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The map label for this gene is murQ [H]

Identifier: 239617269

GI number: 239617269

Start: 924417

End: 925328

Strand: Reverse

Name: murQ [H]

Synonym: Kole_0878

Alternate gene names: 239617269

Gene position: 925328-924417 (Counterclockwise)

Preceding gene: 239617272

Following gene: 239617268

Centisome position: 40.19

GC content: 39.91

Gene sequence:

>912_bases
ATGATAGAAAAACTCGAAACCGAACAGTCAAATCCAAAGTCTTACAATATCGATTCTTTAAGTACGATCGAAATGCTCAG
GCTTATAAACCACGAAGACGCTACTGTACCTTTAGCTGTCGCTGAACAACTCGAAAAAATAGCAACAGTAATTGACATGA
CGGTAAGCTCGATTAGATCAGGCGGAAGGGTAATATACTGTGGGGCTGGAACCAGTGGAAGATTAGCCGTTATTGATGCA
GCGGAAGTCGTTCCCACCTTCGGAGTCAATGAAGGTCTATTTTTACCGTTGATGGCGGGAGGAGAAGAAGCATTTTTTAA
AGCCGTAGAATCTGTAGAAGACGATGAAATTGGCGGCGTAAATGATTTGATAAGTATCGGAGTAAAAAAAGAAGACACCG
TGATCGGTTTAACCGCCAGCGGACGCACCCCTTATGTGAAAGGAATTTTGAAAAAGGCAAAAGAAGTAGGGTGTAGAACC
GTGTTAATTGCCAATGTAGAAAATCCTGAAATAGCACAATGGGCTGATGTAGTTATAAAACTGCGAACCGGTCCAGAGGT
TATAACAGGAAGCACGAGATTAAAAGCTGGAACTTCACAAAAAATGGTTTTAAACATGATAAGTACAGTGACTATGATTA
AACTCGGTAAAGTTTATAAAAATTACATGGTCGACGTCCAGATCCTCAACACGAAGTTAGAAGAACGAGCAACCAAAATT
ATTTCTGAAGTCACAGGAATCAGCAAAGATGAGGCAAAGAAGTTTCTGAAACTATCAGGAAATAAAACAAAGCTTGCTAT
TTTAATGGTACTCTCAGGGAAAACAAAAGAGGAATGTAATAACGTACTTGAGCGCACGGAATTTTTGTCTGAGGCCCTCA
AAATGTTGTCAAATGGCAATAACGCTGATTAA

Upstream 100 bases:

>100_bases
ACTGTTTCCCACATTTTCTCCACCTCTCTCCACCTCTTATGTATTATACAGATTGATATATAATAATATAAAAAACTTAC
CCTATACAAGGAGGAAAACT

Downstream 100 bases:

>100_bases
ACAGAATTTGACTTCGATGGAAGTTTTTTTATAAAATGAAGTTGTATATATAACTAGACATCATAACAAGGAGATGAAGG
TTTTGGAATCTGTTGATAGA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MIEKLETEQSNPKSYNIDSLSTIEMLRLINHEDATVPLAVAEQLEKIATVIDMTVSSIRSGGRVIYCGAGTSGRLAVIDA
AEVVPTFGVNEGLFLPLMAGGEEAFFKAVESVEDDEIGGVNDLISIGVKKEDTVIGLTASGRTPYVKGILKKAKEVGCRT
VLIANVENPEIAQWADVVIKLRTGPEVITGSTRLKAGTSQKMVLNMISTVTMIKLGKVYKNYMVDVQILNTKLEERATKI
ISEVTGISKDEAKKFLKLSGNKTKLAILMVLSGKTKEECNNVLERTEFLSEALKMLSNGNNAD

Sequences:

>Translated_303_residues
MIEKLETEQSNPKSYNIDSLSTIEMLRLINHEDATVPLAVAEQLEKIATVIDMTVSSIRSGGRVIYCGAGTSGRLAVIDA
AEVVPTFGVNEGLFLPLMAGGEEAFFKAVESVEDDEIGGVNDLISIGVKKEDTVIGLTASGRTPYVKGILKKAKEVGCRT
VLIANVENPEIAQWADVVIKLRTGPEVITGSTRLKAGTSQKMVLNMISTVTMIKLGKVYKNYMVDVQILNTKLEERATKI
ISEVTGISKDEAKKFLKLSGNKTKLAILMVLSGKTKEECNNVLERTEFLSEALKMLSNGNNAD
>Mature_303_residues
MIEKLETEQSNPKSYNIDSLSTIEMLRLINHEDATVPLAVAEQLEKIATVIDMTVSSIRSGGRVIYCGAGTSGRLAVIDA
AEVVPTFGVNEGLFLPLMAGGEEAFFKAVESVEDDEIGGVNDLISIGVKKEDTVIGLTASGRTPYVKGILKKAKEVGCRT
VLIANVENPEIAQWADVVIKLRTGPEVITGSTRLKAGTSQKMVLNMISTVTMIKLGKVYKNYMVDVQILNTKLEERATKI
ISEVTGISKDEAKKFLKLSGNKTKLAILMVLSGKTKEECNNVLERTEFLSEALKMLSNGNNAD

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=270, Percent_Identity=50.3703703703704, Blast_Score=251, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32813; Mature: 32813

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKLETEQSNPKSYNIDSLSTIEMLRLINHEDATVPLAVAEQLEKIATVIDMTVSSIRS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GGRVIYCGAGTSGRLAVIDAAEVVPTFGVNEGLFLPLMAGGEEAFFKAVESVEDDEIGGV
CCEEEEECCCCCCCEEEEEHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCH
NDLISIGVKKEDTVIGLTASGRTPYVKGILKKAKEVGCRTVLIANVENPEIAQWADVVIK
HHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHEEEE
LRTGPEVITGSTRLKAGTSQKMVLNMISTVTMIKLGKVYKNYMVDVQILNTKLEERATKI
ECCCCCEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHH
ISEVTGISKDEAKKFLKLSGNKTKLAILMVLSGKTKEECNNVLERTEFLSEALKMLSNGN
HHHHHCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NAD
CCC
>Mature Secondary Structure
MIEKLETEQSNPKSYNIDSLSTIEMLRLINHEDATVPLAVAEQLEKIATVIDMTVSSIRS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GGRVIYCGAGTSGRLAVIDAAEVVPTFGVNEGLFLPLMAGGEEAFFKAVESVEDDEIGGV
CCEEEEECCCCCCCEEEEEHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCH
NDLISIGVKKEDTVIGLTASGRTPYVKGILKKAKEVGCRTVLIANVENPEIAQWADVVIK
HHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHEEEE
LRTGPEVITGSTRLKAGTSQKMVLNMISTVTMIKLGKVYKNYMVDVQILNTKLEERATKI
ECCCCCEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHH
ISEVTGISKDEAKKFLKLSGNKTKLAILMVLSGKTKEECNNVLERTEFLSEALKMLSNGN
HHHHHCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NAD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA