalue=2e-76, Organism=Escherichia coli, GI1787500, Length=375, Percent_Identity=39.4666666666667, Blast_Score=251, Evalue=4e-68, Organism=Escherichia coli, GI145693107, Length=337, Percent_Identity=42.1364985163205, Blast_Score=232, Evalue=3e-62, Organism=Escherichia coli, GI1789963, Length=350, Percent_Identity=36, Blast_Score=204, Evalue=9e-54, Organism=Escherichia coli, GI1787758, Length=215, Percent_Identity=50.6976744186047, Blast_Score=204, Evalue=1e-53, Organism=Escherichia coli, GI1788506, Length=311, Percent_Identity=40.8360128617363, Blast_Score=203, Evalue=1e-53, Organism=Escherichia coli, GI48994883, Length=378, Percent_Identity=35.4497354497354, Blast_Score=199, Evalue=3e-52, Organism=Escherichia coli, GI1787759, Length=382, Percent_Identity=32.4607329842932, Blast_Score=167, Evalue=8e-43, Organism=Escherichia coli, GI48994997, Length=312, Percent_Identity=30.7692307692308, Blast_Score=139, Evalue=2e-34, Organism=Escherichia coli, GI1787547, Length=167, Percent_Identity=37.125748502994, Blast_Score=136, Evalue=2e-33, Organism=Escherichia coli, GI1787548, Length=261, Percent_Identity=31.8007662835249, Blast_Score=133, Evalue=2e-32, Organism=Escherichia coli, GI1789891, Length=146, Percent_Identity=43.1506849315069, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI1789032, Length=363, Percent_Identity=27.8236914600551, Blast_Score=119, Evalue=3e-28, Organism=Escherichia coli, GI1787089, Length=284, Percent_Identity=31.3380281690141, Blast_Score=113, Evalue=2e-26, Organism=Escherichia coli, GI1787712, Length=299, Percent_Identity=28.4280936454849, Blast_Score=107, Evalue=2e-24, Organism=Escherichia coli, GI1786398, Length=204, Percent_Identity=33.8235294117647, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1789890, Length=168, Percent_Identity=36.9047619047619, Blast_Score=101, Evalue=7e-23, Organism=Escherichia coli, GI1788225, Length=178, Percent_Identity=34.8314606741573, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788644, Length=177, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=3e-22, Organism=Escherichia coli, GI1787370, Length=169, Percent_Identity=36.6863905325444, Blast_Score=93, Evalue=3e-20, Organism=Escherichia coli, GI1788761, Length=113, Percent_Identity=40.7079646017699, Blast_Score=92, Evalue=8e-20, Organism=Escherichia coli, GI1787029, Length=161, Percent_Identity=34.1614906832298, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1790467, Length=294, Percent_Identity=23.469387755102, Blast_Score=89, Evalue=6e-19, Organism=Escherichia coli, GI1786872, Length=184, Percent_Identity=31.5217391304348, Blast_Score=89, Evalue=7e-19, Organism=Escherichia coli, GI87081709, Length=193, Percent_Identity=27.979274611399, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI87081791, Length=174, Percent_Identity=30.4597701149425, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789672, Length=169, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=2e-17, Organism=Escherichia coli, GI1790162, Length=313, Percent_Identity=26.8370607028754, Blast_Score=83, Evalue=3e-17, Organism=Escherichia coli, GI1788450, Length=172, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=8e-17, Organism=Escherichia coli, GI1786563, Length=144, Percent_Identity=34.7222222222222, Blast_Score=80, Evalue=3e-16, Organism=Escherichia coli, GI87082267, Length=168, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=1e-15, Organism=Escherichia coli, GI87081834, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1786703, Length=242, Percent_Identity=28.5123966942149, Blast_Score=74, Evalue=2e-14, Organism=Escherichia coli, GI1788165, Length=104, Percent_Identity=40.3846153846154, Blast_Score=72, Evalue=6e-14, Organism=Escherichia coli, GI1789864, Length=119, Percent_Identity=31.0924369747899, Blast_Score=68, Evalue=8e-13, Organism=Escherichia coli, GI1790534, Length=146, Percent_Identity=30.8219178082192, Blast_Score=65, Evalue=9e-12, Organism=Escherichia coli, GI1789991, Length=132, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=1e-11, Organism=Escherichia coli, GI1786345, Length=125, Percent_Identity=30.4, Blast_Score=64, Evalue=2e-11, Organism=Escherichia coli, GI1787112, Length=123, Percent_Identity=35.7723577235772, Blast_Score=63, Evalue=3e-11, Organism=Escherichia coli, GI1787792, Length=92, Percent_Identity=32.6086956521739, Blast_Score=63, Evalue=3e-11, Organism=Escherichia coli, GI1787143, Length=91, Percent_Identity=41.7582417582418, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1789586, Length=298, Percent_Identity=24.496644295302, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI193211015, Length=273, Percent_Identity=29.3040293040293, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI212646699, Length=279, Percent_Identity=28.673835125448, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI25146777, Length=149, Percent_Identity=34.8993288590604, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193211017, Length=90, Percent_Identity=43.3333333333333, Blast_Score=70, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193202349, Length=157, Percent_Identity=33.7579617834395, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71996809, Length=90, Percent_Identity=43.3333333333333, Blast_Score=69, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17558664, Length=203, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17565938, Length=99, Percent_Identity=40.4040404040404, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193209708, Length=144, Percent_Identity=34.7222222222222, Blast_Score=66, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324985, Length=178, Percent_Identity=30.3370786516854, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6323217, Length=172, Percent_Identity=30.8139534883721, Blast_Score=63, Evalue=8e-11, Organism=Drosophila melanogaster, GI24641565, Length=97, Percent_Identity=41.2371134020619, Blast_Score=74, Evalue=2e-13, Organism=Drosophila melanogaster, GI85726357, Length=99, Percent_Identity=41.4141414141414, Blast_Score=72, Evalue=7e-13, Organism=Drosophila melanogaster, GI17136662, Length=178, Percent_Identity=33.1460674157303, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI281363262, Length=162, Percent_Identity=34.5679012345679, Blast_Score=67, Evalue=3e-11, Organism=Drosophila melanogaster, GI24653245, Length=162, Percent_Identity=34.5679012345679, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 44024; Mature: 44024
Theoretical pI: Translated: 9.46; Mature: 9.46
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLLEVRNLKKYFPIKQGFLIDRVVGYVKAVDDVSFDLDRGKTIGLVGESGCGKTTIGKT CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCHHHHHH ILRLHDLTDGEIIIDGEDTTFYFMKPRKAMEYLKEKYLSRPEFSNGGKNLQPHEKHIYDV HHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH YKKANENPKEVLKILSANRKEKLLEIRRKAQIVFQDPMSSLNPRMTVGQMLSEPLLFHGI HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHEEEECCHHHCCCCHHHHHHHCCHHHHHHH AQNIDEAIEIVKNLLTQVGLKPYHIDRYPHQFSGGQRQRIAIARAVSVNPELIVLDEPTS HHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHEEEEEEEEECCCCEEEEECCCC ALDVSVQAQIVKLLKELQEKLNAGYVFISHDLALVRFISDEVAVMYLGKIVEKGGSEEVF HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH DNPLHPYTKALLAAAPIPDPRKKRNRKELIGGQVPSPINRPSGCFFHPRCKYKMEICSKE CCCCCHHHHHHHHHCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHCCC YPPLFKVSDNHYVACHLYSTSSKEGGEKA CCCEEEECCCCEEEEEEEECCCCCCCCCC >Mature Secondary Structure MKLLEVRNLKKYFPIKQGFLIDRVVGYVKAVDDVSFDLDRGKTIGLVGESGCGKTTIGKT CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCHHHHHH ILRLHDLTDGEIIIDGEDTTFYFMKPRKAMEYLKEKYLSRPEFSNGGKNLQPHEKHIYDV HHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH YKKANENPKEVLKILSANRKEKLLEIRRKAQIVFQDPMSSLNPRMTVGQMLSEPLLFHGI HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHEEEECCHHHCCCCHHHHHHHCCHHHHHHH AQNIDEAIEIVKNLLTQVGLKPYHIDRYPHQFSGGQRQRIAIARAVSVNPELIVLDEPTS HHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHEEEEEEEEECCCCEEEEECCCC ALDVSVQAQIVKLLKELQEKLNAGYVFISHDLALVRFISDEVAVMYLGKIVEKGGSEEVF HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH DNPLHPYTKALLAAAPIPDPRKKRNRKELIGGQVPSPINRPSGCFFHPRCKYKMEICSKE CCCCCHHHHHHHHHCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHCCC YPPLFKVSDNHYVACHLYSTSSKEGGEKA CCCEEEECCCCEEEEEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; dipeptides [Periplasm]; H2O [C]
Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7997159; 9384377 [H]