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The map label for this gene is tktB [C]

Identifier: 239617284

GI number: 239617284

Start: 944795

End: 946699

Strand: Reverse

Name: tktB [C]

Synonym: Kole_0893

Alternate gene names: 239617284

Gene position: 946699-944795 (Counterclockwise)

Preceding gene: 239617285

Following gene: 239617283

Centisome position: 41.12

GC content: 43.41

Gene sequence:

>1905_bases
ATGGCGAAAAAAAAGCTTTCAGAACAGAAAATAGCTGAACTCAAAGAACTTGGACGTATCTGTCGTGGTGATATCTTAAA
GATGACCACAGTTGCTAAATCAGGTCATCCTGGTGGTTCGATGTCATCGATAGATATCTACCTTATGCTTTATGCGTATG
CAAATATCGATCCTGAAAATCCTTTCGATCCTAACAGAGACAGGGTTGTTATTAGTCATGGCCATACTTCTCCAGGTGTT
TATGCGGCACTTGGGAGACTTGGTTTTTTCAATATTGACGAAGTTATTGCAGGATTCAGACATGCTGGCAGTATTTATGA
GGGTCACATAACCCGTGGCATACCTGGTGTGGAATGGACTACCGGTAATCTCGGGCAAGGGCTTTCTGCCGGTGTTGGTA
TGGCCCTTGCTTCTAAGATAAGCGGCAAGAATTTCCAGGTTTACGTTGCAATGGGTGATGCTGAACAGGCAAAAGGACAG
GTTGCTGAAGCCAGAAGGACAGCGGTGAAGTACGGGTTGAACAATCTGGTGGCAGTTATCGATTATAACGATGCACAGAT
ATCTGGAAGAGCTCATGATGTTATGTTTGTCGATATAAAGGCTAATTATGAAGCTGACGGCTGGAAAGTCATCGAAGTCG
ATGGCCACGATTACGAAGCTCTTAACGATGCGCTGTGCGAAGCTTCCAATTATTCGGAGGGACCTGTGGTAATAATTGCG
AAAACAGTTATGGGTAAAGGTGTCAGCTTTATGGAAGATGTCGTTGGATATCACGGAAAGCCACTAGATCTGGAAGCTTG
TAAGAAGGCTCTCGCTGAACTCGGAGTAGAAAATGATCTTGAAAAGTACCTTGAGATGAGAAAGAAATTACCTTCCTATC
ACGAGCCAATTGTACCGCCGACGGAGTTCGTTGAAATCGATCCCGGAACACCGATAACTTACGGCGCTTCTGAAAAACTT
GATAATCGTTCCGCTTTCGGGAAGGCTTTAGCGGATCTTGCAAAGATTAACAAAGGAAAGGCGCCCATAGCGGTTGTTGA
TTGCGACCTCAAACCTTCAACGAAACTTGAGGATTTCGAAAAAGTATGGCCCGAGAATTTTGTCCAGATCGGTGTGCAGG
AACACAACGCTGTAACGGTTGCTGGCGCCATGTCCATATCAGGTGCGAAAACATTCTTTGCAGATTTTGGGGTCTTTGGA
ATTGATGAAACCTATAACCAACAAAGACTCAACGATATAAACAAAACTGACTTGAAGGTTGGTGTAACCCACGTGGGTAT
AGATGTTGGGGAAGATGGAAAGACCCATCACTGTCTCGACTATATAGGTGCCATAAAGAATCTATACGGTTTCAAGCTAA
TCGTTCCTGCAGATCCCAACCAGACAGACAGAGCTGTAAGATATGCGGCTGTAAACAAAGGAAATTTCATTATAGCCATG
GGACGCTCGAAAATGGATATAATAACGGACGCAAATGGCAAACCTTTCTTTGGTGATGACTATAAATTTGAATATGGAAA
GGTTGATGTCATTCGCGAAGGAAAAGATGCCACGGTTGTCGTTACAGGACAGGTAACAACAGAAGCAGTTAAAGCTGCTG
ATGAGCTTAAGGCTGAAGGAATAGAAATCACCATTTTGAATGTAAGCTGTCCTCTTGACGCAAATTTTGAGGAAGTAAAG
GAATATCTTAAGGGTAAAGTTTGTTCTTTTGAAGATCATAACGTGAACAGTGGCCTTGGAACGCTCCTTGAAAGCTACTT
TGCATTGGCGGGATTCCTGCCGGAGAAATTCGAAAAAATCGGAATCGATAGGTACTTCATTTCTGGAAGTAAAAAAGACC
TTTATAAAATTGCCGGACTTGACGCGGAATCGATAGCTGAAAGAGTCAGGAAATGGGTGAGATGA

Upstream 100 bases:

>100_bases
TTTTCTTTCAGACACAGATCCAGAAGAACTTCTTAGAGAGAAAGATGAAGACATAGAGCTTGAAGAAGATGATAAATAGT
TGAGGATTGGAGGTATCAGA

Downstream 100 bases:

>100_bases
AAGAGTATTATAAGAAAGTTCAAGAGTTTTGCAAGAAAAACGATTTGGATATTGACACAGAGTGGATTTTCAAAGCTCTG
TGTCATTCTTCTTATGCAAA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MAKKKLSEQKIAELKELGRICRGDILKMTTVAKSGHPGGSMSSIDIYLMLYAYANIDPENPFDPNRDRVVISHGHTSPGV
YAALGRLGFFNIDEVIAGFRHAGSIYEGHITRGIPGVEWTTGNLGQGLSAGVGMALASKISGKNFQVYVAMGDAEQAKGQ
VAEARRTAVKYGLNNLVAVIDYNDAQISGRAHDVMFVDIKANYEADGWKVIEVDGHDYEALNDALCEASNYSEGPVVIIA
KTVMGKGVSFMEDVVGYHGKPLDLEACKKALAELGVENDLEKYLEMRKKLPSYHEPIVPPTEFVEIDPGTPITYGASEKL
DNRSAFGKALADLAKINKGKAPIAVVDCDLKPSTKLEDFEKVWPENFVQIGVQEHNAVTVAGAMSISGAKTFFADFGVFG
IDETYNQQRLNDINKTDLKVGVTHVGIDVGEDGKTHHCLDYIGAIKNLYGFKLIVPADPNQTDRAVRYAAVNKGNFIIAM
GRSKMDIITDANGKPFFGDDYKFEYGKVDVIREGKDATVVVTGQVTTEAVKAADELKAEGIEITILNVSCPLDANFEEVK
EYLKGKVCSFEDHNVNSGLGTLLESYFALAGFLPEKFEKIGIDRYFISGSKKDLYKIAGLDAESIAERVRKWVR

Sequences:

>Translated_634_residues
MAKKKLSEQKIAELKELGRICRGDILKMTTVAKSGHPGGSMSSIDIYLMLYAYANIDPENPFDPNRDRVVISHGHTSPGV
YAALGRLGFFNIDEVIAGFRHAGSIYEGHITRGIPGVEWTTGNLGQGLSAGVGMALASKISGKNFQVYVAMGDAEQAKGQ
VAEARRTAVKYGLNNLVAVIDYNDAQISGRAHDVMFVDIKANYEADGWKVIEVDGHDYEALNDALCEASNYSEGPVVIIA
KTVMGKGVSFMEDVVGYHGKPLDLEACKKALAELGVENDLEKYLEMRKKLPSYHEPIVPPTEFVEIDPGTPITYGASEKL
DNRSAFGKALADLAKINKGKAPIAVVDCDLKPSTKLEDFEKVWPENFVQIGVQEHNAVTVAGAMSISGAKTFFADFGVFG
IDETYNQQRLNDINKTDLKVGVTHVGIDVGEDGKTHHCLDYIGAIKNLYGFKLIVPADPNQTDRAVRYAAVNKGNFIIAM
GRSKMDIITDANGKPFFGDDYKFEYGKVDVIREGKDATVVVTGQVTTEAVKAADELKAEGIEITILNVSCPLDANFEEVK
EYLKGKVCSFEDHNVNSGLGTLLESYFALAGFLPEKFEKIGIDRYFISGSKKDLYKIAGLDAESIAERVRKWVR
>Mature_633_residues
AKKKLSEQKIAELKELGRICRGDILKMTTVAKSGHPGGSMSSIDIYLMLYAYANIDPENPFDPNRDRVVISHGHTSPGVY
AALGRLGFFNIDEVIAGFRHAGSIYEGHITRGIPGVEWTTGNLGQGLSAGVGMALASKISGKNFQVYVAMGDAEQAKGQV
AEARRTAVKYGLNNLVAVIDYNDAQISGRAHDVMFVDIKANYEADGWKVIEVDGHDYEALNDALCEASNYSEGPVVIIAK
TVMGKGVSFMEDVVGYHGKPLDLEACKKALAELGVENDLEKYLEMRKKLPSYHEPIVPPTEFVEIDPGTPITYGASEKLD
NRSAFGKALADLAKINKGKAPIAVVDCDLKPSTKLEDFEKVWPENFVQIGVQEHNAVTVAGAMSISGAKTFFADFGVFGI
DETYNQQRLNDINKTDLKVGVTHVGIDVGEDGKTHHCLDYIGAIKNLYGFKLIVPADPNQTDRAVRYAAVNKGNFIIAMG
RSKMDIITDANGKPFFGDDYKFEYGKVDVIREGKDATVVVTGQVTTEAVKAADELKAEGIEITILNVSCPLDANFEEVKE
YLKGKVCSFEDHNVNSGLGTLLESYFALAGFLPEKFEKIGIDRYFISGSKKDLYKIAGLDAESIAERVRKWVR

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=635, Percent_Identity=31.1811023622047, Blast_Score=263, Evalue=5e-70,
Organism=Homo sapiens, GI4507521, Length=635, Percent_Identity=31.1811023622047, Blast_Score=263, Evalue=5e-70,
Organism=Homo sapiens, GI133778974, Length=578, Percent_Identity=30.9688581314879, Blast_Score=233, Evalue=5e-61,
Organism=Homo sapiens, GI225637459, Length=625, Percent_Identity=27.84, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI225637463, Length=594, Percent_Identity=28.1144781144781, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI225637461, Length=594, Percent_Identity=28.1144781144781, Blast_Score=194, Evalue=3e-49,
Organism=Escherichia coli, GI1788808, Length=683, Percent_Identity=26.7935578330893, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI48994911, Length=595, Percent_Identity=26.0504201680672, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17539652, Length=642, Percent_Identity=29.595015576324, Blast_Score=234, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6325331, Length=671, Percent_Identity=25.9314456035768, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6319593, Length=656, Percent_Identity=25, Blast_Score=143, Evalue=7e-35,
Organism=Drosophila melanogaster, GI45551847, Length=647, Percent_Identity=29.984544049459, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI45550715, Length=647, Percent_Identity=29.984544049459, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24645119, Length=599, Percent_Identity=30.0500834724541, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24666278, Length=606, Percent_Identity=27.5577557755776, Blast_Score=205, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 69201; Mature: 69070

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKKLSEQKIAELKELGRICRGDILKMTTVAKSGHPGGSMSSIDIYLMLYAYANIDPEN
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCCCCCEEEEEEEEEHHCCCCCC
PFDPNRDRVVISHGHTSPGVYAALGRLGFFNIDEVIAGFRHAGSIYEGHITRGIPGVEWT
CCCCCCCEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEEC
TGNLGQGLSAGVGMALASKISGKNFQVYVAMGDAEQAKGQVAEARRTAVKYGLNNLVAVI
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEE
DYNDAQISGRAHDVMFVDIKANYEADGWKVIEVDGHDYEALNDALCEASNYSEGPVVIIA
ECCCCEECCCEEEEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEE
KTVMGKGVSFMEDVVGYHGKPLDLEACKKALAELGVENDLEKYLEMRKKLPSYHEPIVPP
ECHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
TEFVEIDPGTPITYGASEKLDNRSAFGKALADLAKINKGKAPIAVVDCDLKPSTKLEDFE
CCEEEECCCCCEECCCHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHH
KVWPENFVQIGVQEHNAVTVAGAMSISGAKTFFADFGVFGIDETYNQQRLNDINKTDLKV
HHCCCHHEEECEECCCEEEEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEE
GVTHVGIDVGEDGKTHHCLDYIGAIKNLYGFKLIVPADPNQTDRAVRYAAVNKGNFIIAM
EEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHEEEEEEECCCCEEEEE
GRSKMDIITDANGKPFFGDDYKFEYGKVDVIREGKDATVVVTGQVTTEAVKAADELKAEG
CCCCEEEEECCCCCCCCCCCCEEECCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHCC
IEITILNVSCPLDANFEEVKEYLKGKVCSFEDHNVNSGLGTLLESYFALAGFLPEKFEKI
EEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHC
GIDRYFISGSKKDLYKIAGLDAESIAERVRKWVR
CCCEEEECCCCCCCHHEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AKKKLSEQKIAELKELGRICRGDILKMTTVAKSGHPGGSMSSIDIYLMLYAYANIDPEN
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCCCCCEEEEEEEEEHHCCCCCC
PFDPNRDRVVISHGHTSPGVYAALGRLGFFNIDEVIAGFRHAGSIYEGHITRGIPGVEWT
CCCCCCCEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEEC
TGNLGQGLSAGVGMALASKISGKNFQVYVAMGDAEQAKGQVAEARRTAVKYGLNNLVAVI
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEE
DYNDAQISGRAHDVMFVDIKANYEADGWKVIEVDGHDYEALNDALCEASNYSEGPVVIIA
ECCCCEECCCEEEEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEE
KTVMGKGVSFMEDVVGYHGKPLDLEACKKALAELGVENDLEKYLEMRKKLPSYHEPIVPP
ECHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
TEFVEIDPGTPITYGASEKLDNRSAFGKALADLAKINKGKAPIAVVDCDLKPSTKLEDFE
CCEEEECCCCCEECCCHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHH
KVWPENFVQIGVQEHNAVTVAGAMSISGAKTFFADFGVFGIDETYNQQRLNDINKTDLKV
HHCCCHHEEECEECCCEEEEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEE
GVTHVGIDVGEDGKTHHCLDYIGAIKNLYGFKLIVPADPNQTDRAVRYAAVNKGNFIIAM
EEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHEEEEEEECCCCEEEEE
GRSKMDIITDANGKPFFGDDYKFEYGKVDVIREGKDATVVVTGQVTTEAVKAADELKAEG
CCCCEEEEECCCCCCCCCCCCEEECCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHCC
IEITILNVSCPLDANFEEVKEYLKGKVCSFEDHNVNSGLGTLLESYFALAGFLPEKFEKI
EEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHC
GIDRYFISGSKKDLYKIAGLDAESIAERVRKWVR
CCCEEEECCCCCCCHHEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]